SCHEDULE 14A
                                 (RULE 14a-101)

                     INFORMATION REQUIRED IN PROXY STATEMENT
                            SCHEDULE 14A INFORMATION
           Proxy Statement Pursuant to Section 14(a) of the Securities
                              Exchange Act of 1934

Filed by the Registrant [X]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[ ]     Preliminary Proxy Statement    [ ]    Confidential, For Use of the
                                              Commission Only
                                              (as permitted by Rule 14a-6(e)(2))
[X]     Definitive Proxy Statement
[ ]     Definitive Additional Materials
[ ]     Soliciting Material Pursuant to Rule 14a-12

                                ENZO BIOCHEM, INC.
                 ----------------------------------------------
                (Name of Registrant as Specified in Its Charter)

                                       N/A
--------------------------------------------------------------------------------
     (Name of Person(s) Filing Proxy Statement if Other Than the Registrant)


Payment of Filing Fee (Check the appropriate box):
[X]     No fee required.
[ ]     Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

        (1)   Title of each class of securities to which transaction applies:

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        (2)   Aggregate number of securities to which transaction applies:

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        (3)   Per unit price or other  underlying  value of transaction computed
pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee
is calculated and state how it was determined):

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        (4)   Proposed maximum aggregate value of transaction:

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        (5)   Total fee paid:

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        [ ]   Fee paid previously with preliminary materials:

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        [ ]   Check box if any part of the fee is offset as provided by Exchange
Act Rule  0-11(a)(2)  and identify the filing for which the  offsetting  fee was
paid previously.  Identify the previous filing by registration statement number,
or the Form or Schedule and the date of its filing.

        (1)   Amount previously paid:

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        (2)   Form, Schedule or Registration Statement No.:

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        (3)   Filing Party:

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        (4)   Date Filed:

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                               ENZO BIOCHEM, INC.
                             60 EXECUTIVE BOULEVARD
                           FARMINGDALE, NEW YORK 11735
                                 (631) 755-5500

                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                         TO BE HELD ON JANUARY 19, 2006

To the Shareholders of Enzo Biochem, Inc.:

         NOTICE IS HEREBY GIVEN that the Annual Meeting of  Shareholders of Enzo
Biochem,  Inc.,  a New York  corporation  (the  "Company"),  will be held at The
Hilton Long  Island/Huntington,  598 Broadhollow  Road,  Melville,  New York, on
January 19,  2006,  at 9:30 a.m.,  local time (the  "Annual  Meeting"),  for the
following purposes:

1.       To elect Elazar Rabbani, Ph.D., John B. Sias and Marcus A. Conant, M.D.
         as Class III  Directors  for a term of three  (3) years or until  their
         respective successors are elected and qualified;

2.       To ratify and approve the  amendment and  restatement  of the Company's
         2005  Equity  Compensation  Incentive  Plan among  other  things to (a)
         permit  restricted stock unit awards to be made under the plan, (b) add
         specific performance criteria that may be used to establish performance
         objectives  for  awards  intended  to  qualify  as   "performance-based
         compensation"  under  Section  162(m) of the  Internal  Revenue Code of
         1986,  as amended (the  "Code"),  and (c)  eliminate  automatic  annual
         option grants to the Company's non-employee directors;

3.       To  ratify  the  appointment  of  Ernst  & Young  LLP as the  Company's
         independent  registered public accounting firm for the Company's fiscal
         year ending July 31, 2006; and

4.       To transact such other  business as may properly come before the Annual
         Meeting or any adjournment thereof.

         The close of business on November 23, 2005 has been fixed as the record
date for the determination of shareholders  entitled to notice of and to vote at
the Annual Meeting. The transfer books of the Company will not be closed.

         All  shareholders  are cordially  invited to attend the Annual Meeting.
Please note that you will be asked to present valid picture identification, such
as a driver's  license or passport,  in order to attend the Annual Meeting.  The
use  of  cameras,  recording  devices  and  other  electronic  devices  will  be
prohibited at the Annual Meeting.

         Whether or not you expect to attend,  you are  requested to sign,  date
and return the enclosed proxy promptly.  Shareholders who execute proxies retain
the right to  revoke  them at any time  prior to the  voting  thereof  by filing
written  notice  of such  revocation  with  the  Secretary  of the  Company,  by
submission of a duly executed  proxy bearing a later date or by voting in person
at the Annual Meeting of Shareholders. Attendance at the Annual Meeting will not
in and of itself constitute revocation of a proxy. Any written notice revoking a
proxy should be sent to Enzo Biochem, Inc., 60 Executive Boulevard, Farmingdale,
New York 11735,  Attention:  Shahram K. Rabbani,  Secretary.  A return  envelope
which  requires no postage if mailed in the United  States is enclosed  for your
convenience.

                                   By Order of the Board of Directors,


                                   Shahram K. Rabbani, SECRETARY

Farmingdale, New York
November 28, 2005



                               ENZO BIOCHEM, INC.
                             60 EXECUTIVE BOULEVARD
                           FARMINGDALE, NEW YORK 11735
                                 (631) 755-5500

                                   -----------


                                 PROXY STATEMENT


                                   -----------

                         ANNUAL MEETING OF SHAREHOLDERS
                         TO BE HELD ON JANUARY 19, 2006

         This Proxy Statement is furnished in connection  with the  solicitation
by the Board of Directors of Enzo  Biochem,  Inc., a New York  corporation  (the
"Company"),  of  proxies  in  the  enclosed  form  for  the  Annual  Meeting  of
Shareholders  to be held at The Hilton  Long  Island/Huntington,  598  Broadview
Road,  Melville,  New York, on January 19, 2006,  at 9:30 a.m.,  local time (the
"Annual  Meeting"),  and for any  adjournment or adjournments  thereof,  for the
purposes set forth in the preceding  Notice of Annual  Meeting of  Shareholders.
The persons  named in the enclosed  form of proxy will vote the shares for which
they are  appointed  in  accordance  with  the  directions  of the  shareholders
appointing  them. In the absence of such  directions,  such shares will be voted
FOR  Proposals 1, 2 and 3 listed in the  preceding  Notice of Annual  Meeting of
Shareholders and, in their best judgment,  will be voted on any other matters as
may come before the Annual Meeting. Any shareholder giving a proxy has the power
to  revoke  the same at any time  before it is voted by  timely  filing  written
notice  of  such  revocation  with  the  Secretary  of the  Company,  by  timely
submission of a duly executed  proxy bearing a later date or by voting in person
at the  Annual  Meeting.  Attendance  at the Annual  Meeting  will not in and of
itself  constitute  revocation of a proxy.  Any written notice  revoking a proxy
should be sent to Enzo Biochem, Inc., 60 Executive Boulevard,  Farmingdale,  New
York 11735,  Attn.:  Shahram K.  Rabbani,  Secretary.  A return  envelope  which
requires  no  postage  if  mailed in the  United  States  is  enclosed  for your
convenience.

         The expense of the  solicitation of proxies for the meeting,  including
the cost of mailing, will be borne by the Company. In addition to mailing copies
of the  enclosed  proxy  materials  to  shareholders,  the  Company  may request
persons,  and reimburse them for their expenses with respect  thereto,  who hold
stock in their  names or  custody or in the names of  nominees  for  others,  to
forward  copies of such  materials to those  persons for whom they hold stock of
the  Company and to request  authority  for the  execution  of the  proxies.  In
addition to the solicitation of proxies by mail, it is expected that some of the
officers,  directors and regular  employees of the Company,  without  additional
compensation,  may  solicit  proxies  on  behalf of the  Board of  Directors  by
telephone, telefax, and personal interview.

         The  principal  executive  offices  of the  Company  are  located at 60
Executive Boulevard,  Farmingdale, New York 11735. The approximate date on which
this Proxy  Statement and the  accompanying  form of proxy will first be sent or
given to the Company's shareholders is November 28, 2005.

VOTING SECURITIES

         Only  holders of record of shares of common  stock,  par value $.01 per
share  (the  "Common  Stock"),  of the  Company as of the close of  business  on
November  23,  2005 are  entitled  to vote at the Annual  Meeting  (the  "Record
Date").  On the Record Date there were issued and outstanding  32,293,757 shares
of Common Stock.  Each outstanding  share of Common Stock is entitled to one (1)
vote upon all matters to be acted upon at the Annual  Meeting.  The holders of a
majority of the outstanding shares of Common Stock as of the Record Date must be
present in person or by proxy at the Annual  Meeting to  constitute a quorum for
the transaction of business at the Annual Meeting.



         The  election of a nominee for  director  requires a plurality of votes
(i.e.,  an excess of votes  over those cast for an  opposing  candidate)  in the
event that more than one  candidate is running for a vacancy.  Shareholders  may
either vote "for" or "withhold" their vote for the director nominees. A properly
executed  proxy  marked  "withhold"  with respect to the election of one or more
directors will not be voted with respect to the director or directors,  although
it will be counted for purposes of  determining  whether there is a quorum.  The
ratification  and approval of Proposal 2 and the ratification of Proposal 3 will
require  the  affirmative  vote of the  majority of the votes cast by holders of
shares of Common Stock present in person or  represented  by proxy at the Annual
Meeting and entitled to vote on such proposals. Abstentions and broker non-votes
are not  counted as votes cast on any matter to which they  relate and will have
no effect  on the  outcome  of the vote with  respect  to any  matter.  A broker
non-vote  occurs  when a broker  or other  nominee  does not have  discretionary
authority  and  has not  received  instructions  with  respect  to a  particular
proposal.  Proxy ballots are received and  tabulated by the  Company's  transfer
agent and certified by the inspector of election.

HOUSEHOLDING OF ANNUAL MEETING MATERIALS

         Some brokers and other nominee record holders may be  participating  in
the practice of "householding"  proxy statements.  This means that only one copy
of the  proxy  statement  may  have  been  sent to  multiple  shareholders  in a
shareholder's  household.  The Company will promptly  deliver a separate copy of
the proxy  statement to any  shareholder  who contacts  the  Company's  investor
relations  department at (631) 755-5500 or at the Company's  principal executive
offices at 60 Executive Boulevard,  Farmingdale,  New York 11735 requesting such
copies. If a shareholder is receiving  multiple copies of the proxy statement at
the shareholder's household and would like to receive a single copy of the proxy
statement  for a  shareholder's  household  in the future,  shareholders  should
contact their broker,  other nominee  record holder,  or the Company's  investor
relations department to request mailing of a single copy of the proxy statement.

                                       2


            STOCK OWNERSHIP OF PRINCIPAL SHAREHOLDERS AND MANAGEMENT

         Set  forth  below is  information  concerning  stock  ownership  of all
persons  known by the  Company to own  beneficially  5% or more of the shares of
Common Stock of the Company, the executive officers named under "Compensation of
Directors  and  Executive  Officers,"  all  directors,  and  all  directors  and
executive  officers  of  the  Company  as a  group  based  upon  the  number  of
outstanding  shares of Common  Stock as of the close of  business  on the Record
Date. Except as otherwise  indicated,  each of the persons named has sole voting
and investment power with respect to the shares shown.




NAME AND ADDRESS OF                          AMOUNT AND NATURE OF              PERCENT
BENEFICIAL OWNER                           BENEFICIAL OWNERSHIP (1)          OF CLASS (2)
----------------                           ------------------------          ------------
                                                                          
Elazar Rabbani, Ph.D.                      2,194,123   (3)                      6.697%
Shahram K. Rabbani                         2,121,587   (4)                      6.476%
Barry W. Weiner                            1,377,147   (5)                      4.203%
Dean Engelhardt, Ph.D.                       240,783   (6)                        *
Norman E. Kelker, Ph.D.                      167,518   (7)                        *
John J. Delucca                               80,324   (8)                        *
Irwin C. Gerson                               54,690   (9)                        *
Melvin F. Lazar, CPA                          65,394  (10)                        *
John B. Sias                                 184,430  (11)                        *
Marcus Conant, M.D.                           18,583  (12)                        *
J. Morton Davis                            2,843,676  (13)                      8.8%
Citigroup Global Markets Inc., Smith       4,428,213  (14)                      13.7%
Barney Fund Management LLC
All directors and executive officers as    6,880,826  (16)                     20.071%
a group (13 persons) (15)


* Less than 1%.

(1)      Except as otherwise  noted, all shares of Common Stock are beneficially
         owned and the sole  investment  and voting power is held by the persons
         named,  and  such  persons'  address  is c/o  Enzo  Biochem,  Inc.,  60
         Executive Boulevard, Farmingdale, New York 11735.

(2)      Based upon 32,293,757 shares of Common Stock of the Company outstanding
         as of the close of business on the Record Date.

(3)      Includes (i) 468,217  shares of Common Stock issuable upon the exercise
         of options which are  exercisable  within 60 days from the date hereof,
         (ii) 3,469  shares of Common  Stock held in the name of Dr.  Rabbani as
         custodian  for certain of his children and (iii) 2,168 shares of Common
         Stock held in the name of Dr.  Rabbani's  wife as custodian for certain
         of their  children.  Does not  include  55,125  shares of Common  Stock
         issuable upon the exercise of options which are not exercisable  within
         60 days from the date  hereof.  Includes  3,522  shares of Common Stock
         held in the Company's 401(k) plan.

                                       3


(4)      Includes (i) 468,217  shares of Common Stock issuable upon the exercise
         of options which are  exercisable  within 60 days from the date hereof,
         (ii) 614 shares of Common Stock held in the name of Mr.  Rabbani's  son
         and (iii)  1,671  shares  of Common  Stock  that Mr.  Rabbani  holds as
         custodian for certain of his nephews. Does not include 55,125 shares of
         Common  Stock  issuable  upon the  exercise  of  options  which are not
         exercisable within 60 days from the date hereof.  Includes 3,522 shares
         of Common Stock held in the Company's 401(k) plan.

(5)      Includes (i) 468,217  shares of Common Stock issuable upon the exercise
         of options  which are  exercisable  within 60 days from the date hereof
         and (ii)  3,642  shares  of Common  Stock  which  Mr.  Weiner  holds as
         custodian for certain of his children.  Does not include  55,125 shares
         of Common Stock  issuable  upon the  exercise of options  which are not
         exercisable within 60 days from the date hereof.  Includes 3,529 shares
         of Common Stock held in the Company's 401(k) plan.

(6)      Includes  64,117  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof. Does
         not include 8,269 shares of Common Stock  issuable upon the exercise of
         options which are not exercisable  within 60 days from the date hereof.
         Includes  4,765  shares of Common  Stock held in the  Company's  401(k)
         plan.

(7)      Includes  52,852  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof. Does
         not include 5,513 shares of Common Stock  issuable upon the exercise of
         options which are not exercisable  within 60 days from the date hereof.
         Includes  3,438  shares of Common  Stock held in the  Company's  401(k)
         plan.

(8)      Includes  80,324  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof.

(9)      Includes  54,690  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof.

(10)     Includes  28,644  shares of Common Stock  issuable upon the exercise of
         options  which are  exercisable  within  60 days from the date  hereof.
         Includes  7,875  shares of Common  Stock owned by Mr.  Lazar's wife and
         3,150 shares of Common Stock held in the name of a defined benefit plan
         for which Mr. Lazar is the sole trustee and beneficiary.

(11)     Includes  99,947  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof.

(12)     Includes  18,583  shares of Common Stock  issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof. Does
         not include 7,875 shares of Common Stock  issuable upon the exercise of
         options which are not exercisable within 60 days from the date hereof.

(13)     Mr. Davis' address is D.H.  Blair  Investment  Banking  Corp.,  44 Wall
         Street, New York, New York 10005. Includes (i) 30,525 owned directly by
         Mr. Davis,  (ii)  1,416,052  shares of Common Stock owned by D.H. Blair
         Investment  Banking Corp.  of which Mr. Davis is the sole  shareholder,
         (iii)  720,870  shares owned by Rosalind  Davidowitz,  Mr. Davis' wife,
         (iv) 663,446  shares of Common Stock owned by Engex,  Inc., a close-end
         registered investment company of which Mr. Davis is the Chairman of the
         Board of  Directors,  and (v)  12,733  shares  owned  by an  investment
         advisor whose principal is Mr. Davis.  This information is based solely
         on Amendment No. 4 to a Schedule 13G filed on February 9, 2005.

(14)     The  address  of Smith  Barney is 333 West 34th  Street,  New York,  NY
         10036, and the address of Citigroup Inc. is 399 Park Avenue,  New York,
         New York 10001, the address of Citigroup  Global Holdings,  Inc. is 388
         Greenwich  Street,  New York, New York 10001. This information is based
         solely on Amendment No. 4 to Schedule 13G filed on February 14, 2005.

                                       4


(15)     The total number of directors and executive officers includes three (3)
         executive officers who were not named under  "Compensation of Directors
         and Executive Officers."

(16)     Includes 1,989,471 shares of Common Stock issuable upon the exercise of
         options which are exercisable within 60 days from the date hereof. Does
         not include  203,571  shares of Common Stock issuable upon the exercise
         of options held by such individuals which are not exercisable within 60
         days from the date hereof.

                                   PROPOSAL 1
                              ELECTION OF DIRECTORS

         The Company has three (3) staggered classes of Directors, each of which
serves for a term of three (3) years. At the Annual Meeting, the Company's Class
III  Directors  will be elected to hold  office for a term of three (3) years or
until their  respective  successors are elected and qualified.  Unless otherwise
instructed, the accompanying form of proxy will be voted for the election of the
below-listed  nominees all of whom currently  serve as Class III  Directors,  to
continue  such  service  as Class  III  Directors.  Management  has no reason to
believe  that any of the  nominees  will not be a candidate or will be unable to
serve as a  director.  However,  in the event that the  nominees  should  become
unable or unwilling to serve as  directors,  the form of proxy will be voted for
the election of such persons as shall be  designated by the Class I and Class II
Directors.

                   CLASS III DIRECTOR NOMINEES TO SERVE UNTIL
                      THE 2009 ANNUAL MEETING, IF ELECTED:

                      CLASS III: NEW TERM TO EXPIRE IN 2009

NAME                              AGE               YEAR FIRST BECAME A DIRECTOR
----                              ---               ----------------------------
Elazar Rabbani, Ph.D.              61                           1976
John B. Sias                       78                           1982
Marcus A. Conant, M.D.             70                           2004

         THE BOARD OF  DIRECTORS  OF THE  COMPANY  RECOMMENDS  A VOTE  "FOR" THE
ELECTION  OF  THE  ABOVE-NAMED  NOMINEES.  PROXIES  SOLICITED  BY THE  BOARD  OF
DIRECTORS  WILL BE SO VOTED  UNLESS  SHAREHOLDERS  SPECIFY  IN THEIR  PROXIES  A
CONTRARY CHOICE.

