TransCode Therapeutics (NASDAQ: RNAZ) announced it has entered into a definitive agreement to acquire Polynoma LLC, a privately held immuno-oncology company developing seviprotimut-L, a late-stage polyvalent shed antigen vaccine for the adjuvant treatment of stage IIB and IIC melanoma. Concurrent with the acquisition, TransCode secured a $25 million investment from CK Life Sciences Int’l (Holdings) Inc. to fund its lead microRNA candidate, TTX-MC138, through a Phase 2 clinical trial. Philippe Calais, PharmD, PhD, was appointed Chief Executive Officer, succeeding Interim CEO Tom Fitzgerald, who returns to his role as CFO. “This acquisition allows us to create a unique and broader oncology pipeline with Phase 3-ready seviprotimut-L and our TTX-MC138 program,” said Dr. Calais. “Together, these assets position TransCode to deliver meaningful therapeutic advances for patients battling melanoma and metastatic disease.”
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About TransCode Therapeutics
TransCode is a clinical-stage oncology company focused on treating metastatic disease. The Company is committed to defeating cancer through the intelligent design and effective delivery of RNA therapeutics based on its proprietary TTX nanoparticle platform. The Company’s lead therapeutic candidate, TTX-MC138, is focused on treating metastatic tumors which overexpress microRNA-10b, a unique, well-documented biomarker of metastasis. In addition, TransCode has a portfolio of other first-in-class RNA therapeutic candidates designed to overcome the challenges of RNA delivery and thus unlock therapeutic access to a variety of novel genetic targets that could be relevant to treating a variety of cancers.
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