As filed with the Securities and Exchange Commission on October 29, 2001

                                                      Registration No. 333-

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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                ----------------

                                    FORM S-1
                             REGISTRATION STATEMENT
                                     UNDER
                           THE SECURITIES ACT OF 1933

                                ----------------

                                  ANTHEM, INC.
             (Exact name of Registrant as specified in its charter)

         Indiana                     6324                    35-2145715
     (State or other     (Primary Standard Industrial     (I.R.S. Employer
     jurisdiction of      Classification Code Number)  Identification Number)
    incorporation or
      organization)



                              120 Monument Circle
                          Indianapolis, Indiana 46204
                                 (317) 488-6000
  (Address, including zip code, and telephone number, including area code, of
                   Registrant's principal executive offices)

                                ----------------

                                 David R. Frick
                          Executive Vice President and
                     Chief Legal and Administrative Officer
                                  Anthem, Inc.
                              120 Monument Circle
                          Indianapolis, Indiana 46204
                                 (317) 488-6000
 (Name, address, including zip code, and telephone number, including area code,
                             of agent for service)

                                ----------------

                                   Copies to:
          Tibor D. Klopfer                      William D. Torchiana
          Baker & Daniels                       Sullivan & Cromwell
             Suite 2700                           125 Broad Street
     300 North Meridian Street                New York, New York 10004
    Indianapolis, Indiana 46204                    (212) 558-4000
           (317) 237-0300

                                ----------------

   Approximate date of commencement of proposed sale to the public: As soon as
is practicable after the effective date of this registration statement.
   If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, check the following box. [_]
   If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, check the following box and
list the Securities Act registration statement number of the earlier effective
registration statement for the same offering. [X] 333-67714
   If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [_]
   If this Form is a post-effective amendment filed pursuant to Rule 462(d)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering. [_]
   If delivery of the prospectus is expected to be made pursuant to Rule 434,
check the following box. [_]

                                ----------------

                        CALCULATION OF REGISTRATION FEE

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  Title of Each Class of Securities to be   Proposed Maximum Aggregate         Amount of
                Registered                   Offering Price(1)(2)(3)        Registration Fee
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Common Stock, $.01 par value..............         $285,200,000                 $71,300
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(1) Estimated solely for purposes of calculating the registration fee pursuant
    to Rule 457(o) under the Securities Act of 1933.
(2) A portion of the shares to be registered represents shares that are to be
    offered outside of the United States but that may be resold from time to
    time in the United States. Such shares are not being registered for the
    purpose of sales outside the United States.
(3) Represents the maximum aggregate offering price of additional shares being
    registered.

                                ----------------

   The Registrant hereby amends this Registration Statement on such date or
dates as may be necessary to delay its effective date until the Registrant
shall file a further amendment which specifically states that this Registration
Statement shall thereafter become effective in accordance with Section 8(a) of
the Securities Act of 1933 or until the Registration Statement shall become
effective on such date as the Commission, acting pursuant to said Section 8(a),
may determine.

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                         EXPLANATION AND INCORPORATION
                      OF CERTAIN INFORMATION BY REFERENCE

   This Registration Statement on Form S-1 is being filed with the Securities
and Exchange Commission (the "Commission") by Anthem, Inc., an Indiana
corporation (the "Company"), pursuant to Rule 462(b) under the Securities Act
of 1933, as amended. This Registration Statement incorporates by reference the
contents of the Company's Registration Statement on Form S-1 (Registration No.
333-67714) which was declared effective by the Commission on October 29, 2001
relating to the offering of shares of Common Stock of the Company with a
maximum aggregate offering price of up to $1,702,000,000.


                                   SIGNATURES

   Pursuant to the requirements of the Securities Act of 1933, the Registrant
has duly caused this Registration Statement to be signed on its behalf by the
undersigned, thereunto duly authorized, in the City of Indianapolis, State of
Indiana, on the 29th day of October, 2001.

                                          Anthem, Inc.

                                                 /s/ Larry C. Glasscock
                                          By: _________________________________
                                                     Larry C. Glasscock
                                               President and Chief Executive
                                                          Officer

   Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed by the following persons in the
capacities and on the dates indicated.



              Signature                         Capacity                 Date
              ---------                         --------                 ----

                                                            
      /s/ Larry C. Glasscock           President, Chief Executive  October 29, 2001
______________________________________  Officer and Director
          Larry C. Glasscock            (Principal Executive
                                        Officer)

       /s/ Michael L. Smith            Executive Vice President    October 29, 2001
______________________________________  and Chief Financial and
           Michael L. Smith             Accounting Officer
                                        (Principal Financial
                                        Officer and Principal
                                        Accounting Officer)

                  *                    Director                    October 29, 2001
______________________________________
             L. Ben Lytle

                  *                    Director                    October 29, 2001
______________________________________
            Susan B. Bayh

                  *                    Director                    October 29, 2001
______________________________________
           William B. Hart


                                      S-1




              Signature                         Capacity                 Date
              ---------                         --------                 ----

                                                            
                  *                    Director                    October 29, 2001
______________________________________
           Allan B. Hubbard

                  *                    Director                    October 29, 2001
______________________________________
            Victor S. Liss

                  *                    Director                    October 29, 2001
______________________________________
           William G. Mays

                  *                    Director                    October 29, 2001
______________________________________
        James W. McDowell, Jr.

                  *                    Director                    October 29, 2001
______________________________________
          B. LaRae Orullian

                  *                    Director                    October 29, 2001
______________________________________
    Senator Donald W. Riegle, Jr.

                  *                    Director                    October 29, 2001
______________________________________
           William J. Ryan

                  *                    Director                    October 29, 2001
______________________________________
       George A. Schaefer, Jr.

                  *                    Director                    October 29, 2001
______________________________________
       Dennis J. Sullivan, Jr.

       * By: /s/ David R. Frick

           Attorney-in-Fact




                                      S-2


                               INDEX TO EXHIBITS



 Exhibit
 Number                                Document
 -------                               --------
      
  5      Opinion of Baker & Daniels
 23.1    Consent of Ernst & Young LLP
 23.2    Consent of Baker & Daniels (contained in Exhibit 5)
 23.3    Consent of Robert H. Dobson, FSA, MAAA, Dale S. Hagstrom, FSA, MAAA,
         Daniel J. McCarthy, FSA, MAAA, and Milliman USA, Inc.


                                      E-1