                     DIRECTORS WHO ARE CONTINUING IN OFFICE:

                         CLASS I: TERM TO EXPIRE IN 2007

NAME                              AGE               YEAR FIRST BECAME A DIRECTOR
----                              ---               ----------------------------
Shahram Rabbani                    53                           1976
Irwin C. Gerson                    75                           2001

                        CLASS II: TERM TO EXPIRE IN 2008

NAME                              AGE               YEAR FIRST BECAME A DIRECTOR
----                              ---               ----------------------------
Barry W. Weiner                   55                            1977
John J. Delucca                   62                            1982
Melvin F. Lazar, CPA              66                            2002

                                       5


                        DIRECTORS AND EXECUTIVE OFFICERS

         The directors and executive  officers of the Company are  identified in
the table below. Each executive officer of the Company serves at the pleasure of
the Board of Directors.



                                                        YEAR BECAME A
                                                         DIRECTOR OR
NAME                                    AGE            EXECUTIVE OFFICER     POSITION
----                                    ---            -----------------     --------
                                                                    
Elazar Rabbani, Ph.D.                   61                    1976           Chairman of the Board of Directors
                                                                             and Chief Executive Officer
Shahram K. Rabbani                      53                    1976           Chief Operating Officer, Treasurer,
                                                                             Secretary and Director
Barry W. Weiner                         55                    1977           President, Chief Financial Officer
                                                                             and Director
Dean Engelhardt, Ph.D.                  65                    1981           Executive Vice President
Norman E. Kelker, Ph.D                  66                    1981           Senior Vice President
Herbert B. Bass                         57                    1995           Vice President of Finance
Barbara E. Thalenfeld, Ph.D.            65                    1995           Vice President, Corporate Development
David C. Goldberg                       48                    1995           Vice President, Business Development
John J. Delucca                         62                    1982           Director
John B. Sias                            78                    1982           Director
Irwin C. Gerson                         75                    2001           Director
Melvin F. Lazar, CPA                    66                    2002           Director
Marcus A. Conant, M.D.                  70                    2004           Director


BIOGRAPHICAL INFORMATION REGARDING DIRECTORS AND EXECUTIVE OFFICERS

         DR. ELAZAR RABBANI is one of Enzo Biochem's  founders and has served as
the  Company's  Chairman of the Board of Directors and Chief  Executive  Officer
since its  inception  in 1976.  Dr.  Rabbani has  authored  numerous  scientific
publications  in the field of molecular  biology,  in  particular,  nucleic acid
labeling and  detection.  He is also the lead  inventor of many of the company's
pioneering  patents  covering a wide range of  technologies  and  products.  Dr.
Rabbani  received  his  Bachelor  of Arts  degree  from New York  University  in
Chemistry and his Ph.D. in Biochemistry from Columbia University. He is a member
of the American Society for Microbiology.

         SHAHRAM K. RABBANI is the Chief Operating Officer, Treasurer, Secretary
and Director, is a founder and has been with the Company since its inception. He
is also  President of Enzo Clinical  Labs.  Mr.  Rabbani  serves on the New York
State Clinical  Laboratory  Association,  a professional board. Mr. Rabbani is a
trustee of Adelphi University and serves as Chairman of its Audit Committee.  He
received a Bachelor of Arts Degree in Chemistry from Adelphi University, located
in Long Island, New York.

         BARRY W. WEINER President,  Chief Financial Officer and Director,  is a
founder of the Company. He has served as the Company's President since 1996, and
previously held the position of Executive Vice President.  Before his employment
with Enzo,  he worked in  several  managerial  and  marketing  positions  at the
Colgate  Palmolive   Company.   Mr.  Weiner  is  a  Director  of  the  New  York
Biotechnology Association.  He received his Bachelor of Arts degree in Economics
from New York University and a Master of Business Administration in Finance from
Boston University.

         DR. DEAN  ENGELHARDT has been the Company's  Executive Vice  President,
since July 2000.  Since  joining the Company in 1981,  Dr.  Engelhardt  has held
several  other  executive  and  scientific  positions  within Enzo  Biochem.  In
addition,  Dr.  Engelhardt  has authored many papers in the area of nucleic acid
synthesis and protein  production and has been a featured  presenter at numerous
scientific  conferences  and  meetings.  He holds a Ph.D.  degree  in  Molecular
Genetics from Rockefeller University.

                                       6


         DR.  NORMAN E.  KELKER is the Senior Vice  President  and has held this
position  since 1989.  Before this,  he was the  Company's  Vice  President  for
Scientific  Affairs.  Dr.  Kelker has authored  numerous  scientific  papers and
presentations in the biotechnology  field. He is a member of American Society of
Microbiology  and the American  Association of the  Advancement of Science.  Dr.
Kelker received his Ph.D. in Microbiology  and Public Health from Michigan State
University.

         HERBERT B. BASS is the  Company's  Vice  President  of Finance  for the
Company and is also Senior Vice  President  of Enzo  Clinical  Labs.  Before his
promotion in 1989 to Vice President of Finance, Mr. Bass served as the Corporate
Controller of the Company.  Mr. Bass has been with the Company since 1986.  From
1977 to 1986,  Mr.  Bass  held  various  positions  at  Danziger  and  Friedman,
Certified Public  Accountants,  the most recent of which was audit manager.  For
the  preceding  seven years,  he held various  positions at Berenson & Berenson,
Certified  Public  Accountants.   Mr.  Bass  received  a  Bachelor  of  Business
Administration  degree in Accounting from Bernard M. Baruch College, in New York
City.

         DR.   BARBARA  E.   THALENFELD  is  the  Vice  President  of  Corporate
Development  for Enzo Biochem and Vice  President  of Clinical  Affairs for Enzo
Therapeutics  and has been employed with the Company since 1982. Dr.  Thalenfeld
has authored  numerous  scientific  papers in the areas of molecular biology and
genetics,  and is a member of the  American  Society of Gene  Therapy,  the Drug
Development  Association and the Association of Clinical Research Professionals.
Dr.  Thalenfeld  received her Ph.D. at the Institute of  Microbiology  at Hebrew
University in Jerusalem and a Master of Science degree in Biochemistry from Yale
University,  and  completed a Post  Doctoral  Fellowship  in the  Department  of
Biological Sciences at Columbia University.

         DAVID C.  GOLDBERG is the Vice  President of Business  Development  for
Enzo Biochem and Senior Vice  President of Enzo Clinical Labs, has been employed
with the company since 1985.  He has held several  managerial  positions  within
Enzo Biochem.  Mr.  Goldberg also held  management and marketing  positions with
DuPont-NEN and Gallard  Schlesinger  Industries  before joining the Company.  He
received a Master of Science degree in Microbiology from Rutgers  University and
a Master of Business Administration in Finance from New York University.

         JOHN B. SIAS has been a Director of the Company since January 1982. Mr.
Sias was President and Chief Executive Officer of Chronicle  Publishing  Company
from April 1993 to September  2000. From January 1986 until April 1993, Mr. Sias
was President of ABC Network Division, Capital Cities/ABC,  Inc. From 1977 until
January 1986, he was the Executive Vice  President,  President of the Publishing
Division   (which   includes   Fairchild   Publications)   of   Capital   Cities
Communications, Inc.

         JOHN J.  DELUCCA has been a Director of the  Company  since 1982.  From
2003 to 2004,  Mr.  Delucca was Executive  Vice  President  and Chief  Financial
Officer  of REL  Consulting  Group.  Mr.  Delucca  had been the Chief  Financial
Officer & Executive Vice President, Finance & Administration of Coty, Inc., from
1999 to 2002.  From 1993 until 1999, he was Senior Vice  President and Treasurer
of RJR Nabisco,  Inc. From 1992 until 1993,  he was managing  director and Chief
Financial Officer of Hascoe Associates, Inc. From 1990 to 1992, he was President
of  The   Lexington   Group.   From  1989  until   1990,   he  was  Senior  Vice
President-Finance  of the Trump Group.  From 1986 until 1989, he was senior Vice
President-Finance at International Controls Corp. From 1985 until 1986, he was a
Vice  President  and  Treasurer  of Textron,  Inc.  Before  that,  he was a Vice
President and Treasurer of the Avco Corporation, which was acquired by Textron.

         IRWIN C. GERSON has been a Director  of the Company  since May 8, 2001.
From 1995 until  December  1998,  Mr.  Gerson served as Chairman of Lowe McAdams
Healthcare and prior thereto had been, since 1986,  Chairman and Chief Executive
Officer  of  William  Douglas  McAdams,  Inc.,  one of the  largest  advertising
agencies in the U.S. specializing in pharmaceutical marketing and communications
to healthcare professionals.  In February 2000, he was inducted into the Medical
Advertising  Hall of Fame. Mr. Gerson has a Bachelor of Science in Pharmacy from
Fordham  University  and an  MBA  from  the  NYU  Graduate  School  of  Business
Administration.  He is a director of Andrx Corporation,  a NASDAQ listed company
which specializes in proprietary drug delivery technologies.  From 1990 to 1999,
he was  Chairman of the Council of  Overseers  of the Arnold and Marie  Schwartz
College  of  Pharmacy  and has  served as a trustee  of The  Albany  College  of
Pharmacy and Long Island University.

                                       7


         MELVIN F. LAZAR,  CPA has been a Director of the Company  since  August
2002 and was appointed Lead Independent  Director on October 31, 2005. Mr. Lazar
was a founding  partner of the public  accounting firm of Lazar,  Levine & Felix
(LLP) from 1969 until October  2002.  Mr. Lazar and his firm served the business
and  legal  communities  for over 30  years.  He is an  expert  on the  topic of
business valuations and merger and acquisition activities.  Mr. Lazar is a board
member  and  chairman  of the  audit  committee  of  Arbor  Realty  Trust,  Inc.
(ABR:NYSE).  Arbor is a real estate  investment trust (REIT) formed to invest in
real estate related bridge and mezzanine loans, preferred equity investments and
other real estate related assets.  Mr. Lazar is a board member and serves as the
Chairman of the Audit Committee of privately owned Active Media Services,  Inc.,
the largest  corporate barter company in the nation.  Mr. Lazar holds a Bachelor
of  Business  Administration  degree from The City  College of New York  (Baruch
College).

         MARCUS A. CONANT, M.D. has been a Director of the Company since July 1,
2004. Dr. Conant,  received his B.S. and M.D. degrees from Duke  University.  He
was an exchange student at Hammersmith  Hospital in London,  England and held an
Elective Fellowship in Biochemistry at the London Hospital.  Dr. Conant has been
the recipient of numerous awards, and has served as a member of or consultant to
a broad array of scientific societies and associations,  community organizations
and government committees and has authored or co-authored more than 70 published
papers.  Dr. Conant is a Clinical  Professor at the University of California San
Francisco  (UCSF) and has been on the faculty of UCSF since 1967.  He  currently
serves as Chairman of the Board of the Conant Foundation,  an HIV/AIDS education
and research  foundation based in San Francisco.  Dr. Conant served as principal
investigator  for Enzo's Phase I clinical  trial of its gene  medicine for HIV-1
infection.

         Dr.  Elazar  Rabbani and Shahram K.  Rabbani are  brothers and Barry W.
Weiner is their brother-in-law.

         John J.  Delucca,  John B. Sais,  Irwin C. Gerson,  Melvin F. Lazar and
Marcus  A.  Conant  qualify  as  "independent   directors"  under  the  criteria
established by the New York Stock Exchange.

                              CORPORATE GOVERNANCE

         Our Board of Directors  and  management  are  committed to  responsible
corporate  governance  to ensure that the  Company is managed for the  long-term
benefit of its  shareholders.  To that end,  during  the past year,  as in prior
years,  the Board of Directors and  management  have  periodically  reviewed and
updated,  as  appropriate,  the  Company's  corporate  governance  policies  and
practices.  During the past year,  the Board has also continued to evaluate and,
when  appropriate,  update  the  Company's  corporate  governance  policies  and
practices in accordance with the requirements of the  Sarbanes-Oxley Act of 2002
and the rules  and  listing  standards  issued by the  Securities  and  Exchange
Commission and the New York Stock Exchange ("NYSE").

CORPORATE GOVERNANCE POLICIES AND PRACTICES

         The  Company has  instituted  a variety of policies  and  practices  to
foster and maintain responsible corporate governance, including the following:

         CORPORATE  GOVERNANCE  GUIDELINES  - The  Board  of  Directors  adopted
         Corporate Governance Guidelines,  which collect in one document many of
         the corporate governance practices and procedures that had evolved over
         the  years.  These  guidelines  address  the  duties  of the  Board  of
         Directors,   director   qualifications  and  selection  process,  Board
         operations,  Board  committee  matters and  continuing  education.  The
         guidelines  also provide for annual  self-evaluations  by the Board and
         its committees.  The Board reviews these guidelines on an annual basis.
         The guidelines are available on the Company's website at www.enzo.com.

         CORPORATE  CODE OF  ETHICS  - The  Company  has a Code of  Ethics  that
         applies to all of the Company's employees,  officers and members of the
         Board.  The Code of Ethics is  available  on the  Company's  website at
         www.enzo.com.

         BOARD COMMITTEE  CHARTERS - Each of the Company's  Audit,  Compensation
         and  Nominating/Governance  Committees has a written charter adopted by
         the  Company's  Board  of  Directors  that  establishes  practices  and
         procedures for such committee in accordance with  applicable  corporate
         governance  rules and  regulations.  The charters are  available on the
         Company's website at WWW.ENZO.COM.

                                       8


         LEAD  INDEPENDENT  DIRECTOR CHARTER - On October 31, 2005, the Board of
         Directors voted to create the position of Lead Independent  Director of
         the  Board of  Directors,  to elect  Melvin  F.  Lazar to serve as Lead
         Independent  Director,  effective  immediately,  and  to  adopt  a Lead
         Independent  Director  Charter.  See  below  for a  description  of the
         responsibilities of the Lead Independent Director. The Lead Independent
         Director Charter is available on the Company's website at www.enzo.com.

         DIRECTOR INDEPENDENCE

                  REQUIREMENTS  -  The  Board  of  Directors   believes  that  a
                  substantial  majority  of its members  should be  independent,
                  non-employee  directors.   The  Board  adopted  the  following
                  "Director  Independence  Standards," which are consistent with
                  criteria established by the New York Stock Exchange, to assist
                  the Board in making these independence determinations.

                  No  Director  can  qualify as  independent  if he or she has a
                  material  relationship  with the Company outside of his or her
                  service  as a  Director  of the  Company.  A  Director  is not
                  independent if, within the preceding three years:


                           o        The director was an employee of the Company.

                           o        An immediate  family  member of the director
                                    was an executive officer of the Company.

                           o        A director was  affiliated  with or employed
                                    by a present or former  internal or external
                                    auditor of the Company.

                           o        An immediate family member of a director was
                                    affiliated    with   or    employed   in   a
                                    professional capacity by a present or former
                                    internal or external auditor of the Company.

                           o        A director, or an immediate family member of
                                    the  director,  received  more than $100,000
                                    per  year in  direct  compensation  from the
                                    Company,  other than  director and committee
                                    fees and  pension or other forms of deferred
                                    compensation  for prior  services  (provided
                                    such  compensation  is not contingent in any
                                    way on continued service).

                           o        The director,  or an immediate family member
                                    of  the   director,   was   employed  as  an
                                    executive  officer of another  company where
                                    any of the  Company's  executives  served on
                                    that company's compensation committee of the
                                    board of directors.

                           o        The  director  was an  executive  officer or
                                    employee,  or an immediate  family member of
                                    the director was an  executive  officer,  of
                                    another  company  that made  payments to, or
                                    received  payments  from,  the  Company  for
                                    property or services in an amount which,  in
                                    any single fiscal year, exceeded the greater
                                    of $1  million or two  percent  (2%) of such
                                    other company's consolidated gross revenues.

                           o        The director,  or an immediate family member
                                    of the director, was an executive officer of
                                    another  company  that was  indebted  to the
                                    company,   or  to  which  the   Company  was
                                    indebted,  where the total  amount of either
                                    company's

                                       9


                                    indebtedness  to the other was five  percent
                                    (5%)  or  more  of  the  total  consolidated
                                    assets of the company he or she served as an
                                    executive officer.

                           o        The director,  or an immediate family member
                                    of the director, was an officer, director or
                                    trustee of a charitable  organization  where
                                    the    Company's    annual     discretionary
                                    charitable  contributions  to the charitable
                                    organization  exceeded  the  greater  of  $1
                                    million  or  five   percent   (5%)  of  that
                                    organization's consolidated gross revenues.


                  The  Board  has  reviewed  all   material   transactions   and
                  relationships  between each director,  or any member of his or
                  her immediate family,  and the Company,  its senior management
                  and its  independent  auditors.  Based on this  review  and in
                  accordance with its independence standards outlined above, the
                  Board of Directors has  affirmatively  determined  that all of
                  the non-employee directors are independent.

         BOARD NOMINATION POLICIES AND PROCEDURE

                  -        NOMINATION  PROCEDURE  -  The   Nominating/Governance
                  Committee is  responsible  for  identifying,  evaluating,  and
                  recommending  candidates  for election to the Board,  with due
                  consideration for recommendations made by other Board members,
                  the CEO,  shareholders,  and other sources. In addition to the
                  above  criteria,  the  Nominating/Governance   Committee  also
                  considers the appropriate  balance of experience,  skills, and
                  characteristics  desirable among the members of the board. The
                  independent     members    of    the    Board    review    the
                  Nominating/Governance   Committee   candidates   and  nominate
                  candidates for election by the Company shareholders.

                  Directors   must  also   possess  the  highest   personal  and
                  professional ethics,  integrity and values and be committed to
                  representing  the  long-term  interests  of all  shareholders.
                  Board members are expected to diligently  prepare for,  attend
                  and   participate  in  all  Board  and  applicable   Committee
                  meetings.  Each Board  member is expected to ensure that other
                  existing and future  commitments do not  materially  interfere
                  with the member's service as a director.

                  The  Nominating/Governance  Committee  also reviews  whether a
                  potential  candidate  will  meet  the  Company's  independence
                  standards  and any  other  director  or  committee  membership
                  requirements  imposed  by law,  regulation  or stock  exchange
                  rules.

                  Director  candidates  recommended to the Committee are subject
                  to  full  Board  approval  and  subsequent   election  by  the
                  shareholders.  The Board of Directors is also  responsible for
                  electing  directors to fill  vacancies on the Board that occur
                  due to  retirement,  resignation,  expansion  of the  Board or
                  other reasons between the Shareholders'  annual meetings.  The
                  Nominating/Governance Committee may retain a recruitment firm,
                  from time to time,  to assist in  identifying  and  evaluating
                  director  candidates.  When  a firm  is  used,  the  Committee
                  provides specified criteria for director candidates,  tailored
                  to the  needs of the Board at that  time,  and pays the firm a
                  fee for these services.  Suggestions  for director  candidates
                  are also received from board members and management and may be
                  solicited from professional associations as well.

         BOARD COMMITTEES

                  -        All members of each of the Company's  three  standing
                  committees  -  the  Audit,   Compensation,   and   Nominating/
                  Governance - are required to be independent in accordance with
                  NYSE   criteria.   See   below  for  a   description   of  the
                  responsibilities of the Board's standing committees.

