SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                       PURSUANT TO SECTION 13 OR 15(D) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

        Date of Report (Date of earliest event reported): April 28, 2009

                        MERIDIAN INTERSTATE BANCORP, INC.
               --------------------------------------------------
               (Exact Name of Registrant as Specified in Charter)

         Massachusetts                  001-33898                20-4652200
-----------------------------     ---------------------     --------------------
(State or Other Jurisdiction)     (Commission File No.)     (I.R.S. Employer
 of Incorporation)                                           Identification No.)


10 Meridian Street, East Boston, Massachusetts                     02128
----------------------------------------------                  ----------
(Address of Principal Executive Offices)                        (Zip Code)

Registrant's telephone number, including area code:  (617) 567-1500


                                 Not Applicable
          -------------------------------------------------------------
          (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[  ]  Written communications pursuant to Rule 425 under the Securities Act
      (17 CFR 230.425)

[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
      (17 CFR 240.14a-12)

[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))



Item 5.02      Departure  of  Directors  or  Principal  Officers;   Election  of
               Directors;   Appointment   of  Certain   Officers;   Compensatory
               Arrangements of Certain Officers
               -----------------------------------------------------------------

On April 28, 2009,  Meridian  Interstate  Bancorp,  Inc. (the "Company") and its
subsidiary,  East  Boston  Savings  Bank (the  "Bank"),  agreed to hire  Gregory
Derderian,  CPA as the new Chief Financial  Officer of the Company and Bank. Mr.
Derderian is expected to commence his duties on May 18, 2009.

Mr.  Derderian,  age 43,  served as Chief  Financial  Officer and  Treasurer  of
Mechanics Co-operative Bank in Taunton,  Massachusetts beginning in 2003. He has
also  held the  title of  Executive  Vice  President  since  January  2008.  Mr.
Derderian held various finance  positions at First Fed America Bancorp from 1997
to 2003.  He was an internal  auditor  from 1991 to 1995 with  Washington  Trust
after working for four years with Ward, Fisher & Co CPAs.

A press release announcing Mr. Derderian's hiring is filed as Exhibit 99 to this
Current Report.


Item 9.01.     Financial Statements and Exhibits.
               ----------------------------------

          (a)  Not Applicable.

          (b)  Not Applicable.

          (c)  Not Applicable.

          (d)  Exhibits.

          Exhibit No.         Exhibit

          99                  Press Release dated May 4, 2009



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned, hereunto duly authorized.

                                           MERIDIAN INTERSTATE BANCORP, INC.



DATE: May 4, 2009                     By:  \s\ Deborah J. Jackson
                                           ------------------------------------
                                           Deborah J. Jackson
                                           President and Chief Operating Officer