Andreessen Horowitz leads round with participation from Bessemer Venture Partners, Sapphire Ventures, and Navitas Capital as EliseAI scales real-world enterprise AI

EliseAI, the AI company automating complex healthcare and housing systems, today announced its Series E raise of $250 million. The round was led by Andreessen Horowitz (a16z), with participation from new investor Bessemer Venture Partners and existing investors Sapphire Ventures and Navitas Capital.

With this new funding, EliseAI will rapidly expand its team to accelerate product innovation and impact, improving patient experiences, streamlining operations, and advancing AI-driven solutions for customers. The company is actively hiring across all departments including engineering, customer experience, sales and marketing, and strategy and operations, growing its office hubs in New York, San Francisco, Boston, and Chicago.

“EliseAI is built on the belief that AI can dramatically improve how critical industries operate,” said Minna Song, Co-Founder and CEO of EliseAI. “For an average American, healthcare and housing represent approximately 40% of household spending. These two systems are notoriously complex, outdated, and painful to navigate. And we’re here to fix it with agentic AI. We’re excited to partner with both new and returning investors to supercharge our growth and accelerate solutions that reduce costs and increase efficiency in the industries that matter most.”

Since raising its $75 million Series D in August 2024, EliseAI has grown from 150 to over 300 full-time employees and introduced new AI-powered products across both verticals. The company surpassed $100 million in Annual Recurring Revenue (ARR) earlier this year.

Doubling down on healthcare, EliseAI is tackling one of the system’s most expensive pain points: front-desk and call center operations. Healthcare administrative costs total in excess of $600 billion annually in the U.S. due to excessive manual tasks and limited investment in technology.

EliseAI’s automation platform handles complex healthcare workflows, from navigating multi-step scheduling and prior authorizations to capturing nuanced patient concerns – accurately, compliantly, and empathetically. By cutting overhead by up to 25%, slashing wait times, and reducing abandoned calls, EliseAI helps practices keep both staff and patients satisfied.

“EliseAI has transformed our OB GYN call center operations by streamlining complex workflows, reducing patient wait times, improving operational efficiency, and elevating the customer experience,” said Dr. Pierre Hage of Women’s Health CT – Obstetrics & Gynecology. “With EliseAI, we’re on the path to achieving 24/7/365 comprehensive practice management for our patients and staff.”

In the housing sector, EliseAI helps operators tackle rising costs, labor shortages, and high workforce turnover, which can exceed 40% annually. Its platform includes new products such as AI-Guided Tours, Lease Audits, the Fee Transparency Suite, and the Maintenance App, enabling property managers to streamline operations and improve resident experiences. The company supports over 600 owners and operators, including 75% of NMHC’s Top 50 Operators.

“Customers consistently describe EliseAI as the most exciting software solution in the industry. The company already powers 10% of the U.S. apartment market today, with a massive opportunity still ahead of them domestically and abroad as they begin to enter international markets,” said Alex Immerman, partner, a16z Growth. "We're thrilled to be leading Elise’s latest financing as they raise the standard for how people experience two of life’s most essential services: housing and healthcare.”

About EliseAI

EliseAI transforms complex healthcare and housing systems. By deeply integrating into workflows and automating operations, it makes them efficient and cuts costs for all. Its platform supports medical practices with patient scheduling, intake and front-desk operations and helps property managers handle leasing, maintenance and resident engagement. EliseAI replaces fragmented tools with one integrated system that reduces manual work and improves accessibility and experience for residents and patients alike. The company is based in New York with teams in San Francisco, Boston and Chicago. To learn more, visit www.eliseai.com/careers.

About Andreessen Horowitz

Andreessen Horowitz (a16z) is a venture capital firm that backs bold entrepreneurs building the future through technology. Founded in 2009, the firm manages multiple funds across stages, sectors, and geographies with over $46 billion in committed capital across funds. a16z invests in seed to growth-stage companies across AI, bio + healthcare, consumer, crypto, enterprise, fintech, games, infrastructure, and companies building toward American dynamism. For more information, visit www.a16z.com.

View source version on businesswire.com: https://www.businesswire.com/news/home/20250820023566/en/

“EliseAI is built on the belief that AI can dramatically improve how critical industries operate,” said Minna Song, Co-Founder and CEO of EliseAI. “For an average American, healthcare and housing represent approximately 40% of household spending. These two