                                       10


         EXECUTIVE SESSIONS OF NON-MANAGEMENT DIRECTORS

                  -        The   Board   and   the   Audit,   Compensation   and
                  Nominating/Governance Committees periodically hold meetings of
                  only the  independent  directors or Committee  members without
                  management  present.  The presiding  director of the Executive
                  Sessions  is  rotated  among the  independent,  non-management
                  directors.

         LEAD INDEPENDENT DIRECTOR

                  -        The duties of the Lead Independent  Director,  as set
                  forth in the Lead Independent  Director  Charter,  among other
                  things,  are to develop  the agendas for and serve as chairman
                  of the executive sessions of the independent  directors of the
                  Company;  serve as principal  liaison  between the independent
                  directors  of the  Company  and the  Chairman of the Board and
                  between  the  independent  directors  and  senior  management;
                  provide  the  Chairman  of  the  Board  with  input  as to the
                  preparation  of the  agendas  for Board  meetings;  advise the
                  Chairman  of  the  Board  as  to  the  quality,  quantity  and
                  timeliness  of the  information  submitted  by  the  Company's
                  management   that  is   necessary  or   appropriate   for  the
                  independent  directors to effectively and responsibly  perform
                  their duties;  ensure that independent directors have adequate
                  opportunities to meet and discuss issues in executive sessions
                  without  management  present;  if the Chairman of the Board is
                  unable to attend a Board of Directors meeting, act as chairman
                  of such Board of  Directors  meeting;  and perform  such other
                  duties  as the  Board of  Directors  shall  from  time to time
                  delegate.  On October 31, 2005, the Board of Directors elected
                  Melvin  F.  Lazar to serve as the Lead  Independent  Director,
                  effective immediately.

         BOARD ACCESS TO INDEPENDENT ADVISORS

                  -        The  Board  as  a  whole,   and  each  of  the  Board
                  committees separately,  have authority to retain and terminate
                  such  independent  consultants,  counselors or advisors to the
                  Board as each shall deem necessary or appropriate.

         SHAREHOLDER COMMUNICATIONS WITH BOARD OF DIRECTORS

                  -        DIRECT  COMMUNICATIONS - Any shareholder  desiring to
                  communicate  with the Board of  Directors or with any director
                  regarding  the Company may write to the Board or the director,
                  c/o Shahram K. Rabbani, Office of the Secretary, Enzo Biochem,
                  Inc.,  60  Executive  Boulevard,  Farmingdale,  NY 11735.  The
                  Office of the Secretary  will forward all such  communications
                  to the  director(s).  Shareholders may also submit an email by
                  filling  out  the  email  form  on the  Company's  website  at
                  www.enzo.com.

                  -        ANNUAL MEETING - The Company encourages its directors
                  to attend the annual  meeting of  shareholders  each year. Dr.
                  Elazar Rabbani and Messrs. Melvin F. Lazar, Shahram K. Rabbani
                  and Barry W. Weiner and Marcus A. Conant  attended  the Annual
                  Meeting of Shareholders held in January 2005.

         MEETINGS OF THE BOARD OF DIRECTORS AND ITS COMMITTEES

         During  the  fiscal  year  ended  July 31,  2005,  there  were 5 formal
meetings of the Board of  Directors,  several  actions by unanimous  consent and
several   informal   meetings.   Currently,   the  Board  of  Directors   has  a
Nominating/Governance   Committee,   an  Audit   Committee  and  a  Compensation
Committee. The Nominating/Governance Committee had one formal meeting, the Audit
Committee  had seven formal  meetings and the  Compensation  Committee had three
formal meetings.

         The Audit Committee was established by and among the Board of Directors
for the purpose of overseeing the accounting and financial  reporting  processes
of the  Company  and  audits  of the  financial  statements  of the  Company  in
accordance with Section  3(a)(58)(A) of the Securities  Exchange Act of 1934, as
amended, The Audit

                                       11


Committee is authorized to review proposals of the Company's  auditors regarding
annual  audits,  recommend the  engagement or discharge of the auditors,  review
recommendations  of  such  auditors  concerning  accounting  principles  and the
adequacy of internal  controls and accounting  procedures and practices,  review
the scope of the annual audit,  approve or disapprove each professional  service
or type of service other than standard  auditing  services to be provided by the
auditors,  and review and  discuss  the audited  financial  statements  with the
auditors.  The  current  members of the Audit  Committee  are  Messrs.  Delucca,
Gerson, Lazar and Sias, and Mr. Delucca is the Chairman.  The Board of Directors
has determined  that each of the Audit  Committee  members are  independent,  as
defined in the NYSE's  listing  standards and as defined in Item  7(d)(3)(iv) of
Schedule  14A  under  the  Securities  and  Exchange  Act of 1934.  The Board of
Directors has further determined that Messrs.  Delucca and Lazar are each "audit
committee  financial  experts" as such term is defined  under Item  401(h)(2) of
Regulation S-K.

         The Compensation Committee has the power and authority to (i) establish
a general compensation policy for the officers and employees of the Corporation,
including to  establish  and at least  annually  review  officers'  salaries and
levels of officers' participation in the benefit plans of the Corporation,  (ii)
prepare any reports that may be required by the  regulations  of the  Securities
and Exchange  Commission or otherwise  relating to officer  compensation,  (iii)
approve any  increases  in  directors'  fees,  (iv) grant stock  options and (v)
exercise  all other  powers of the Board of  Directors  with  respect to matters
involving  the  compensation  of  employees  and the  employee  benefits  of the
Corporation as shall be delegated by the Board of Directors to the  Compensation
Committee. The current members of the Compensation Committee are Messrs. Gerson,
Delucca and Lazar and Mr. Gerson is the Chairman.

         The  Nominating/Governance  Committee has the power to recommend to the
Board of  Directors  prior to each  annual  meeting of the  shareholders  of the
Corporation: (i) the appropriate size and composition of the Board of Directors;
and (ii)  nominees:  (1) for  election  to the Board of  Directors  for whom the
Corporation  should solicit proxies;  (2) to serve as proxies in connection with
the annual shareholders'  meeting; and (3) for election to all committees of the
Board  of  Directors  other  than  the   Nominating/Governance   Committee.  The
Nominating/Governance Committee will consider nominations from the shareholders,
provided  that  they are made in  accordance  with the  Company's  By-laws.  The
current  members of the  Nominating/Governance  Committee  are  Messrs.  Gerson,
Delucca, Lazar and Sias and Mr. Lazar is the Chairman.

AUDIT COMMITTEE REPORT

         In connection with the  preparation and filing of the Company's  Annual
Report on Form 10-K for the year ended July 31, 2005:

                  (1)      The  Audit  Committee   reviewed  and  discussed  the
                  audited financial statements with management;

                  (2)      The Audit  Committee  discussed with the  independent
                  auditors  matters  required to be discussed under Statement on
                  Auditing Standards No. 61, as may be modified or supplemented;

                  (3)      The Audit Committee reviewed the written  disclosures
                  and the letter from the independent  auditors  required by the
                  Independence  Standards  Board  Standard  No.  1,  as  may  be
                  modified or  supplemented,  and discussed with the independent
                  auditors any  relationships  that may impact their objectivity
                  and  independence  and  satisfied  itself as to the  auditors'
                  independence;

                  (4)      The  Audit  Committee  discussed  with the  Company's
                  independent  auditors  the  overall  scope and plans for their
                  audits. The Audit Committee met with the independent auditors,
                  with and without management present, to discuss the results of
                  their   examinations,   their  evaluations  of  the  Company's
                  internal  controls,  and the overall  quality of the Company's
                  financial  reporting.  The Audit  Committee  held four  formal
                  meetings during the fiscal year ended July 31, 2004 and

                  (5)      Based  on the  review  and  discussions  referred  to
                  above,  the  Audit  Committee  recommended  to  the  Board  of
                  Directors that the audited financial statements of the Company
                  be included in the 2005 Annual Report on Form 10-K.

                                       12


                                Submitted by the members of the Audit Committee


                                                  JOHN J. DELUCCA
                                                  IRWIN C. GERSON
                                                  MELVIN F. LAZAR, CPA
                                                  JOHN B. SIAS

                                       13


SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

         Section  16(a) of the  Securities  Exchange  Act of 1934,  as  amended,
requires  the   Company's   executive   officers,   directors  and  persons  who
beneficially  own more than 10% of a registered  class of the  Company's  equity
securities  (collectively,  "Reporting Persons") to file with the Securities and
Exchange  Commission  initial  reports of  ownership  and  reports of changes in
ownership  of common  stock and other equity  securities  of the  Company.  Such
executive  officers,  directors  and  greater  than 10%  beneficial  owners  are
required by Securities and Exchange Commission regulation to furnish the Company
with copies of all Section 16(a) forms filed by such reporting persons.

         Based  solely on the  Company's  review of such forms  furnished to the
Company and written  representations from certain reporting persons, the Company
believes that the Reporting  Persons have  complied with all  applicable  filing
requirements.

CERTAIN RELATIONSHIP AND RELATED TRANSACTIONS

         Enzo Clinical  Labs,  Inc.  ("Enzolabs"),  a subsidiary of the Company,
leases a  facility  located  in  Farmingdale,  New  York  from  Pari  Management
Corporation  ("Pari").  Pari is owned equally by Elazar Rabbani,  Ph.D., Shahram
Rabbani and Barry Weiner and his wife,  the officers and directors of Pari.  The
lease originally commenced on December 20, 1989, but was amended and extended in
March 2005 and now  terminates on March 31, 2017.  During fiscal 2005,  Enzolabs
paid approximately  $1,375,283 (including $153,625 in real estate taxes) to Pari
with respect to such facility and future  payments are subject to cost of living
adjustments.  The Company,  which has guaranteed  Enzolabs'  obligations to Pari
under the lease,  believes that the existing lease terms are as favorable to the
Company as would be available from an unaffiliated party.

CODE OF ETHICS

         The  Company  has  adopted a Code of Ethics (as such term is defined in
Item 406 of  Regulation  S-K),  which  code has been  filed as Exhibit 14 to the
Company's  annual  report on Form 10-K for the fiscal year ended July 31,  2003.
The Code of Ethics applies to the Company's  Executive Officer,  Chief Financial
Officer and principal  accounting  officer or controller,  or persons performing
similar functions.  The Code of Ethics has been designed to deter wrongdoing and
to promote:

(1)      Honest and ethical conduct, including the ethical handling of actual or
         apparent  conflicts  of  interest  between  personal  and  professional
         relationships;

(2)      Full, fair, accurate,  timely, and understandable disclosure in reports
         and  documents  that  the  Company  files  with,  or  submits  to,  the
         Securities and Exchange  Commission and in other public  communications
         made by the Company;

(3)      Compliance with applicable governmental laws, rules and regulations;

(4)      The prompt internal reporting or violations of the Code of Ethics to an
         appropriate person or persons identified in the Code of Ethics; and

(5)      Accountability for adherence to the Code of Ethics.

                                       14


                COMPENSATION OF DIRECTORS AND EXECUTIVE OFFICERS

         The  following  summary  compensation  table sets  forth the  aggregate
compensation  paid by the  Company  to its chief  executive  officer  and to the
Company's  four other most highly  compensated  executive  officers whose annual
compensation  exceeded $100,000 for the fiscal year ended July 31, 2005 (each, a
"Named  Executive  Officer") for services during the fiscal years ended July 31,
2005, 2004 and 2003:

                           SUMMARY COMPENSATION TABLE



                                                                                                LONG TERM
                                                                                               COMPENSATION
                                                                                                  AWARDS
                                                                                                  ------

               NAME AND                                        ANNUAL COMPENSATION
          PRINCIPAL POSITION                                   -------------------                SECURITIES
          ------------------                                                                      UNDERLYING
                                              YEAR          SALARY ($)        BONUS ($)         OPTIONS/SARS (#)
                                              ----          ----------        ---------         ----------------
                                                                                         
Elazar Rabbani, Ph.D.,                        2005           $442,200         $283,250               50,000
   CHAIRMAN OF THE BOARD OF                   2004           $430,942         $275,000               78,750
   DIRECTORS AND CEO                          2003           $402,963         $275,000              105,000

Shahram K. Rabbani,                           2005           $405,423         $267,800               50,000
   CHIEF OPERATING OFFICER,                   2004           $395,046         $260,000               78,750
   TREASURER, SECRETARY AND                   2003           $367,825         $260,000              105,000
   DIRECTOR

Barry W. Weiner,                              2005           $405,423         $267,800               50,000
   PRESIDENT, CHIEF FINANCIAL                 2004           $395,046         $260,000               78,750
   OFFICER AND DIRECTOR                       2003           $367,825         $260,000              105,000

Dean Engelhardt, Ph.D.,                       2005           $231,624          $55,000               10,000
   EXECUTIVE VICE PRESIDENT                   2004           $225,737          $55,000               15,750
                                              2003           $221,622          $55,000               15,750

Norman E. Kelker, Ph.D.,                      2005           $200,104          $45,000               10,000
   SENIOR VICE PRESIDENT                      2004           $202,476          $45,000               15,750
                                              2003           $183,268          $45,000               10,500



                      OPTION/SAR GRANTS IN LAST FISCAL YEAR

                                                   INDIVIDUAL GRANTS



                                                      PERCENT OF                                POTENTIAL REALIZABLE
                                         NUMBER OF       TOTAL                                    VALUE AT ASSUMED
                                        SECURITIES    OPTIONS/SARS                             ANNUAL RATES OF STOCK
                                        UNDERLYING     GRANTED TO   EXERCISE OF                PRICE APPRECIATION FOR
                                        OPTION/SARS   EMPLOYEES IN   BASE PRICE   EXPIRATION       OPTIONS TERM
                NAME                    GRANTED (#)    FISCAL YEAR   ($ / SH)        DATE        5% ($)     10% ($)
                ----                    -----------    -----------   --------        ----        ------     -------
                                                                                        
Elazar Rabbani, Ph.D., Chairman of        50,000        11.575%       $17.66      01/21/2015   $555,314   $1,407,275
     the Board of Directors and Chief
     Executive Officer
Shahram K. Rabbani, Chief Operating       50,000        11.575%       $17.66      01/21/2015   $527,643   $1,407,275
     Officer, Treasurer, Secretary and
     Director
Barry W. Weiner, President and Director   50,000        11.575%       $17.66      01/21/2015   $527,643   $1,407,275
Dean Engelhardt, Ph.D., Executive Vice    10,000         2.315%       $17.66      01/21/2015   $111,063     $281,455
     President
Norman Kelker, Ph.D., Senior Vice         10,000         2.315%       $17.66      01/21/2015   $111,063     $281,455
     President


                                       15


AGGREGATED  OPTION/SAR  EXERCISES  IN  LAST  FISCAL  YEAR  AND  FISCAL  YEAR-END
OPTION/SAR VALUES

         The  following  table sets forth  certain  information  with respect to
stock option  exercises by the Named  Executive  Officers during the fiscal year
ended July 31, 2005 and the value of unexercised  options held by them at fiscal
year-end.



                                                         NUMBER OF SECURITIES           VALUE OF UNEXERCISED
                                                        UNDERLYING UNEXERCISED      IN-THE-MONEY OPTIONS/SARS AT
                                                       OPTIONS/SARS OPTIONS AT         FISCAL YEAR-END ($) (1)
                                                         FISCAL YEAR-END (#)           -----------------------
                                                         -------------------
                              SHARES
                           ACQUIRED ON      VALUE
NAME                       EXERCISE (#)  REALIZED ($)  EXERCISABLE  UNEXERCISABLE     EXERCISABLE     UNEXERCISABLE
----                       ------------  ------------  -----------  -------------     -----------     -------------
                                                                                       
Elazar Rabbani, Ph.D.            0            $0         535,221       55,125         $2,723,090         $249,998
Shahram K. Rabbani               0            $0         535,221       55,125         $2,723,090         $249,998
Barry W. Weiner                  0            $0         535,221       55,125         $2,723,090         $249,998
Dean Engelhardt, Ph.D.         7,036        $69,938       84,218        8,268         $  369,994         $ 37,500
Norman E. Kelker, Ph.D.        7,036        $69,938       52,852        5,512         $  220,900         $ 25,000


(1)  Market  value of the  underlying  securities  at fiscal  year end minus the
     exercise price paid in cash or stock.

         On  June  3,  2005  the  Board  of  Directors  unanimously  approved  a
resolution to  immediately  accelerate the  effectiveness  of all unvested stock
options that were "out of the money" by $1.50 or more based on the closing price
of the Company's Common Stock on the date of the resolution.  As a result of the
acceleration,  options to purchase approximately 666,000 shares of the Company's
common stock (which represented  approximately 21% of the Company's  outstanding
stock  options)  became  exercisable  immediately.  The total  number of options
subject to  acceleration  included  options to purchase  575,000  shares held by
executive officers and directors of the Company.  This action was taken to avoid
expense recognition in future financial statements upon adoption of SFAS 123(R).

EMPLOYMENT AGREEMENTS

         Each of Mr. Barry Weiner,  Mr.  Shahram  Rabbani and Dr. Elazar Rabbani
(the "Executives") are parties to an employment agreement effective May 4, 1994,
as  amended  as of July  13,  2000  (the  "Employment  Agreement(s)"),  with the
Company.  Pursuant  to the  terms of  their  respective  Employment  Agreements,
Messrs.  Weiner and Rabbani and Dr.  Rabbani are currently  compensated  for the
calendar year 2005 at a base annual  salary of $410,500,  $410,500 and $447,700,
respectively.  Each Executive  will also receive an annual bonus,  the amount of
which shall be  determined  by the Board of  Directors in its  discretion.  Each
Employment Agreement provides that, in the event of termination of employment by
the Executive for "good  reason," or a termination  of employment by the Company
without "cause" or, additionally, a nonrenewal, as such terms are defined in the
Employment  Agreement,  each Executive shall be entitled to receive:  (a) a lump
sum in an amount equal to three years of the Executive's base annual salary; (b)
a lump sum in an amount  equal to the annual  bonus  paid by the  Company to the
Executive  for the last fiscal year of the Company  ending  prior to the date of
termination  multiplied by three;  (c) insurance  coverage for the Executive and
his  dependents,  at the same level and at the same charges to the  Executive as
immediately prior to his termination,  for a period of three (3) years following
his  termination  from the  Company;  (d) all  accrued  obligations,  as defined
therein;  and (e) with  respect to each  incentive  pay plan  (other  than stock
option or other equity plans) of the Company in which the Executive participated
at the time of  termination,  an amount equal to the amount the Executive  would
have earned if he had continued  employment for three  additional  years. If the
Executive is  terminated  by reason of his  disability,  he shall be entitled to
receive, for three years after such termination, his base annual salary less any
amounts  received  under  a long  term  disability  plan.  If the  Executive  is
terminated by reason of his death, his legal  representatives  shall receive the
balance of any remuneration due him under the terms of his Employment Agreement.
The term of each of the Executive's  Employment  Agreement  currently expires on
May 4, 2006, which term automatically  renews for successive two year periods if
notice to the Company is not given by either party within 180 days of the end of
such successive term.

                                       16


COMPENSATION OF DIRECTORS

         As of  November  1, 2005,  the Lead  Independent  Director  receives an
annual  director's fee of $50,000 and each other person who serves as a director
and  who is not  otherwise  an  officer  or an  employee  (such  director  being
classified  as an  "Outside  Director")  of  the  Company,  receives  an  annual
director's fee of $20,000.  For each meeting of the Board of Directors  attended
in person or by telephone,  the Lead Independent  Director and all other Outside
Directors  receive a fee of $2,000.  Additionally,  each  Outside  Director  who
serves on a  committee  of the Board of  Directors  receives a fee of $1,000 for
each meeting of the committee attended in person or by telephone. In addition to
the $1,000 per  committee  meeting  fee,  the  Chairman  of the Audit  Committee
receives an  additional  fee of $1,000 for each  meeting of the Audit  Committee
attended in person or by telephone,  the Lead Independent  Director  receives an
additional  fee of $500 for each  meeting  of any Board  committee  attended  in
person or by telephone,  and the Chairman of the Compensation  Committee and the
Chairman of the Nominating/Governance  Committee each receives an additional fee
of $500 for each meeting of the  committee  attended in person or by  telephone.
The Lead  Independent  Director  will  receive  10,000  restricted  stock  units
immediately following the Annual Meeting,  provided such person is a director of
the Company at such time. Each of the other Outside Directors will receive 5,000
restricted stock units immediately  following the Annual Meeting,  provided such
person is a director of the Company at such time.  Each of the restricted  stock
units referred to above shall be subject to a two-year vesting period;  provided
that at the  time any  non-employee  director  ceases  to be a  director  of the
Company, such non-employee  director's restricted stock units shall become fully
vested at such time.  The  Company  reimburses  directors  for their  travel and
related expenses in connection with attending meetings of the Board of Directors
and Board-related activities.

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

         The current members of the Compensation  Committee are Messrs.  Gerson,
Delucca and Lazar.  No member of the  Compensation  Committee has a relationship
that would constitute an interlocking  relationship with the Company's executive
officers or other directors.

COMPENSATION COMMITTEE REPORT

         The Company strives to apply a uniform  philosophy to compensation  for
all of its  employees,  including  the  members of its senior  management.  This
philosophy is based on the premise that the  achievements  of the Company result
from the combined and coordinated efforts of all employees working toward common
goals and objectives.

         The  goals  of  the  Company's   compensation   program  are  to  align
remuneration with business objectives and performance, and to enable the Company
to retain and  competitively  reward  executive  officers who  contribute to the
long-term  success  of the  Company.  The  Company's  compensation  program  for
executive officers is based on the following principles, which are applicable to
compensation decisions for all employees of the Company. The Company attempts to
pay its executive officers competitively in order that it will be able to retain
the most capable people in the industry.  Information  with respect to levels of
compensation  being  paid by  comparable  companies  is  obtained  from  various
publications and surveys.

         During the last fiscal year,  the  compensation  of executive  officers
consisted  principally of salary and bonus and the Company granted stock options
to certain of its executive officers,  additional grants of which may be made in
the future.  The cash  portion of such program  includes  base salary and annual
bonuses,  which are awarded in the discretion of the Board of Directors.  Salary
levels  have  been set based  upon  historical  levels,  amounts  being  paid by
comparable companies and performance.  The Company's  equity-based  compensation
consists of the award of  discretionary  stock  options,  which are  designed to
provide  additional  incentives  to executive  officers to maximize  shareholder
value.  Through  the use of  extended  vesting  periods,  the option  program is
designed to encourage executive officers to remain in the employ of the Company.
In addition, because the exercise prices of such options are typically set at or
above  the fair  market  value of the stock on the date the  option is  granted,
executive  officers can only  benefit from such options if the trading  price of
the Company's  shares of Common Stock  increases,  thus aligning their financial
interests directly with those of the shareholders.

         In consideration  for Dr. Elazar Rabbani's  services as Chairman of the
Board of  Directors  and Chief  Executive  Officer of the Company for the fiscal
year ended July 31, 2005, the Company paid Dr. Rabbani an annual

                                       17


salary of $442,200 and a bonus of $283,250.  Such  compensation  was  determined
pursuant to the Company's employment agreement with Dr. Rabbani and was based on
the Board's view of Dr.  Rabbani's  successful  performance  as Chief  Executive
Officer. See "Employment Agreements."

                       Submitted by the members of the Compensation Committee


                       Irwin W. Gerson
                       John J. Delucca
                       Melvin F. Lazar


401(k) PLAN

         The Company has adopted a salary reduction profit sharing plan which is
generally  available  to  employees  of the  Company and any  subsidiary  of the
Company.  Officers and directors who are employees of the Company participate in
the Plan on the same basis as other employees.

         The Plan  permits  voluntary  contributions  by  employees  in  varying
amounts up to 17% of annual earnings (not to exceed the maximum allowable in any
calendar  year which is $14,000 for 2005).  Employee  contributions  are made by
salary  reduction under Section 401(k) of the Internal  Revenue Code of 1986, as
amended (the "Code"), and are excluded from taxable income of the employee.  The
Company  may  also  contribute  additional   discretionary  amounts  as  it  may
determine.

         All employees of the Company who are twenty-one (21) years or older and
have been employed by the Company for a minimum of three (3) months are eligible
to participate in the Plan.  Employees,  who have more than 500 hours of service
per  service  year,  but less than  1,000  hours  per  service  year,  are still
considered  members of the Plan, but  contribution  allocations and vesting will
not increase during such time.

         A  participant's  account  is  distributed  to him upon  retirement  or
termination   of  employment  for  any  reason  and  in  certain  other  limited
situations.  The amount of the Plan  allocation  attributable  to the  Company's
discretionary  contributions  will vest in accordance  with a schedule.  For the
fiscal year ended July 31, 2005,  the Company has made  contributions  of 50% of
the employees'  contribution up to 10% of the employees'  compensation in Common
Stock of the Company.

1999 STOCK OPTION PLAN

         Under the  Company's  1999 Stock  Option  Plan (the "1999  Plan"),  the
Company's  Board of Directors may grant  incentive  stock  options  ("ISOs") and
non-qualified  stock  options  ("NQSOs") to selected key  employees,  directors,
executive  officers,  consultants  and  advisors of the Company to purchase  the
Company's  Common Stock.  ISOs and NQSOs  granted under the 1999 Plan  generally
vest no earlier than six (6) months after the date of grant and can be exercised
no later than the tenth (10th)  anniversary date of the date of grant.  When the
optionee,  however,  holds  more than 10% of all  combined  voting  stock of the
Company,  ISOs granted  under the 1999 Plan cannot be  exercised  later than the
fifth  (5th)  anniversary  date of the date of  grant.  The  exercise  prices of
options  granted  under the 1999 Plan are set by the Board of  Directors  of the
Company, or designated committee.  In any event, however, ISOs granted under the
1999 Plan may not be  exercisable at a price lower than the fair market value of
the Company's  Common Stock on the date such options are granted,  and, when the
optionee  holds more than 10% of all combined  voting stock of the Company,  the
exercise  prices of such  options  may not be less than 110% of the fair  market
value of the  Common  Stock of the  Company on the date of grant.  ISOs  granted
under the 1999 Plan to any optionee which become  exercisable for the first time
in any one  calendar  year for  shares of Common  Stock of the  Company  with an
aggregate  fair market value,  as of the respective  date or dates of grant,  of
more than $100,000 shall be treated as NQSOs. The awards under the 1999 Plan are
subject  to  restrictions  on   transferability,   are  forfeitable  in  certain
circumstances  and are  exercisable at such time or times and during such period
as shall be set forth in the option agreement evidencing such option. During the
fiscal year ended July 31, 2005, options to purchase up to 399,975 shares of the
Company's Common Stock were awarded under the 1999 Plan. As of the

                                       18


Record Date, of the 2,187,224  shares of the Company's Common Stock reserved for
issuance upon the exercise of options  authorized for grant under the 1999 Plan,
62,305 shares of the Company's  Common Stock remain  available for issuance upon
the exercise of options authorized for grant under the 1999 Plan.

2005 EQUITY COMPENSATION INCENTIVE PLAN

         On October 5,  2004,  our Board of  Directors  approved  the  adoption,
subject  to  approval  by  our  shareholders,   of  the  Company's  2005  Equity
Compensation  Incentive  Plan for the purpose of  recruiting  and  retaining our
officers, employees,  directors,  consultants and advisors pursuant to the terms
of a program to be administered by our  Compensation  Committee.  On January 20,
2005, at the 2005 Annual Meeting of Shareholders,  our shareholders approved the
2005 Equity  Compensation  Incentive  Plan.  On October 31, 2005,  the Company's
Board of Directors  amended the 2005 Equity  Compensation  Incentive  Plan among
other  things to (a) permit  restricted  stock unit  awards to be made,  (b) add
specific  performance  criteria  that  may  be  used  to  establish  performance
objectives,  the  achievement  of which will allow certain  awards to vest or be
issued,  which in turn will allow the Company to receive  income tax  deductions
under  Section  162(m) of the Code,  and (c) eliminate  automatic  annual option
grants to the Company's non-employee directors. Our Shareholders are being asked
to ratify and approve such  amendments  in Proposal 2. Please see  "Proposal 2 -
Amendment and  Restatement of the Company's 2005 Equity  Incentive  Compensation
Plan" for a detailed description of the amended and restated plan.

         As of the Record Date, 32,000 shares of the Company's Common Stock have
been reserved for issuance  upon the exercise of options  granted under the 2005
Equity  Compensation  Incentive  Plan. In addition,  as of the Record Date,  the
Board of  Directors  has  approved  the award  under the 2005 Plan of (a) 10,000
restricted stock units to the Lead Independent  Director  immediately  following
the  Annual  Meeting,  (b)  5,000  restricted  stock  units to each of the other
Outside Directors immediately following the Annual Meeting, and (c) 7,500 shares
of restricted stock to each of two employees of the Company.

INSURANCE FOR INDEMNIFICATION OF DIRECTORS AND OFFICERS

         The Company has in effect, with Darwin Professional Underwriters,  Inc.
and XL Specialty  Insurance Company under a policy effective  February 21, 2005,
and expiring on February 22, 2006,  insurance  covering all of its directors and
officers and certain other employees of the Company against certain  liabilities
and reimbursing  the Company for obligations  which it incurs as a result of its
indemnification  of such directors,  officers and employees.  Such insurance has
been obtained in accordance  with the  provisions of Section 726 of the Business
Corporation Law of the State of New York. The annual premium is $280,000.

         This report has been provided by the Board of Directors of the Company.

                           Elazar Rabbani, Ph.D.
                           Shahram K. Rabbani
                           Barry W. Weiner
                           Marcus A. Conant M.D.
                           John J. Delucca
                           Irwin C. Gerson
                           Melvin F. Lazar, CPA
                           John B. Sias

                                       19


PERFORMANCE GRAPH

         The graph below  compares the five-year  cumulative  shareholder  total
return based upon an initial  $100  investment  (assuming  the  reinvestment  of
dividends)  for Enzo Biochem,  Inc.  shares of Common Stock with the  comparable
return for the New York Stock  Exchange  Market  Value Index and two peer issuer
indices selected on an industry basis.  The two peer group indices include:  (i)
60 biotechnology companies engaged in the research and development of diagnostic
substances and (ii) 10 companies engaged in the medical  laboratories  business.
All of the indices include only companies whose common stock has been registered
under  Section 12 of the  Securities  Exchange Act of 1934 for at least the time
frame set forth in the graph.

         The total shareholder returns depicted in the graph are not necessarily
indicative of future  performance.  The Performance Graph and related disclosure
shall not be deemed to be incorporated by reference in any filing by the Company
under the Securities Act of 1933 or the Securities  Exchange Act of 1934, except
to the extent  that the  Company  specifically  incorporates  the graph and such
disclosure by reference.


                               [GRAPHIC OMITTED]


              COMPARISON OF CUMULATIVE TOTAL RETURN OF ONE OR MORE
          COMPANIES, PEER GROUPS, INDUSTRY INDEXES AND/OR BROAD MARKETS

                          2000      2001    2002     2003      2004     2005
                          ----      ----    ----     ----      ----     ----
 ENZO BIOCHEM, INC.      100.00    49.59    27.38    42.90    28.23     36.48
MEDICAL LABORATORIES     100.00   108.09    75.86    80.64    88.65    113.47
  NYSE MARKET INDEX      100.00    97.62    79.02    86.70    99.41    117.57
 BIOTECHNOLOGY PEETS     100.00    83.04    69.71    83.48    93.03    105.72

                                       20


                                   PROPOSAL 2
             AMENDMENT AND RESTATEMENT OF THE COMPANY'S 2005 EQUITY
                          COMPENSATION INCENTIVE PLAN

         On October 5, 2004, our Board of Directors adopted, subject to approval
by our shareholders,  the Company's 2005 Equity Compensation Incentive Plan (the
"2005  Plan")  for  the  purpose  of  recruiting  and  retaining  our  officers,
employees, directors, consultants and advisors. On January 20, 2005, at the 2005
Annual Meeting of Shareholders, our shareholders approved the 2005 Plan.

         The Board of Directors  believes that the  fundamental  objectives of a
long-term  incentive   compensation  program  are  to  align  the  interests  of
management and the shareholders and to create long-term  shareholder  value. The
Board of Directors  believes that the 2005 Plan increases the Company's  ability
to achieve these objectives by allowing for stock option and other stock awards,
which will help the  Company  recruit,  reward,  motivate  and  retain  talented
personnel.  Changes in the  equity  compensation  accounting  rules also make it
important  for us to have greater  flexibility  under the 2005 Plan.  As the new
equity  compensation  accounting  rules  come into  effect,  competitive  equity
compensation practices may change materially,  especially as they pertain to the
use of equity  compensation  vehicles  other than stock options.  Moreover,  the
Board of Directors believes that it is in the Company's best interests to enable
the Compensation  Committee to maintain  discretion over the nature,  timing and
amount of awards to be  granted  to all  eligible  persons  under the 2005 Plan,
including  non-employee  directors.   Accordingly,  on  October  31,  2005,  the
Company's  Board of  Directors  amended the 2005 Plan among other  things to (a)
permit  restricted  stock unit awards to be made,  (b) add specific  performance
criteria that may be used to establish performance  objectives,  the achievement
of which will  allow  certain  awards to vest or be  issued,  which in turn will
enable the Company to claim income tax deductions with regard to the limitations
under Section  162(m) of the Code (see "Summary of the Amended 2005  Plan--Stock
Awards and Performance  Based  Compensation"  and "Federal Income Tax Aspects of
the  Amended  2005  Plan--Section  162(m) of the  Code"  below),  (c)  eliminate
automatic annual option grants to the Company's  non-employee  directors and (d)
make certain other related changes to the 2005 Plan.

         Because the amendment to add specific  performance criteria for Section
162(m) purposes requires shareholder ratification and approval, our shareholders
are being asked to ratify and approve the amendment and  restatement of the 2005
Plan (as amended and restated,  the "Amended 2005 Plan") at the Annual  Meeting.
Ratification and approval of the Amended 2005 Plan requires the affirmative vote
of a majority  of the votes  cast on the  matter by  holders of our  outstanding
shares of common stock at the Annual Meeting,  provided a quorum is present.  If
shareholders  ratify and approve the Amended 2005 Plan, it will replace the 2005
Plan. If  shareholders do not ratify and approve the Amended 2005 Plan, only the
amendments  to the 2005 Plan to permit  restricted  stock unit awards to be made
and to eliminate  automatic  annual option grants to the Company's  non-employee
directors will be effective.  Our named executive officers and directors have an
interest in this proposal.

         A general  description of the principal  terms of the Amended 2005 Plan
and the purpose of the amendment and  restatement  of the 2005 Plan is set forth
below. Unless otherwise marked, all properly signed and returned proxies will be
voted FOR Proposal No. 2.

CHANGES BEING MADE TO THE 2005 PLAN

         The following is a summary of the changes being made to the 2005 Plan:

         o   The 2005 Plan  currently  allows for the grant of stock options and
             awards of  restricted  stock.  In  addition  to those  awards,  the
             Amended 2005 Plan would permit the award of restricted  stock units
             and dividend equivalents.  Awards of shares of restricted stock and
             restricted stock units are commonly known as "full value awards."

         o   The 2005 Plan has also been  amended  to add  specific  performance
             criteria  that  the  Compensation  Committee  may use to  establish
             performance objectives,  the achievement of which may be conditions
             for certain awards to vest or be issued,  which in turn will enable
             the Company to claim income tax

                                       21


             deductions  for  those  awards  without  regard  to  the  deduction
             limitations under Section 162(m) of the Code.

         o   The 2005 Plan is also being  amended  to  eliminate  the  automatic
             annual option  grants to Outside  Directors.  The automatic  annual
             grant provisions  provided that on the date an Outside Director was
             first  elected to serve on the Company's  Board of Directors,  such
             Outside Director would receive options to purchase 15,000 shares of
             the Company's Common Stock and would automatically  receive options
             to purchase 12,500 shares of the Company's Common Stock immediately
             following  the  date  of  each  annual  meeting  of  the  Company's
             shareholders.  Under  the  terms  of the  Amended  2005  Plan,  the
             Compensation  Committee  will  determine,  in its  discretion,  the
             timing and amount of awards to be  granted to both  management  and
             non-management Directors of the Company.

         The  Amended  2005 Plan does not differ from the 2005 Plan in any other
material respect.

         The Company believes strongly that the ratification and approval of the
Amended 2005 Plan is essential to the Company's continued success. The Company's
employees are its most valuable  assets.  Stock options and other awards such as
those provided under the Amended 2005 Plan are vital to the Company's ability to
attract and retain  outstanding and highly skilled  individuals in the extremely
competitive  labor markets in which the Company must  compete.  Such awards also
are crucial to our ability to motivate employees to achieve the Company's goals.
For the reasons  stated above,  the  shareholders  are being asked to ratify and
approve the Amended 2005 Plan at the Annual Meeting.

SUMMARY OF THE AMENDED 2005 PLAN

         The following paragraphs provide a summary of the principal features of
the Amended 2005 Plan and its operation.  The following  summary is qualified in
its  entirety  by  reference  to the  Amended  2005 Plan as set forth in Annex A
attached to this proxy statement. Capitalized terms not otherwise defined herein
shall have the meaning ascribed to them in the Amended 2005 Plan.

         ADMINISTRATION

         Administration  of  the  Amended  2005  Plan  is  carried  out  by  the
Compensation Committee of the Board of Directors. The Compensation Committee may
delegate a portion of its  authority  under the Amended 2005 Plan to one or more
of our officers.  As used in this summary,  the term  "administrator"  means the
Compensation Committee or its delegate.

         ELIGIBILITY

         Our officers and employees and those of our  subsidiaries  are eligible
to  participate  in the Amended 2005 Plan.  Our directors and other persons that
provide  consulting  or advisory  services to us and our  subsidiaries  are also
eligible to participate in the Amended 2005 Plan. The term subsidiary is used in
this  summary to refer to both  corporate  subsidiaries  and other  entities for
which we directly or indirectly control at least 50% of the equity.

         MAXIMUM SHARES AND AWARD LIMITS

         Under the Amended  2005 Plan,  the  maximum  number of shares of common
stock  that may be  subject  to  stock  options,  restricted  stock  awards  and
restricted stock unit awards is 1,000,000. No one participant may receive awards
representing  more than 200,000 shares of common stock in any one calendar year.
These limitations, and the terms of outstanding awards, will be adjusted without
the approval of our shareholders as the administrator  determines is appropriate
in the event of a stock  dividend,  stock  split,  reclassification  of stock or
similar events. If an option terminates,  expires or becomes  unexercisable,  or
shares of common stock subject to a restricted  stock award or restricted  stock
unit award are forfeited,  the shares subject to such option,  restricted  stock
award or restricted  stock unit award are available  under the first sentence of
this  paragraph  for future  awards  under the Amended  2005 Plan.  In addition,
shares which are issued under any type of award under the Amended 2005 Plan

                                       22


and which are repurchased or reacquired by us at the original purchase price for
such shares are also  available  under the first  sentence of this paragraph for
future awards under the Amended 2005 Plan.

         STOCK OPTIONS

         The Amended 2005 Plan  provides for the grant of both options  intended
to qualify as incentive  stock options under Section 422 of the Code and options
that are not  intended to so qualify.  Options  intended to qualify as incentive
stock  options  may be granted  only to  persons  who are our  employees  or are
employees  of our  subsidiaries  which are treated as  corporations  for federal
income tax purposes.  No participant may be granted incentive stock options that
are  exercisable for the first time in any calendar year for common stock having
a total fair  market  value  (determined  as of the  option  grant) in excess of
$100,000.

         The administrator  will select the participants who are granted options
and,  consistent  with the terms of the Amended 2005 Plan,  will  prescribe  the
terms of each option,  including the vesting  rules for such option.  The option
exercise  price cannot be less than the common  stock's fair market value on the
date the option is granted, and in the event a participant is deemed to be a 10%
owner  of our  Company  or one of our  subsidiaries,  the  exercise  price of an
incentive  stock  option  cannot be less than 110% of the  common  stock's  fair
market value on the date the option is granted.  The Amended 2005 Plan prohibits
repricing of an outstanding  option,  and therefore,  the administrator may not,
without  the  consent  of the  shareholders,  lower  the  exercise  price  of an
outstanding  option.  This limitation  does not,  however,  prevent  adjustments
resulting  from stock  dividends,  stock splits,  reclassifications  of stock or
similar events. The option price may be paid in cash, by surrendering  shares of
common  stock,  or a  combination  of cash  and  shares  of  common  stock,  the
withholding of shares, or by using a "cashless  exercise" feature.  Such methods
of paying the exercise  price shall be  determined by the  administrator  in its
sole discretion. Options may be exercised in accordance with requirements set by
the  administrator.  The maximum period in which an option may be exercised will
be fixed by the  administrator  but cannot exceed ten years,  and in the event a
participant  is deemed to be a 10% owner of our Company or one of our  corporate
subsidiaries,  the maximum period for an incentive  stock option granted to such
participant cannot exceed five years.  Options generally will be nontransferable
except in the event of the  participant's  death but the administrator may allow
the transfer of non-qualified stock options through a gift or domestic relations
order to the participant's family members.

         Unless provided otherwise in a participant's stock option agreement and
subject to the maximum exercise period for the option,  an option generally will
cease  to be  exercisable  upon  the  earlier  of  three  months  following  the
participant's  termination of service with us or the  expiration  date under the
terms of the  participant's  stock  option  agreement.  The right to exercise an
option  will expire  immediately  upon  termination  if the  termination  is for
"cause" or a voluntary termination any time after an event that would be grounds
for termination for cause. Upon death or disability,  the option exercise period
is  extended to the earlier of one year from the  participant's  termination  of
service or the expiration date under the terms of the participant's stock option
agreement.

         STOCK AWARDS AND PERFORMANCE BASED COMPENSATION

         The  administrator  also will select the  participants  who are granted
restricted stock awards and/or restricted stock unit awards and, consistent with
the terms of the Amended 2005 Plan,  will establish the terms of each restricted
stock award and  restricted  stock unit award.  Awards of  restricted  stock are
rights to acquire or purchase shares of the Company's Common Stock. A restricted
stock award may be subject to payment by the participant of a purchase price for
shares of common  stock  subject  to the  award,  and may be  subject to vesting
requirements   or  transfer   restrictions  or  both,  if  so  provided  by  the
administrator.  Those requirements may include,  for example, a requirement that
the  participant  complete  a  specified  period  of  service  or  that  certain
performance objectives be achieved.  Awards of restricted stock units are dollar
value  equivalents  of  shares  that  vest in  accordance  with  the  terms  and
conditions  established  by the  administrator  in its  sole  discretion.  Those
requirements  may  include,  for example,  a  requirement  that the  participant
complete a specified period of service or that certain performance objectives be
achieved.  Upon  satisfying the applicable  vesting  criteria,  a participant is
entitled to the payout in accordance  with,  and at the times  specified in, the
award  agreement.  The  administrator  may pay earned  restricted stock units in
cash, shares or a combination of both.

         As determined by the administrator,  the performance  objectives may be
based on the individual  performance of the participant,  our performance or the
performance of our subsidiaries, divisions, departments or

                                       23


functions in which the  participant  is employed or has  responsibility.  In the
case of a performance objective for an award intended to qualify as "performance
based  compensation"  under  Section  162(m)  of the  Code,  one or  more of the
following business criteria for the Company,  on a consolidated  basis, and/or a
Subsidiary,  or for  business  or  geographical  units of the  Company  and/or a
Subsidiary (except with respect to the total shareholder return and earnings per
share criteria),  shall be used by the administrator in establishing performance
objectives for such awards: (1) earnings per share; (2) revenues or margins; (3)
cash flow; (4) operating margin; (5) return on net assets, investment,  capital,
or equity;  (6) economic value added; (7) direct  contribution;  (8) net income;
pretax earnings;  earnings before interest and taxes;  earnings before interest,
taxes, depreciation and amortization; earnings after interest expense and before
extraordinary or special items;  operating income; income before interest income
or  expense,  unusual  items and  income  taxes,  local,  state or  federal  and
excluding  budgeted  and actual  bonuses  which  might be paid under any ongoing
bonus plans of the Company; (9) working capital;  (10) management of fixed costs
or  variable   costs;   (11)   identification   or  consummation  of  investment
opportunities  or completion of specified  projects in accordance with corporate
business plans, including strategic mergers, acquisitions or divestitures;  (12)
total shareholder return; and (13) debt reduction. Any of the above goals may be
determined on an absolute or relative basis or as compared to the performance of
a published or special index deemed applicable by the  administrator  including,
but not  limited  to,  the  Standard  &  Poor's  500  Stock  Index or a group of
companies that are comparable to the Company.  The  administrator  shall exclude
the impact of an event or occurrence which the  administrator  determines should
appropriately  be excluded,  including  without  limitation (i)  restructurings,
discontinued operations, extraordinary items, and other unusual or non-recurring
charges,  (ii) an event either not  directly  related to the  operations  of the
Company or not within the  reasonable  control of the Company's  management,  or
(iii) a change in accounting standards required by generally accepted accounting
principles.  Transfer  of the shares of common  stock  subject to a stock  award
normally will be restricted prior to vesting.

         AMENDMENT AND TERMINATION

         No awards may be granted  under the  Amended  2005 Plan after the tenth
anniversary of the adoption of the Amended 2005 Plan. The Board of Directors may
amend or terminate the Amended 2005 Plan at any time,  but an amendment will not
become  effective  without the approval of our  shareholders if it increases the
aggregate  number of shares of common stock that may be issued under the Amended
2005 Plan,  changes the class of employees  eligible to receive  incentive stock
options or shareholder approval is required by any applicable law, regulation or
rule, including any rule of the NYSE. No amendment or termination of the Amended
2005 Plan will affect a participant's  rights under  outstanding  awards without
the participant's consent.

AWARDS GRANTED TO EMPLOYEES, CONSULTANTS AND DIRECTORS

         No awards have been granted  under the 2005 Plan during the fiscal year
ended  July 31,  2005.  As of the date of this  proxy  statement,  no  executive
officer,  employee or director,  and no associate  of any  executive  officer or
director,  has  been  granted  any  options  or full  value  awards  subject  to
shareholder  approval of the proposed Amended 2005 Plan. All future awards to be
received by the Company's  directors,  executive officers and employees pursuant
to the Amended 2005 Plan will be in the  discretion  of the  administrator  and,
therefore,  are not  determinable at this time;  however,  to date, the Board of
Directors  has approved  the award under the 2005 Plan of (a) 10,000  restricted
stock units to the Lead Independent  Director  immediately  following the Annual
Meeting, (b) 5,000 restricted stock units to each of the other Outside Directors
immediately  following the Annual Meeting,  (c) 7,500 shares of restricted stock
to each  of two  employees  of the  Company,  and (d)  options  to  purchase  an
aggregate amount of 32,000 shares of the Company's Common Stock to employees and
consultants  of the Company.  The  following  table sets forth (a) the aggregate
number of shares of restricted stock or restricted stock units granted under the
2005 Plan as of the record date for the Annual  Meeting and (b) the dollar value
thereof.

                                       24




----------------------------------------------------------------------------------------------------------------
                                       NUMBER OF OPTIONS ("OS"), SHARES OF        DOLLAR VALUE OF OPTIONS,
NAME OF INDIVIDUAL OR GROUP                  RESTRICTED STOCK ("RS")                  RESTRICTED STOCK
                                        OR RESTRICTED STOCK UNITS ("RSUS")       OR RESTRICTED STOCK UNITS
----------------------------------------------------------------------------------------------------------------
                                                                                       
Elazar Rabbani, Ph.D.                                   0                                    $0
----------------------------------------------------------------------------------------------------------------

Shahram Rabbani                                         0                                    $0
----------------------------------------------------------------------------------------------------------------

Barry W. Weiner                                         0                                    $0
----------------------------------------------------------------------------------------------------------------

Dean Engelhardt, Ph.D.                                  0                                    $0
----------------------------------------------------------------------------------------------------------------

Norman E. Kelker, Ph.D.                                 0                                    $0
----------------------------------------------------------------------------------------------------------------

All executive officers, as a group                      0                                    $0
----------------------------------------------------------------------------------------------------------------

All directors who are not                         30,000 (RSUs)                            $* (RSUs)
executive officers, as a group
----------------------------------------------------------------------------------------------------------------

All employees who are not                           22,000 (Os)                          $265,540 (Os)
executive officers, as a group                      15,000 (RS)                          $196,950 (RS)
----------------------------------------------------------------------------------------------------------------


* These RSUs will be issued  subsequent  to the January 19, 2006 Annual  Meeting
and therefore have no value as of the date hereof.  Upon issuance such RSUs will
be valued at the closing  price on January 19, 2006  multiplied by the number of
RSUs granted.

FEDERAL INCOME TAX ASPECTS OF THE AMENDED 2005 PLAN

         The following is a brief  summary of the federal  income tax aspects of
awards that may be made under the Amended 2005 Plan based on U.S. federal income
tax laws in effect on the date of this proxy  statement.  This summary  provides
only the basic tax rules.  It does not  describe a number of special  tax rules,
including  the  alternative  minimum  tax  and  various  elections  that  may be
applicable under certain circumstances. The tax consequences of awards under the
Amended  2005  Plan  depend  upon the type of  award  and if the  award is to an
executive officer, whether the award qualifies as performance-based compensation
under  Section  162(m) of the Code.  In  addition,  administrative  and judicial
interpretations  of the  application  of the U.S.  federal  income  tax laws are
subject to change. Furthermore, no information is given with respect to state or
local taxes that may be applicable to any awards.

         The recipient of an incentive stock option  generally will not be taxed
upon grant of the option.  Federal income taxes are generally  imposed only when
the shares of stock from exercised  incentive  stock options are disposed of, by
sale or otherwise. The amount by which the fair market value of the stock on the
date of exercise exceeds the exercise price is, however, included in determining
the  option  recipient's  liability  for the  alternative  minimum  tax.  If the
incentive  stock  option  recipient  does not sell or dispose of the stock until
more than one year after the receipt of the stock and two years after the option
was granted, then, upon sale or disposition of the stock, the difference between
the exercise  price and the market value of the stock as of the date of exercise
will be treated as a capital gain, and not ordinary income. If a recipient fails
to hold the stock for the minimum  required time, at the time of the disposition
of the  stock,  the  recipient  will  recognize  ordinary  income in the year of
disposition  in an amount  equal to any excess of the market value of the common
stock on the date of exercise (or, if less,  the amount  realized on disposition
of the shares) over the exercise price paid for the shares. Any further gain (or
loss)  realized  by the  recipient  generally  will be  taxed as  short-term  or
long-term gain (or loss) depending on the holding  period.  The Company will not
receive  a tax  deduction  for  incentive  stock  options  which  are taxed to a
recipient as capital gains; however, the Company will receive a tax deduction if
the sale of the stock does not qualify for capital gains tax treatment.

         NONQUALIFIED STOCK OPTIONS

         The  recipient  of stock  options not  qualifying  as  incentive  stock
options generally will not be taxed upon the grant of the option. Federal income
taxes are generally due from a recipient of nonqualified  stock options when the
stock options are exercised.  The  difference  between the exercise price of the
option and the fair market value of the stock purchased on such date is taxed as
ordinary income (and subject to withholding and employment taxes when the option
is exercised).  Thereafter, the tax basis for the acquired stock is equal to the
amount paid for the stock plus the amount of ordinary  income  recognized by the
recipient. The Company will take a tax deduction equal to the amount of ordinary
income realized by the option recipient by reason of the exercise of the option.

                                       25


         STOCK AWARDS

         The payment of stock awards under the Amended 2005 Plan will  generally
be treated as  ordinary  compensation  income at the time of payment  or, in the
case of restricted  common stock subject to a vesting  requirement,  at the time
substantial vesting occurs. A recipient who receives restricted shares which are
not  substantially  vested,  may,  within  30 days of the  date the  shares  are
transferred,  elect in  accordance  with Section  83(b) of the Code to recognize
ordinary  compensation  income at the time of transfer of the shares. The amount
of  ordinary  compensation  income  is equal to the  amount  of any cash and the
amount by which the then fair market value of any common  stock  received by the
participant exceeds the purchase price, if any, paid by the participant. Subject
to the application of Section 162(m) of the Code, the Company will receive a tax
deduction for the amount of the compensation income.

         SECTION 162(m) OF THE CODE

         Section 162(m) of the Code would render  non-deductible  to the Company
certain  compensation in excess of $1,000,000 in any year to certain officers of
the Company unless such excess is  "performance-based  compensation" (as defined
in the Code) or is otherwise  exempt from Section  162(m).  Awards granted under
the Amended  2005 Plan are  designed to be able to qualify as  performance-based
compensation.  As  described  above with respect to  restricted  stock awards or
restricted  stock unit awards,  the  administrator  may condition such awards on
attainment  of one or more  performance  goals that are intended to qualify such
awards as performance-based compensation.

         THE BOARD OF DIRECTORS  RECOMMENDS A VOTE "FOR"  PROPOSAL 2 RELATING TO
THE RATIFICATION AND APPROVAL OF THE AMENDED 2005 PLAN. PROXIES SOLICITED BY THE
BOARD OF DIRECTORS WILL BE SO VOTED UNLESS SHAREHOLDERS SPECIFY IN THEIR PROXIES
A CONTRARY CHOICE.

                                       26


                                   PROPOSAL 3
            APPROVAL OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

         The  Board  of  Directors  has  appointed  Ernst  & Young  LLP,  as its
independent  registered  public  accounting  firm,  to audit the accounts of the
Company  for the  fiscal  year  ending  July 31,  2005.  The Board of  Directors
approved the  reappointment  of Ernst & Young LLP (which has been engaged as the
Company's  independent  registered public  accounting firm since 1983).  Ernst &
Young LLP has advised the Company  that  neither the firm nor any of its members
or  associates  has any direct  financial  interest in the Company or any of its
affiliates  other than as auditors.  Although the selection and  appointment  of
independent  auditors is not required to be submitted to a vote of shareholders,
the Directors  deem it desirable to obtain the  shareholders'  ratification  and
approval of this appointment.

         The  following  table sets forth the  aggregate  fees billed by Ernst &
Young LLP for the years  ended  July 31,  2005 and 2004 for audit and  non-audit
services (as well as all "out-of-pocket" costs incurred in connection with these
services) and are  categorized as Audit Fees,  Audit-Related  Fees, Tax Fees and
All Other Fees.  The nature of the  services  provided in each such  category is
described following the table.

                ---------------------------------------------------------------
                                                     2005               2004
                ---------------------------------------------------------------
                AUDIT FEES                         $667,500           $215,000
                ---------------------------------------------------------------
                AUDIT-RELATED FEES                        0             16,000
                ---------------------------------------------------------------
                TAX FEES                                  0              8,000
                ---------------------------------------------------------------
                ALL OTHER FEES                            0                  0
                ---------------------------------------------------------------

                ---------------------------------------------------------------
                TOTAL FEES                         $667,500           $239,000
                                                   --------           --------
                ---------------------------------------------------------------

         AUDIT FEES - Consists of professional  services  rendered in connection
with the annual audit of the Company's consolidated financial statements on Form
10-K and quarterly reviews of the Company's interim financial statements on Form
10-Q.  Audit fees also include fees for services  performed by Ernst & Young LLP
that are  closely  related to the audit and in many cases could only be provided
by the Company's  independent  auditors.  Such services  include the issuance of
comfort letters and consents  related to the Company's  registration  statements
and capital  raising  activities,  assistance with and review of other documents
filed with the Commission and accounting advice on completed transactions.

         AUDIT  RELATED  FEES -  Consists  of  services  related  to  audits  of
properties  acquired,  due diligence  services related to contemplated  property
acquisitions and accounting consultations.  The 2005 and 2004 fees were incurred
in connection with consultations  regarding the Company's  implementation of The
Sarbanes-Oxley Act of 2002.

         TAX FEES - Consists of services  related to corporate  tax  compliance,
including  review of corporate  tax returns,  review of the tax  treatments  for
certain expenses and tax due diligence relating to acquisitions.

         ALL OTHER FEES - There were no professional  services rendered by Ernst
& Young LLP that would be  classified  as other fees during the years ended July
31, 2005 and 2004.

         Pre-Approval  Policies and Procedures - The Audit Committee has adopted
a policy  that  requires  advance  approval  of all  audit,  audit-related,  tax
services,  and other services performed by the independent  auditor.  The policy
provides for  pre-approval by the Audit Committee of specifically  defined audit
and  non-audit  services.  Unless  the  specific  service  has  been  previously
pre-approved  with respect to that year,  the Audit  Committee  must approve the
permitted  service before the independent  auditor is engaged to perform it. The
Audit Committee has delegated to the Chair of the Audit  Committee  authority to
approve permitted  services provided that the Chair reports any decisions to the
Committee at its next scheduled meeting.

         In making  its  recommendations  to ratify the  appointment  of Ernst &
Young LLP as the Company's  independent  accountants  for the fiscal year ending
July 31, 2005, the Audit Committee has considered whether the non-audit services
provided by Ernst & Young LLP are compatible with  maintaining the  independence
of Ernst & Young LLP.

                                       27


         Representatives  of Ernst & Young LLP are expected to be present at the
Annual Meeting with the  opportunity to make a statement if they desire to do so
and are expected to be available to respond to appropriate questions.

         THE BOARD OF DIRECTORS  RECOMMENDS A VOTE "FOR"  PROPOSAL 3 RELATING TO
THE  RATIFICATION OF THE APPOINTMENT OF THE AUDITORS.  PROXIES  SOLICITED BY THE
BOARD OF DIRECTORS WILL BE SO VOTED UNLESS SHAREHOLDERS SPECIFY IN THEIR PROXIES
A CONTRARY CHOICE.

                                       28


                                     GENERAL

         The  Management  of the Company does not know of any matters other than
those stated in this Proxy Statement which are to be presented for action at the
meeting.  If any other matters  should  properly come before the meeting,  it is
intended that proxies in the accompanying form will be voted on any such matters
in   accordance   with  the  judgment  of  the  persons   voting  such  proxies.
Discretionary  authority  to vote on such  matters is  conferred by such proxies
upon the persons voting them.

         The Company will bear the cost of preparing, assembling and mailing the
Proxy,  Proxy Statement and other material which may be sent to the shareholders
in connection with this solicitation. In addition to the solicitation of proxies
by use of the mails,  officers and regular  employees  may solicit the return of
proxies.  The Company may reimburse  persons  holding stock in their names or in
the names of other  nominees  for their  expense  in sending  proxies  and proxy
material to  principals.  In addition,  American Stock Transfer & Trust Company,
6201 15th Avenue,  Brooklyn,  NY 11219,  the Company's  transfer agent, has been
engaged  to  solicit  proxies  on behalf  of the  Company  for a fee,  excluding
expenses,  of approximately  $5,000.  Proxies may be solicited by mail, personal
interview, telephone and telegraph.

         ENZO WEBSITE

         In addition to the information  about the Company and its  subsidiaries
contained in this proxy statement,  extensive  information about the Company can
be found on our website located at www.enzo.com, including information about our
management team, products and services and our corporate governance practices.

         The  corporate  governance  information  on our  website  includes  the
Company's Corporate Governance Guidelines,  the Code of Conduct and the charters
of each of the  committees  of the Board of  Directors.  These  documents can be
accessed  at  www.enzo.com.   Printed  versions  of  our  Corporate   Governance
Guidelines, our Code of Conduct and the charters for our Board committees can be
obtained,  free of charge, by writing to the Company at: Enzo Biochem,  Inc., 60
Executive Boulevard, Farmingdale, New York 11735, Attn: Corporate Secretary.

         This  information  about Enzo's website and its content,  together with
other references to the website made in this proxy statement, is for information
only and the content of the Company's  website is not deemed to be  incorporated
by reference in this proxy  statement or otherwise filed with the Securities and
Exchange Commission.

         THE COMPANY WILL PROVIDE  WITHOUT CHARGE TO EACH PERSON BEING SOLICITED
BY THIS PROXY STATEMENT,  UPON THE WRITTEN REQUEST OF ANY SUCH PERSON, A COPY OF
THE ANNUAL  REPORT OF THE  COMPANY ON FORM 10-K FOR THE YEAR ENDED JULY 31, 2005
(AS FILED WITH THE SECURITIES AND EXCHANGE  COMMISSION)  INCLUDING THE FINANCIAL
STATEMENTS AND THE SCHEDULES  THERETO.  ALL SUCH REQUESTS  SHOULD BE DIRECTED TO
SHAHRAM K.  RABBANI,  SECRETARY,  ENZO BIOCHEM,  INC.,  60 EXECUTIVE  BOULEVARD,
FARMINGDALE, NEW YORK 11735.


                      SHAREHOLDER PROPOSALS TO BE PRESENTED
                           AT THE NEXT ANNUAL MEETING

         Shareholder  Proposals.   Proposals  of  shareholders  intended  to  be
presented at the Company's 2006 Annual Shareholder  Meeting (i) must be received
by the Company at its  offices no later than July 31,  2006 (120 days  preceding
the one year anniversary of the Mailing Date), (ii) may not exceed 500 words and
(iii) must otherwise  satisfy the  conditions  established by the Securities and
Exchange  Commission for  shareholder  proposals to be included in the Company's
Proxy Statement and form of proxy for that meeting.

         Discretionary  Proposals.  Shareholders intending to commence their own
proxy  solicitations  and  present  proposals  from the floor of the 2006 Annual
Shareholder Meeting in compliance with Rule 14a-4 promulgated under the Exchange
Act of 1934,  as  amended,  must notify the  Company of such  intentions  before
October  12, 2006 (45 days  preceding  the one year  anniversary  of the Mailing
Date).  After such date, the Company's  proxy in connection with the 2006 Annual
Shareholder Meeting may confer discretionary authority on the Board to vote.

                                       29


                                             By Order of the Board of Directors


                                             Shahram K. Rabbani, SECRETARY


DATED: NOVEMBER 28, 2005

                                       30


                                                                         ANNEX A


                               ENZO BIOCHEM, INC.
                     2005 EQUITY COMPENSATION INCENTIVE PLAN

  as Amended and Restated by the Board of Directors, effective October 31, 2005

1.       PURPOSE

         The Enzo Biochem, Inc. 2005 Equity Compensation Incentive Plan is
intended to promote the best interests of Enzo Biochem, Inc. (the "Company") and
its shareholders by (i) assisting the Company and its Subsidiaries in the
recruitment and retention of persons with ability and initiative, (ii) providing
an incentive to such persons to contribute to the growth and success of the
businesses of the Company and its Subsidiaries by affording such persons equity
participation in the Company and (iii) associating the interests of such persons
with those of the Company and its Subsidiaries and shareholders.

2.       DEFINITIONS

         As used in the Plan the following definitions shall apply:

         "AWARD" means any Option, Restricted Stock Award or Restricted Stock
Unit Award granted hereunder.

         "BOARD" means the Board of Directors of the Company.

         "CAUSE" means in the case where the Participant does not have an
employment, consulting or similar agreement in effect with the Company or its
Subsidiaries or where there is such an agreement but it does not define "cause"
(or words of like import), conduct related to the Participant's service to the
Company or a Subsidiary for which either criminal or civil penalties against the
Participant may be sought, misconduct, insubordination, material violation of
the Company's or its Subsidiaries policies, disclosing or misusing any
confidential information or material concerning the Company or any Subsidiary or
material breach of any employment, consulting agreement, non-competition,
non-solicitation or confidentiality agreement or similar agreement, or in the
case where the Participant has an employment agreement, consulting agreement or
similar agreement that defines a termination for "cause" (or words of like
import), "cause" as defined in such agreement; provided, however, that with
regard to any agreement that defines "cause" on occurrence of or in connection
with change of control, such definition of "cause" shall not apply until a
change of control actually occurs and then only with regard to a termination
thereafter.

         "CODE" means the Internal Revenue Code of 1986, and any amendments
thereto.

         "COMMITTEE" means the Compensation Committee of the Board acting as
administrator of the Plan pursuant to Section 3 hereof. The Committee shall
consist solely of three (3) or more Directors who are (i) Non-Employee Directors
(within the meaning of Rule 16b-3 under the Exchange Act) for purposes of
exercising administrative authority with respect to Awards granted to Eligible
Persons who are subject to Section 16 of the Exchange Act; (ii) to the extent
required by the rules of the New York Stock Exchange, "independent" within the
meaning of such rules; and (iii) at such times as an Award under the Plan by the
Company is subject to Section 162(m) of the Code (to the extent relief from the
limitation of Section 162(m) of the Code is sought with respect to Awards and
administration of the Awards by a committee of "outside directors" is required
to receive such relief) "outside directors" within the meaning of Section 162(m)
of the Code.

         "COMMON STOCK" means the common stock, $0.01 par value, of the Company.

         "COMPANY" means Enzo Biochem, Inc., a New York corporation.

         "CONSULTANT" means any person, other than an employee, performing
consulting or advisory services for the Company or any Subsidiary.

         "CONTINUOUS SERVICE" means that the Participant's service with the
Company or a Subsidiary, whether as an employee, Director or Consultant, is not
interrupted or terminated. A Participant's Continuous Service shall not

                                      A-1


be deemed to have been interrupted or terminated merely because of a change in
the capacity in which the Participant renders service to the Company or a
Subsidiary as an employee, Consultant or Director or a change in the entity for
which the Participant renders such service. The Participant's Continuous Service
shall be deemed to have terminated either upon an actual termination or upon the
entity for which the Participant is performing services ceasing to be a
Subsidiary of the Company. The Committee shall determine whether Continuous
Service shall be considered interrupted in the case of any leave of absence
approved by the Company, including sick leave, military leave or any other
personal leave.

         "CORPORATION LAW" means the general corporation law of the jurisdiction
of incorporation of the Company.

         "COVERED EMPLOYEE" means an Eligible Person who is a "covered employee"
within the meaning of Section 162(m)(3) of the Code, or any successor provision
thereto.

         "DIRECTOR" means a member of the Board.

         "DISABILITY" means that a Participant covered by a Company or
Subsidiary-funded long term disability insurance program has incurred a total
disability under such insurance program and a Participant not covered by such an
insurance program has suffered a permanent and total disability within the
meaning of Section 22(e)(3) of the Code or any successor statute thereto.

         "DIVIDEND EQUIVALENT" means a right, granted to a Participant to
receive cash, Common Stock, other Awards or other property equal in value to
dividends paid with respect to a specified number of Common Stock, or other
periodic payments.

         "ELIGIBLE PERSON" means an employee, officer, Director or Consultant to
the Company or a Subsidiary (including an entity that becomes a Subsidiary after
the adoption of the Plan).

         "EXCHANGE ACT" means the Securities Exchange Act of 1934, as amended.

         "FAIR MARKET VALUE" means, on any given date, the current fair market
value of the shares of Common Stock as determined as follows:

                  (i)      If the Common Stock is traded on the New York Stock
Exchange or is listed on a national securities exchange, the closing price for
the day of determination as quoted on such market or exchange which is the
primary market or exchange for trading of the Common Stock or if no trading
occurs on such date, the last day on which trading occurred, or such other
appropriate date as determined by the Committee in its discretion, as reported
in The Wall Street Journal or such other source as the Committee deems reliable;

                  (ii)     If the Common Stock is regularly quoted by a
recognized securities dealer but selling prices are not reported, its Fair
Market Value shall be the mean between the high and the low asked prices for the
Common Stock for the day of determination; or

                  (iii)    In the absence of an established market for the
Common Stock, Fair Market Value shall be determined by the Committee in good
faith.

         "INCENTIVE STOCK OPTION" means an Option (or portion thereof) intended
to qualify for special tax treatment under Section 422 of the Code.

         "NONQUALIFIED STOCK OPTION" means an Option (or portion thereof) which
is not intended or does not for any reason qualify as an Incentive Stock Option.

         "OPTION" means any option to purchase shares of Common Stock granted
under the Plan.

         "PARTICIPANT" means an Eligible Person who is selected by the Committee
to receive an Option, Restricted Stock Award or Restricted Stock Unit Award and
is party to any Stock Option Agreement, Restricted Stock Award

                                      A-2


Agreement or Restricted Stock Unit Award Agreement required by the terms of such
Option, Restricted Stock Award or Restricted Stock Unit Award.

         "PERFORMANCE PERIOD" means that period, if any, established by the
Committee at the time any Award that the Committee determines is to be subject
to the provisions of Section 9 hereof is granted during which any Performance
Objective as specified by the Committee with respect to such Award are to be
measured.

         "PLAN" means this Enzo Biochem, Inc. 2005 Equity Compensation Incentive
Plan.

         "RESTRICTED STOCK AWARD" means an award of Common Stock under Section
7.

         "RESTRICTED STOCK AWARD AGREEMENT" means a written agreement between
the Company and a Participant setting forth the specific terms and conditions of
a Restricted Stock Award granted to the Participant under Section 7. Each
Restricted Stock Award Agreement shall be subject to the terms and conditions of
the Plan and shall include such terms and conditions as the Committee shall
authorize.

         "RESTRICTED STOCK UNIT AWARD" means a right to receive Common Stock,
including Restricted Stock Awards, cash or a combination thereof, at the end of
a specified restricted period.

         "RESTRICTED STOCK UNIT AWARD AGREEMENT" means a written agreement
between the Company and a Participant setting the specific terms and conditions
of a Restricted Stock Unit Award granted to the Participant under Section 8.
Each Restricted Stock Unit Award Agreement shall be subject to the terms and
conditions of the Plan and shall include such terms and conditions as the
Committee shall authorize.

         "SECURITIES ACT" means the Securities Act of 1933 as amended.

         "STOCK OPTION AGREEMENT" means a written agreement between the Company
and a Participant setting forth the specific terms and conditions of an Option
granted to the Participant. Each Stock Option Agreement shall be subject to the
terms and conditions of the Plan and shall include such terms and conditions as
the Committee shall authorize.

         "SUBSIDIARY" means any corporation (other than the Company) in an
unbroken chain of corporations beginning with the Company if each of the
corporations (other than the last corporation in the unbroken chain) owns stock
possessing at least fifty percent (50%) of the total combined voting power of
all classes of stock in one of the other corporations in such chain.

         "TEN PERCENT OWNER" means any Eligible Person owning at the time an
Option is granted more than ten percent (10%) of the total combined voting power
of all classes of stock of the Company or of a Subsidiary. An individual shall,
in accordance with Section 424(d) of the Code, be considered to own any voting
stock owned (directly or indirectly) by or for his brothers, sisters, spouse,
ancestors and lineal descendants and any voting stock owned (directly or
indirectly) by or for a corporation, partnership, estate, trust or other entity
shall be considered as being owned proportionately by or for its shareholders,
partners or beneficiaries.

3.       ADMINISTRATION

         A.       ADMINISTRATION. The Committee shall serve as the administrator
of the Plan. If permitted by the Corporation Law, and not prohibited by the
charter or the bylaws of the Company, the Committee may delegate a portion of
its authority to administer the Plan to an officer or officers of Company
designated by the Committee.

         B.       POWERS OF THE COMMITTEE. Subject to the provisions of the
Plan, and subject at all times to the terms and conditions of the delegation of
authority from the Board, the Committee shall have the authority to implement,
interpret and administer the Plan. Such authority shall include, without
limitation, the authority:

                  (i)      To construe and interpret all provisions of the Plan
and all Stock Option Agreements, Restricted Stock Award Agreements and
Restricted Stock Unit Award Agreements under the Plan.

                                      A-3


                  (ii)     To determine the Fair Market Value of Common Stock.

                  (iii)    To select the Eligible Persons to whom Awards are
granted from time-to-time hereunder.

                  (iv)     To determine the number of shares of Common Stock
covered by an Option, Restricted Stock Award or Restricted Stock Unit Award;
determine whether an Option shall be an Incentive Stock Option or Nonqualified
Stock Option; and determine such other terms and conditions, not inconsistent
with the terms of the Plan, of each Award. Such terms and conditions include,
but are not limited to, the exercise price of an Option, purchase price of
Common Stock subject to a Restricted Stock Award or Restricted Stock Unit Award,
the time or times when Options, Restricted Stock Awards or Restricted Stock Unit
Awards may be exercised or Common Stock issued, the right of the Company to
repurchase Common Stock issued pursuant to the exercise of an Option, or
pursuant to a Restricted Stock Award or Restricted Stock Unit Award, and other
restrictions or limitations (in addition to those contained in the Plan) on the
forfeitability or transferability of Options, Restricted Stock Awards,
Restricted Stock Unit Awards or Common Stock issued pursuant to Awards. Such
terms may include conditions as shall be determined by the Committee and need
not be uniform with respect to Participants.

                  (v)      To amend, cancel, extend, renew, accept the surrender
of, modify or accelerate the vesting of or lapse of restrictions on all or any
portion of an outstanding Option, Restricted Stock Award or Restricted Stock
Unit Award; and to determine the time at which a Restricted Stock Award,
Restricted Stock Unit Award or Common Stock issued under the Plan may become
transferable or nonforfeitable.

                  (vi)     To prescribe the forms of Stock Option Agreements,
Restricted Stock Award Agreements and Restricted Stock Unit Award Agreements; to
adopt policies and procedures for the exercise of Options, Restricted Stock
Awards and Restricted Stock Unit Awards, including the satisfaction of
withholding obligations; to adopt, amend, and rescind policies and procedures
pertaining to the administration of the Plan; and to make all other
determinations necessary or advisable for the administration of the Plan.

                  Any decision  made,  or action  taken,  by the Committee or in
connection with the  administration  of the Plan shall be final,  conclusive and
binding on all persons having an interest in the Plan.

4.       ELIGIBILITY

         A.       ELIGIBILITY FOR AWARDS. Incentive Stock Options may be granted
only to employees of the Company or Subsidiary. Other Awards may be granted to
any Eligible Person selected by the Committee.

         B.       SUBSTITUTION AWARDS. The Committee may make Restricted Stock
Awards, Restricted Stock Unit Awards and may grant Options under the Plan by
assumption, substitution or replacement of stock awards or stock options,
granted by another entity (including a Subsidiary), if such assumption,
substitution or replacement is in connection with an asset acquisition, stock
acquisition, merger, consolidation or similar transaction involving the Company
(and/or its Subsidiary) and such other entity (and/or its Subsidiary).
Notwithstanding any provision of the Plan (other than the maximum number of
shares of Common Stock that may be issued under the Plan), the terms of such
assumed, substituted or replaced Restricted Stock Awards, Restricted Stock Unit
Awards or Options shall be as the Committee, in its discretion, determines is
appropriate.

5.       COMMON STOCK SUBJECT TO PLAN

         A.       SHARE RESERVE AND LIMITATIONS ON GRANTS. Subject to adjustment
as provided in Section 10, the maximum aggregate number of shares of Common
Stock that may be (i) issued under the Plan pursuant to the exercise of Options,
(ii) issued pursuant to Restricted Stock Awards and (iii) issued pursuant to
Restricted Stock Unit Awards is 1,000,000 shares of Common Stock. No Participant
may receive Awards representing more than 200,000 shares in any one calendar
year. This limitation shall be applied as of any date by taking into account the
number of shares available to be made the subject of new Awards as of such date,
plus the number of shares previously issued under the Plan and the number of
shares subject to outstanding Awards as of such date.

                                      A-4


         B.       REVERSION OF SHARES. If an Option, Restricted Stock Award or
Restricted Stock Unit Award is terminated, expires or becomes unexercisable, in
whole or in part, for any reason, the unissued or unpurchased shares of Common
Stock which were subject thereto shall become available for future grant under
the Plan. Shares of Common Stock that have been actually issued under the Plan
shall not be returned to the share reserve for future grants under the Plan;
except that shares of Common Stock issued pursuant to a Restricted Stock Award
or Restricted Stock Unit Award which are repurchased or reacquired by the
Company at the original purchase price of such shares (including, in the case of
shares forfeited back to the Company, no purchase price), shall be returned to
the share reserve for future grant under the Plan. For avoidance of doubt, this
Section 5.B shall not apply to any per Participant limit set forth in Section
5.A.

         C.       SOURCE OF SHARES. Common Stock issued under the Plan may be
shares of authorized and unissued Common Stock or shares of previously issued
Common Stock that have been reacquired by the Company.

         D.       BOOK-ENTRY. Notwithstanding any other provision of the Plan to
the contrary, the Company may elect to satisfy any requirement under the Plan
for the delivery of stock certificates through the use of book-entry.

6.       OPTIONS

         A.       AWARD. In accordance with the provisions of Section 4, the
Committee will designate each Eligible Person to whom an Option is to be granted
and will specify the number of shares of Common Stock covered by such Option.
The Stock Option Agreement shall specify whether the Option is an Incentive
Stock Option or Nonqualified Stock Option, the vesting schedule applicable to
such Option and any other terms of such Option. No Option that is intended to be
an Incentive Stock Option shall be invalid for failure to qualify as an
Incentive Stock Option.

         B.       EXERCISE PRICE. The exercise price per share for Common Stock
subject to an Option shall be determined by the Committee, but shall comply with
the following:

                  (i)      The exercise price per share for Common Stock subject
to a Nonqualified Stock Option shall be not less than one hundred percent (100%)
of the Fair Market Value on the date of grant.

                  (ii)     The exercise price per share for Common Stock subject
to an Incentive Stock Option:

                           (1)      granted to a Participant who is deemed to be
a Ten Percent Owner on the date such option is granted, shall not be less than
one hundred ten percent (110%) of the Fair Market Value on the date of grant.

                           (2)      granted to any other Participant, shall not
be less than one hundred percent (100%) of the Fair Market Value on the date of
grant.

         C.       MAXIMUM OPTION PERIOD. The maximum period during which an
Option may be exercised shall be determined by the Committee on the date of
grant, except that no Option shall be exercisable after the expiration of ten
years from the date such Option was granted. In the case of an Incentive Stock
Option that is granted to a Participant who is or is deemed to be a Ten Percent
Owner on the date of grant, such Option shall not be exercisable after the
expiration of five years from the date of grant. The terms of any Option may
provide that it is exercisable for a period less than such maximum period.

         D.       MAXIMUM VALUE OF OPTIONS WHICH ARE INCENTIVE STOCK OPTIONS. To
the extent that the aggregate Fair Market Value of the Common Stock with respect
to which Incentive Stock Options granted to any person are exercisable for the
first time during any calendar year (under all stock option plans of the Company
or any of its Subsidiaries or parent) exceeds $100,000 (or such other amount
provided in Section 422 of the Code), the Options are not Incentive Stock
Options. For purposes of this Section, the Fair Market Value of the Common Stock
will be determined as of the time the Incentive Stock Option with respect to the
Common Stock is granted. This Section will be applied by taking Incentive Stock
Options into account in the order in which they are granted.

                                      A-5


         E.       NONTRANSFERABILITY. Options granted under the Plan which are
intended to be Incentive Stock Options shall be nontransferable except by will
or by the laws of descent and distribution and during the lifetime of the
Participant shall be exercisable by only the Participant to whom the Incentive
Stock Option is granted. If the Stock Option Agreement so provides or the
Committee so approves, a Nonqualified Stock Option may be transferred by a
Participant through a gift or domestic relations order to the Participant's
family members to the extent in compliance with applicable securities
registration rules. The holder of a Nonqualified Stock Option transferred
pursuant to this Section shall be bound by the same terms and conditions that
governed the Option during the period that it was held by the Participant;
provided that unless the Committee approves a subsequent transfer, such Option
shall be nontransferable by the initial transferee of such Option except by will
or by the laws of descent and distribution. Except to the extent transferability
of a Nonqualified Stock Option is provided for in the Stock Option Agreement or
is approved by the Committee, during the lifetime of the Participant to whom the
Nonqualified Stock Option is granted, such Option may be exercised only by the
Participant. No right or interest of a Participant in any Option shall be liable
for, or subject to, any lien, obligation, or liability of such Participant.

         F.       VESTING AND TERMINATION OF CONTINUOUS SERVICE. Except as
provided in a Stock Option Agreement, the following rules shall apply:

                  (i)      Options will vest as provided in the Stock Option
Agreement. An Option will be exercisable only to the extent that it is vested on
the date of exercise. Vesting of an Option will cease on the date of the
Participant's termination of Continuous Service and the Option will be
exercisable only to the extent the Option is vested on the date of termination
of Continuous Service.

                  (ii)     If the Participant's termination of Continuous
Service is for reason of death or Disability, the right to exercise the Option
(to the extent vested) will expire on the earlier of (a) one (1) year after the
date of the Participant's termination of Continuous Service, or (b) the
expiration date under the terms of the Stock Option Agreement. Until the
expiration date, the Participant or, in the event of the Participant's death
(including death after termination of Continuous Service but before the right to
exercise the Option expires) Participant's heirs, legatees or legal
representative may exercise the Option, except to the extent the Option was
previously transferred pursuant to Section 6.E.

                  (iii)    If the Participant's termination of Continuous
Service is an involuntary termination without Cause or a voluntary termination
(other than a voluntary termination described in Section 6.F(iv)), the right to
exercise the Option (to the extent that it is vested) will expire on the earlier
of (a) three (3) months after the date of the Participant's termination of
Continuous Service, or (b) the expiration date under the terms of the Stock
Option Agreement. If the Participant's termination of Continuous Service is an
involuntary termination without Cause or a voluntary termination (other than a
voluntary termination described in Section 6.F(iv)) and the Participant dies
after his or her termination of Continuous Service but before the right to
exercise the Option has expired, the right to exercise the Option (to the extent
vested) shall expire on the earlier of (x) one (1) year after the date of the
Participant's termination of Continuous Service or (y) the date the Option
expires under the terms of the Stock Option Agreement, and, until expiration,
the Participant's heirs, legatees or legal representative may exercise the
Option, except to the extent the Option was previously transferred pursuant to
Section 6.E.

                  (iv)     If the Participant's termination of Continuous
Service is for Cause or is a voluntary termination at any time after an event
which would be grounds for termination of the Participant's Continuous Service
for Cause, the right to exercise the Option shall expire as of the date of the
Participant's termination of Continuous Service.

         G.       EXERCISE. An Option, if exercisable, shall be exercised by
completion, execution and delivery of notice (written or electronic) to the
Company of the Option which states (i) the Option holder's intent to exercise
the Option, (ii) the number of shares of Common Stock with respect to which the
Option is being exercised, (iii) such other representations and agreements as
may be required by the Company and (iv) the method for satisfying any applicable
tax withholding as provided in Section 10. Such notice of exercise shall be
provided on such form or by such method as the Committee may designate, and
payment of the exercise price shall be made in accordance with Section 6.H.
Subject to the provisions of the Plan and the applicable Stock Option Agreement,
an Option may be exercised to the extent vested in whole at any time or in part
from time to time at such times and in compliance with such requirements as the
Committee shall determine. A partial exercise of an Option shall not affect the
right to

                                      A-6


exercise the Option from time to time in accordance with the Plan and the
applicable Stock Option Agreement with respect to the remaining shares subject
to the Option. An Option may not be exercised with respect to fractional shares
of Common Stock.

         H.       PAYMENT.

                  (i)      Unless otherwise provided by the Stock Option
Agreement, payment of the exercise price for an Option shall be made in cash or
a cash equivalent acceptable to the Committee. The Committee, in its discretion,
may permit payment of all or part of the exercise price of an Option to be made
(a) by surrendering shares of Common Stock to the Company, (b) by the
withholding of shares of Common Stock upon exercise of the Option, (c) if the
Common Stock is traded on an established securities market, payment of the
exercise price by a broker-dealer or by the Option holder with cash advanced by
the broker-dealer if the exercise notice is accompanied by the Option holder's
written irrevocable instructions to deliver the Common Stock acquired upon
exercise of the Option to the broker-dealer; or (d) in such other consideration
as the Committee deems appropriate, or by any combination of the foregoing.

                  (ii)     If Common Stock is used (or withheld) to pay all or
part of the exercise price, the sum of the cash or cash equivalent and the Fair
Market Value (determined as of the date of exercise) of the shares surrendered
must not be less than the exercise price of the shares for which the Option is
being exercised.

                  (iii)    On or after the date any Option [other than an
Incentive Stock Option] is granted, the Committee may determine that payment of
the exercise price may also be made in whole or part in the form of a Restricted
Stock Award or other Common Stock that is subject to a risk of forfeiture or
restrictions on transfer. Unless otherwise determined by the Committee, whenever
the exercise price is paid in whole or in part in accordance with this Section
6.H, the Stock received by the Participant upon such exercise shall be subject
to the same risks of forfeiture or restrictions on transfer as those that
applied to the consideration surrendered by the Participant, provided that such
risks of forfeiture and restrictions on transfer shall apply only to the same
number of shares received by the Participant as applied to the forfeitable or
restricted shares surrendered by the Participant.

         I.       NO REPRICING OF OPTIONS. The Committee may not without the
approval of the shareholders of the Company lower the exercise price of an
outstanding Option, whether by amending the exercise price of the outstanding
Option or through cancellation of the outstanding Option and reissuance of a
replacement or substitute Option; provided that shareholder approval shall not
be required for adjustments made in connection with a capitalization event
described in Section 10.B. in order to prevent enlargement, dilution or
diminishment of rights.

         J.       SHAREHOLDER RIGHTS. No Participant shall have any rights as a
shareholder with respect to shares subject to an Option until the date of
exercise of such Option and the certificate for shares of Common Stock to be
received on exercise of such Option has been issued by the Company.

         K.       DISPOSITION. A Participant shall notify the Company of any
sale or other disposition of Common Stock acquired pursuant to an Incentive
Stock Option if such sale or disposition occurs (i) within two years of the
grant of an Option or (ii) within one year of the issuance of the Common Stock
to the Participant. Such notice shall be in writing and directed to the
Secretary of the Company.

7.       RESTRICTED STOCK AWARDS

         Each Restricted Stock Award Agreement for a Restricted Stock Award
shall be in such form and shall contain such terms and conditions as the
Committee shall deem appropriate. The terms and conditions of the Restricted
Stock Award Agreements for Restricted Stock Awards may change from time to time,
and the terms and conditions of separate Restricted Stock Awards need not be
identical, but each Restricted Stock Award shall include (through incorporation
of the provisions hereof by references in the agreement or otherwise) the
substance of each of the following provisions:

         A.       PURCHASE PRICE. The Committee may establish a purchase price
for Common Stock subject to a Restricted Stock Award.

                                      A-7


         B.       CONSIDERATION. The purchase price, if any, of Common Stock
acquired pursuant to the Restricted Stock Award shall be paid either: (a) in
cash at the time of purchase, or (b) in any other form of legal consideration
that may be acceptable to the Committee in its discretion.

         C.       VESTING. Shares of Common Stock acquired under a Restricted
Stock Award may, but need not, be subject to a share repurchase option in favor
of the Company in accordance with a vesting schedule to be determined by the
Committee. Any grant or the vesting thereon may be further conditioned upon the
attainment of Performance Objectives established by the Committee, as defined in
Section 9 herein.

                  (i)      PARTICIPANT'S TERMINATION OF SERVICE OR FAILURE OF
VESTING. In the event of termination of a Participant's Continuous Service
before vesting or other failure of the Common Stock to vest, then, unless
otherwise provided in the Restricted Stock Award Agreement, the Participant
shall forfeit shares of Common Stock held by the Participant under the terms of
a Restricted Stock Award which have not vested and for which no purchase price
was paid by the Participant and the Company may repurchase or otherwise
reacquire (including by way of forfeiture by the Participant) any or all of the
shares of Common Stock held by the Participant which have not vested under the
terms of the Restricted Stock Award Agreement for such Restricted Stock Award
and for which a purchase price was paid by the Participant at the purchase price
paid by the Participant.

                  (ii)     TRANSFERABILITY. Rights to acquire shares of Common
Stock under a Restricted Stock Award shall be transferable by the Participant
only upon such terms and conditions as are set forth in the Restricted Stock
Award Agreement for such Restricted Stock Award, as the Committee shall
determine in its discretion, so long as Common Stock granted under the
Restricted Stock Award remains subject to the terms of the Restricted Stock
Award Agreement.

                  (iii)    ADDITIONAL RIGHTS. Any grant may require that any or
all dividends or other distributions paid on the shares acquired under a
Restricted Stock Award during the period of such restrictions be automatically
sequestered and reinvested on an immediate or deferred basis in additional
shares of Common Stock which may be subject to the same restrictions as the
underlying Award or such other restrictions as the Committee shall determine.
Unless provided otherwise in the Restricted Stock Award Agreement, Participants
holding shares of Common Stock subject to restrictions under a Restricted Stock
Award Agreement may exercise full voting rights with respect to the shares.

         D.       FORFEITURE. Except as otherwise determined by the Committee,
upon termination of a Participant's Continuous Service during the applicable
restricted period or portion thereof to which forfeiture conditions apply (as
provided in the Restricted Stock Award Agreement), the Participant's Restricted
Stock Award that is at that time subject to a risk of forfeiture that has not
lapsed or otherwise been satisfied shall be forfeited; provided that the
Committee may provide, by rule or regulation or in any Restricted Stock Award
Agreement, or may determine in any individual case, that forfeiture conditions
relating to a Restricted Stock Award shall be waived in whole or in part in the
event of terminations resulting from specified causes, and the Committee may in
other cases waive in whole or in part the forfeiture of any Restricted Stock
Award.

8.       RESTRICTED STOCK UNIT AWARDS.

         Each Restricted Stock Unit Award Agreement for a Restricted Stock Unit
Award shall be in such form and shall contain such terms and conditions as the
Committee shall deem appropriate. The terms and conditions of the Restricted
Stock Unit Award Agreements for Restricted Stock Unit Awards may change from
time to time, and the terms and conditions of separate Restricted Stock Unit
Awards need not be identical, but each Restricted Stock Unit Award shall include
(through incorporation of the provisions hereof by references in the agreement
or otherwise) the substance of each of the following provisions:

         A.       AWARD AND RESTRICTIONS. Satisfaction of a Restricted Stock
Unit Award shall occur upon expiration of the restricted period specified for
such Restricted Stock Unit Award by the Committee (or, if permitted by the
Committee, as elected by the Participant). In addition, a Restricted Stock Unit
Award shall be subject to such restrictions (which may include a risk of
forfeiture) as the Committee may impose, if any, which restrictions may lapse at
the expiration of the restricted period or at earlier specified times (including
based on achievement of Performance Objectives as defined in Section 9 herein
and/or future service requirements), separately or in

                                      A-8


combination, in installments or otherwise, as the Committee may determine. A
Restricted Stock Unit Award may be satisfied by delivery of Common Stock, cash
equal to the Fair Market Value of the specified number of shares of Common Stock
covered by the Restricted Stock Unit Award, a combination thereof, as determined
by the Committee at the date of grant or thereafter. Prior to satisfaction of a
Restricted Stock Unit Award, a Restricted Stock Unit Award carries no voting or
dividend or other rights associated with Common Stock ownership.

         B.       FORFEITURE. Except as otherwise determined by the Committee,
upon termination of a Participant's Continuous Service during the applicable
restricted period or portion thereof to which forfeiture conditions apply (as
provided in the Restricted Stock Unit Award Agreement), the Participant's
Restricted Stock Unit Awards that is at that time subject to a risk of
forfeiture that has not lapsed or otherwise been satisfied shall be forfeited;
provided that the Committee may provide, by rule or regulation or in any
Restricted Stock Unit Award Agreement, or may determine in any individual case,
that forfeiture conditions relating to a Restricted Stock Unit Award shall be
waived in whole or in part in the event of terminations resulting from specified
causes, and the Committee may in other cases waive in whole or in part the
forfeiture of any Restricted Stock Unit Award.

         C.       DIVIDEND EQUIVALENTS. The Committee, in its discretion, may
grant Dividend Equivalents in conjunction with grants of Restricted Stock Unit
Awards. Unless otherwise determined by the Committee at date of grant, any
Dividend Equivalents that are granted with respect to any Restricted Stock Unit
Awards shall be either (A) paid with respect to such Restricted Stock Unit
Awards at the dividend payment date in cash or in Shares of unrestricted stock
having a Fair Market Value equal to the amount of such dividends, or (B)
deferred with respect to such Restricted Stock Unit Awards and the amount or
value thereof automatically deemed reinvested in additional Restricted Stock
Unit Awards, other Awards or other investment vehicles, as the Committee shall
determine or permit the Participant to elect.

         D.       TRANSFERABILITY. Rights to acquire shares of Common Stock
under a Restricted Stock Unit Award shall be transferable by the Participant
only upon such terms and conditions as are set forth in the Restricted Stock
Unit Award Agreement for such Restricted Stock Unit Award, as the Committee
shall determine in its discretion, so long as Common Stock granted under the
Restricted Stock Unit Award remains subject to the terms of the Restricted Stock
Award Unit Agreement.

9.       CODE SECTION 162(m) PROVISIONS.

         A.       COVERED EMPLOYEES. The Committee, in its discretion, may
determine at the time an Award is granted to an Eligible Person who is, or is
likely to be, as of the end of the tax year in which the Company would claim a
tax deduction in connection with such Award, a Covered Employee, that the
provisions of this Section 9 shall be applicable to such Award.

         B.       PERFORMANCE OBJECTIVES. If an Award is subject to this Section
9, then the lapsing of restrictions thereon and the distribution of cash, shares
or other property pursuant thereto, as applicable, shall be contingent upon
achievement of one or more performance objectives. Performance Objectives shall
meet the requirements of Section 162(m) of the Code and regulations thereunder
including the requirement that the level or levels of performance targeted by
the Committee result in the achievement of performance goals being
"substantially uncertain." One or more of the following business criteria for
the Company, on a consolidated basis, and/or a Subsidiary, or for business or
geographical units of the Company and/or a Subsidiary (except with respect to
the total shareholder return and earnings per share criteria), shall be used by
the Committee in establishing performance objectives for such Awards: (1)
earnings per share; (2) revenues or margins; (3) cash flow; (4) operating
margin; (5) return on net assets, investment, capital, or equity; (6) economic
value added; (7) direct contribution; (8) net income; pretax earnings; earnings
before interest and taxes; earnings before interest, taxes, depreciation and
amortization; earnings after interest expense and before extraordinary or
special items; operating income; income before interest income or expense,
unusual items and income taxes, local, state or federal and excluding budgeted
and actual bonuses which might be paid under any ongoing bonus plans of the
Company; (9) working capital; (10) management of fixed costs or variable costs;
(11) identification or consummation of investment opportunities or completion of
specified projects in accordance with corporate business plans, including
strategic mergers, acquisitions or divestitures; (12) total shareholder return;
and (13) debt reduction. Any of the above goals may be determined on an absolute
or relative basis or as compared to the performance of a published or special
index deemed applicable by the Committee including, but not limited to, the
Standard & Poor's 500 Stock Index or a

                                      A-9


group of companies that are comparable to the Company. The Committee shall
exclude the impact of an event or occurrence which the Committee determines
should appropriately be excluded, including without limitation (i)
restructurings, discontinued operations, extraordinary items, and other unusual
or non-recurring charges, (ii) an event either not directly related to the
operations of the Company or not within the reasonable control of the Company's
management, or (iii) a change in accounting standards required by generally
accepted accounting principles.

         C.       PERFORMANCE PERIOD; TIMING FOR ESTABLISHING PERFORMANCE GOALS.
Achievement of Performance Objectives in respect of any applicable Award shall
be measured over a Performance Period no shorter than 12 months and no longer
than five years, as specified by the Committee. Performance Objectives shall be
established not later than 90 days after the beginning of any Performance Period
applicable to such Awards, or at such other date as may be required or permitted
for "performance-based compensation" under Code Section 162(m).

         D.       ADJUSTMENTS. The Committee may, in its discretion, reduce the
amount of a settlement otherwise to be made in connection with Awards subject to
this Section 9, but may not exercise discretion to increase any such amount
payable to a Covered Employee in respect of an Award subject to this Section 9.
The Committee shall specify the circumstances in which such Awards shall be paid
or forfeited in the event of termination of Continuous Service by the
Participant prior to the end of a Performance Period or settlement of Awards.

         E.       COMMITTEE CERTIFICATION. No Participant shall receive any
payment under the Plan unless the Committee has certified, by resolution or
other appropriate action in writing, that the performance criteria and any other
material terms previously established by the Committee or set forth in the Plan,
have been satisfied to the extent necessary to qualify as "performance based
compensation" under Code Section 162(m).

10.      CHANGES IN CAPITAL STRUCTURE

         A.       NO LIMITATIONS OF RIGHTS. The existence of outstanding
Options, Restricted Stock Awards, or Restricted Stock Unit Awards shall not
affect in any way the right or power of the Company or its shareholders to make
or authorize any or all adjustments, recapitalizations, reorganizations or other
changes in the Company's capital structure or its business, or any merger or
consolidation of the Company, or any issuance of bonds, debentures, preferred or
prior preference stock ahead of or affecting the Common Stock or the rights
thereof, or the dissolution or liquidation of the Company, or any sale or
transfer of all or any part of its assets or business, or any other corporate
act or proceeding, whether of a similar character or otherwise.

         B.       CHANGES IN CAPITALIZATION. If the Company shall effect (i) any
stock dividend, stock split, subdivision or consolidation of shares,
recapitalization or other capital readjustment, (ii) any merger consolidation,
separation of the Company (including a spin-off or split-up), reorganization,
partial or complete liquidation or other distribution of assets (other than
ordinary dividends or distributions) without receiving consideration therefore
in money, services or property, or (iii) any other corporate transaction having
a similar effect, then (iv) the number, class, and per share price or base
amount of shares of Common Stock subject to outstanding Options, Restricted
Stock Awards and Restricted Stock Unit Awards shall be equitably adjusted by the
Committee as it in good faith determines is required in order to prevent
enlargement, dilution, or diminishment of rights, (v) the number and class of
shares of Common Stock then reserved for issuance under the Plan and the maximum
number of shares for which Awards may be granted to a Participant during a
specified time period shall be adjusted as the Committee deems appropriate to
reflect such transaction, and (vi) the Committee shall make such modifications
to the Performance Objectives for each outstanding applicable Award as the
Committee determines are appropriate in accordance with Section 9. The
conversion of convertible securities of the Company shall not be treated as
effected "without receiving consideration." The Committee shall make such
adjustments, and its determinations shall be final, binding and conclusive.

         C.       MERGER, CONSOLIDATION OR ASSET SALE. If the Company (i) is
dissolved, liquidated, merged or consolidated with another entity, (ii) sells or
otherwise disposes of substantially all of its assets to another entity or (iii)
engages in any transaction (including without limitation a merger or
reorganization in which the Company is the surviving entity) that results in any
person or entity (other than persons who are shareholders or Subsidiaries
immediately prior to the transaction) owning fifty percent (50%) or more of the
combined voting power of all classes of stock of the Company, while Options,
Restricted Stock Awards or Restricted Stock Unit Awards remain

                                      A-10


outstanding under the Plan, unless provisions are made in connection with such
transaction for the continuance of the Plan and/or the assumption or
substitution of such Options, Restricted Stock Awards or Restricted Stock Unit
Awards with new options, stock awards or stock unit awards covering the stock of
the successor entity, or parent or Subsidiary thereof, with appropriate
adjustments as to the number and kind of shares and prices, then all outstanding
Options, Restricted Stock Awards and Restricted Stock Unit Awards which have not
been continued, assumed or for which a substituted award has not been granted
shall become exercisable immediately prior to and terminate immediately as of
the effective date of any such merger, consolidation, sale, or other applicable
transaction. In the alternative, the Board may elect, in its sole discretion, to
cancel any outstanding Options, Restricted Stock Awards and Restricted Stock
Unit Awards and pay or deliver, or cause to be paid or delivered, to the holder
thereof an amount in cash or securities having a value (as determined by the
Board acting in good faith), in the case of Restricted Stock Awards and
Restricted Stock Unit Awards, equal to the formula or fixed price per share paid
to holders of shares of Stock and, in the case of Options, equal to the product
of the number of shares of Stock subject to the Option multiplied by the amount,
if any, by which (A) the formula or fixed price per share paid to holders of
shares of Stock pursuant to such transaction exceeds (B) the exercise price
applicable to such Option.

         D.       LIMITATION ON ADJUSTMENT. Except as previously expressly
provided, neither the issuance by the Company of shares of stock of any class,
or securities convertible into shares of stock of any class, for cash or
property, or for labor or services either upon direct sale or upon the exercise
of rights or warrants to subscribe therefor, or upon conversion of shares or
obligations of the Company convertible into such shares or other securities, nor
the increase or decrease of the number of authorized shares of stock, nor the
addition or deletion of classes of stock, shall affect, and no adjustment by
reason thereof shall be made with respect to, the number, class or price of
shares of Common Stock then subject to outstanding Options, Restricted Stock
Awards or Restricted Stock Unit Awards.

11.      WITHHOLDING OF TAXES

         The Company or a Subsidiary shall have the right, before any
certificate for any Common Stock is delivered, to deduct or withhold from any
payment owed to a Participant any amount that is necessary in order to satisfy
any withholding requirement that the Company or Subsidiary in good faith
believes is imposed upon it in connection with Federal, state, or local taxes,
including transfer taxes, as a result of the issuance of, or lapse of
restrictions on, such Common Stock, or otherwise require such Participant to
make provision for payment of any such withholding amount. Subject to such
conditions as may be established by the Committee, the Committee may permit a
Participant to (i) have Common Stock otherwise issuable under an Option,
Restricted Stock Award or Restricted Stock Unit Award withheld to the extent
necessary to comply with minimum statutory withholding rate requirements for
supplemental income, (ii) tender back to the Company shares of Common Stock
received pursuant to an Option, Restricted Stock Award or Restricted Stock Unit
Award to the extent necessary to comply with minimum statutory withholding rate
requirements for supplemental income, (iii) deliver to the Company previously
acquired Common Stock, (iv) have funds withheld from payments of wages, salary
or other cash compensation due the Participant, or (v) pay the Company or its
Subsidiary in cash, in order to satisfy part or all of the obligations for any
taxes required to be withheld or otherwise deducted and paid by the Company or
its Subsidiary with respect to the Option, Restricted Stock Award or Restricted
Stock Unit Award.

12.      COMPLIANCE WITH LAW AND APPROVAL OF REGULATORY BODIES

         A.       GENERAL REQUIREMENTS. No Option, Restricted Stock Award or
Restricted Stock Unit Award shall be exercisable, no Common Stock shall be
issued, no certificates for shares of Common Stock shall be delivered, and no
payment shall be made under the Plan except in compliance with all applicable
federal and state laws and regulations (including, without limitation,
withholding tax requirements), any listing agreement to which the Company is a
party, and the rules of all domestic stock exchanges or quotation systems on
which the Company's shares may be listed. The Company shall have the right to
rely on an opinion of its counsel as to such compliance. Any share certificate
issued to evidence Common Stock when a Restricted Stock Award or Restricted
Stock Unit Award is granted or for which an Option, Restricted Stock Award or
Restricted Stock Unit Award is exercised may bear such legends and statements as
the Committee may deem advisable to assure compliance with federal and state
laws and regulations. No Option, Restricted Stock Award or Restricted Stock Unit
Award shall be exercisable, no Restricted Stock Award or Restricted Stock Unit
Award shall be granted, no Common Stock shall be issued, no certificate for
shares shall be delivered, and no payment shall be made under the Plan until the
Company has

                                      A-11


obtained such consent or approval as the Committee may deem advisable from
regulatory bodies having jurisdiction over such matters.

         B.       PARTICIPANT REPRESENTATIONS. The Committee may require that a
Participant, as a condition to receipt or exercise of a particular award,
execute and deliver to the Company a written statement, in form satisfactory to
the Committee, in which the Participant represents and warrants that the shares
are being acquired for such person's own account, for investment only and not
with a view to the resale or distribution thereof. The Participant shall, at the
request of the Committee, be required to represent and warrant in writing that
any subsequent resale or distribution of shares of Common Stock by the
Participant shall be made only pursuant to either (i) a registration statement
on an appropriate form under the Securities Act of 1933, which registration
statement has become effective and is current with regard to the shares being
sold, or (ii) a specific exemption from the registration requirements of the
Securities Act of 1933, but in claiming such exemption the Participant shall,
prior to any offer of sale or sale of such shares, obtain a prior favorable
written opinion of counsel, in form and substance satisfactory to counsel for
the Company, as to the application of such exemption thereto.

13.      GENERAL PROVISIONS

         A.       EFFECT ON EMPLOYMENT AND SERVICE. Neither the adoption of the
Plan, its operation, nor any documents describing or referring to the Plan (or
any part thereof) shall (i) confer upon any individual any right to continue in
the employ or service of the Company or a Subsidiary, (ii) in any way affect any
right and power of the Company or a Subsidiary to change an individual's duties
or terminate the employment or service of any individual at any time with or
without assigning a reason therefor, or (iii) except to the extent the Committee
grants an Option, Restricted Stock Award or Restricted Stock Unit Award to such
individual, confer on any individual the right to participate in the benefits of
the Plan.

         B.       USE OF PROCEEDS. The proceeds received by the Company from the
sale of Common Stock pursuant to the Plan shall be used for general corporate
purposes.

         C.       UNFUNDED PLAN. The Plan, insofar as it provides for grants,
shall be unfunded, and the Company shall not be required to segregate any assets
that may at any time be represented by grants under the Plan. Any liability of
the Company to any person with respect to any grant under the Plan shall be
based solely upon any contractual obligations that may be created pursuant to
the Plan. No such obligation of the Company shall be deemed to be secured by any
pledge of, or other encumbrance on, any property of the Company.

         D.       FURTHER RESTRICTIONS ON TRANSFER. Any Award made under the
Plan may expressly provide that all or any part of the shares of Common Stock
that are: (i) to be issued or transferred by the Company upon the exercise of an
Option, (ii) no longer subject to a substantial risk of forfeiture and
restrictions on transfer referred to in Section 7 of the Plan, or (iii) subject
to a restricted period referred to in Section 8 of the Plan, shall be subject to
further restrictions on transfer.

         E.       FRACTIONAL SHARES. The Company shall not be required to issue
fractional shares pursuant to the Plan. The Committee may provide for
elimination of fractional shares or the settlement of such fraction shares in
cash.

         F.       RULES OF CONSTRUCTION. Headings are given to the Sections of
the Plan solely as a convenience to facilitate reference, and shall not be used
in interpreting, construing or enforcing any provision hereof. The reference to
any statute, regulation, or other provision of law shall be construed to refer
to any amendment to or successor of such provision of law. To the extent that
any provision of the Plan would prevent any Option that was intended to qualify
under particular provisions of the Code from so qualifying, such provision of
the Plan shall be null and void with respect to such Option, provided that such
provision shall remain in effect with respect to other Options, and there shall
be no further effect on any provision of the Plan.

         G.       CODE SECTION 409A. If and to the extent that the Committee
believes that any Awards may constitute a "nonqualified deferred compensation
plan" under Section 409A of the Code, the terms and conditions

                                      A-12


set forth in the Award Agreement for that Award shall be drafted in a manner
that is intended to comply with, and shall be interpreted in a manner consistent
with, the applicable requirements of Section 409A of the Code.

         H.       FOREIGN EMPLOYEES. In order to facilitate the making of any
grant or combination of grants under the Plan, the Committee may provide for
such special terms for Awards to Participants who are foreign nationals, or who
are employed by the Company or any subsidiary outside of the United States, as
the Committee may consider necessary or appropriate to accommodate differences
in local law, tax policy or custom. Moreover, the Committee may approve such
supplements to, or amendments, restatements or alternative versions of, the Plan
as it may consider necessary or appropriate for such purposes without thereby
affecting the terms of the Plan, as then in effect, unless the Plan could have
been amended to eliminate such inconsistency without further approval by the
Shareholders of the Company.

         I.       CHOICE OF LAW. The Plan and all Stock Option Agreements,
Restricted Stock Award Agreements and Restricted Stock Unit Award Agreements
entered into under the Plan (except to the extent that any such Stock Option
Agreement, Restricted Stock Award Agreement or Restricted Stock Unit Award
Agreement otherwise provides) shall be governed by and interpreted under the
laws of the jurisdiction of incorporation of the Company excluding (to the
greatest extent permissible by law) any rule of law that would cause the
application of the laws of any jurisdiction other than the laws of the
jurisdiction of incorporation of the Company.

14.      AMENDMENT AND TERMINATION

         The Board may amend or terminate the Plan from time to time; provided,
however, that with respect to any amendment that (i) increases the aggregate
number of shares of Common Stock that may be issued under the Plan, (ii) changes
the class of employees eligible to receive Incentive Stock Options or (iii) if
shareholder approval is required by the terms of any applicable law, regulation,
or rule, including, without limitation, any rule of the New York Stock Exchange,
or any national securities exchange on which the Common Stock is publicly
traded, each such amendment shall be subject to the approval of the shareholders
of the Company. Except as specifically permitted by a provision of the Plan
(other than Section 3.B.), the Stock Option Agreement, Restricted Stock Award
Agreement or Restricted Stock Unit Award Agreement or as required to comply with
applicable law, regulation or rule, no amendment to the Plan or a Stock Option
Agreement, Restricted Stock Award Agreement or Restricted Stock Unit Award
Agreement shall, without a Participant's consent, adversely affect any rights of
such Participant under any Option, Restricted Stock Award or Restricted Stock
Unit Award outstanding at the time such amendment is made; provided, however,
that an amendment that may cause an Incentive Stock Option to become a
Nonqualified Stock Option, and any amendment that is required to comply with the
rules applicable to Incentive Stock Options, shall not be treated as adversely
affecting the rights of the Participant.

15.      EFFECTIVE DATE AND DURATION OF PLAN

         A.       The Plan became effective upon adoption by the Board, subject
to approval within twelve (12) months by the shareholders holding of a majority
of the shares of entitled to vote thereon. Unless and until the plan has been
approved the shareholders of the Company, no Option, Restricted Stock Award or
Restricted Stock Unit Award may be exercised, and no shares of Common Stock may
be issued under the Plan. In the event that the shareholders of the Company
shall not approve the Plan within such twelve (12) month period, the Plan and
any previously granted Option, Restricted Stock Award or Restricted Stock Unit
Award shall terminate.

         B.       Unless previously terminated, the Plan will terminate ten (10)
years after the earlier of (i) the date the Plan is adopted by the Board, or
(ii) the date the Plan is approved by the shareholders, except that Options,
Restricted Stock Awards and Restricted Stock Unit Awards that are granted under
the Plan prior to its termination will continue to be administered under the
terms of the Plan until the Options, Restricted Stock Awards and Restricted
Stock Unit Awards terminate or are exercised.

                                      A-13




                                      PROXY

                               ENZO BIOCHEM, INC.
               60 EXECUTIVE BOULEVARD, FARMINGDALE, NEW YORK 11735

           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The  undersigned  hereby appoints Melvin F. Lazar and Shahram K. Rabbani as
Proxies,  each with the power to appoint his substitute,  and hereby  authorizes
them to represent and to vote, as designated below, all the shares of the Common
Stock of Enzo Biochem,  Inc. held of record by the  undersigned  on November 23,
2005, at the Annual  Meeting of  Shareholders  to be held on January 19, 2006 or
any adjournment thereof.

PROPOSAL 1.  Election  of Elazar  Rabbani,  Ph.D.,  John B.  Sias and  Marcus A.
             Conant, M.D. as Class III Directors.

             |_| FOR all nominees                      |_| WITHHOLDING AUTHORITY
                 (except as marked to the                  as to all nominees
                 contrary below)

             (INSTRUCTION:  To  withhold  authority to  vote for any  individual
             nominee, print that nominee's name on the line provided below.)

             Withheld for: _____________________________________________

PROPOSAL 2. To ratify and approve the amendment and restatement of the Company's
            2005  Equity  Compensation  Incentive Plan among other things to (a)
            permit  restricted  stock unit  awards  to  be  made under the plan,
            (b)  add  specific  performance  criteria  that   may   be  used  to
            establish  performance  objectives  for  awards  intended to qualify
            as  "performance-based  compensation"  under  Section  162(m) of the
            Internal  Revenue  Code  of  1986,  as  amended,  and (c)  eliminate
            automatic  annual  option  grants  to  the   Company's  non-employee
            directors.

            |_| FOR                    |_| AGAINST                   |_| ABSTAIN

PROPOSAL 3. To ratify  the  appointment  of Ernst & Young  LLP as the  Company's
            independent  registered  public  accounting  firm  for the Company's
            fiscal year ending July 31, 2006.

            |_| FOR                    |_| AGAINST                   |_| ABSTAIN

     In their  discretion,  the Proxies are  authorized  to vote upon such other
business  as may  properly  come  before  the  Annual  Meeting.  This proxy when
properly executed will be voted in the manner directed herein by the undersigned
shareholder.  If no direction is made, this proxy will be voted FOR Proposals 1,
2 and 3.

     PLEASE SIGN EXACTLY AS NAME APPEARS BELOW.  WHEN SHARES OF COMMON STOCK ARE
HELD BY JOINT TENANTS, BOTH SHOULD SIGN.


                    Dated:___________________________ , 2005 / 2006 (circle one)



                    Signature:______________________________


                    Signature  if held  jointly:  ______________________________
                    (When signing as attorney,  as executor,  as  administrator,
                    trustee or  guardian,  please give full title as such.  If a
                    corporation, please sign in full corporate name by President
                    or other authorized officer.  If a partnership,  please sign
                    in partnership name by authorized person.)