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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934
(Amendment No. 2 )*

Sequenom, Inc.
(Name of Issuer)
Common Stock, par value $0.001 per share
(Title of Class of Securities)
817337108
(CUSIP Number)
Kevin M. Royer, Esq.
Siemens Corporation
153 East 53 Street, 56th Floor
New York, NY 10022
(212) 258-4151
(Name, Address and Telephone Number of Person Authorized to
Receive Notices and Communications)
May 28, 2008
(Date of Event Which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. o

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7(b) for other parties to whom copies are to be sent.

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not
required to respond unless the form displays a currently valid OMB control number.

 
 

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SCHEDULE 13D
                     
CUSIP No.
  
859823106 
  

 

           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Venture Capital GmbH
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
  (a)   o 
  (b)   þ 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS
   
  OO
     
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Federal Republic of Germany
       
  7   SOLE VOTING POWER
     
NUMBER OF   2,920,342
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   2,920,342
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  2,920,342
     
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  6.43%
     
14   TYPE OF REPORTING PERSON
   
  CO

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SCHEDULE 13D
                     
CUSIP No.
  
859823106 
  

 

           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Beteiligungen Inland GmbH
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
  (a)   o 
  (b)   þ 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS
   
  OO
     
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Federal Republic of Germany
       
  7   SOLE VOTING POWER
     
NUMBER OF   2,920,342
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   2,920,342
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  2,920,342
     
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  6.43%
     
14   TYPE OF REPORTING PERSON
   
  CO

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SCHEDULE 13D
                     
CUSIP No.
  
859823106 
  

 

           
1   NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

Siemens Aktiengesellschaft
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

  (a)   o 
  (b)   þ 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS
   
  OO
     
5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Federal Republic of Germany
       
  7   SOLE VOTING POWER
     
NUMBER OF   2,920,342
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   2,920,342
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  2,920,342
     
12   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  6.43%
     
14   TYPE OF REPORTING PERSON
   
  CO

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     Item 5. Interest in Securities of the Issuer
SIGNATURE

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     This Amendment No. 2 (the “Amendment No. 2”) amends and supplements Item 5 of the Statement of Beneficial Ownership on Schedule 13D originally filed with the Securities and Exchange Commission on June 12, 2006, as amended by Amendment No. 1 filed on May 21, 2008 (together, the “Schedule 13D”) relating to the beneficial ownership by Siemens Venture Capital GmbH (“Siemens Venture Capital”), Siemens Beteiligungen Inland GmbH (“Siemens Beteiligungen”) and Siemens Aktiengesellschaft (“Siemens AG”) (each, individually, a “Reporting Person” and collectively the “Reporting Persons”) of common stock, par value $0.001 per share (the “Common Stock”) of Sequenom, Inc., a Delaware corporation with principal executive offices at 3595 John Hopkins Court, San Diego, California 92121. (the “Issuer”). Unless specifically amended in this Amendment No. 2, the disclosures set forth in the Schedule 13D shall remain unchanged.
     Item 5. Interest in Securities of the Issuer
     (a)-(b) As of May 28, 2008, Siemens Venture Capital beneficially owns 2,920,342 shares of Common Stock, representing approximately 6.43% of shares of Common Stock outstanding as of April 14, 2008. Siemens Venture Capital has sole voting and dispositive power with respect to such shares. For purposes of this Statement, Siemens AG and Siemens Beteiligungen are also reported as having voting and dispositive power over such shares by virtue of their respective control over Siemens Venture Capital. Siemens Beteiligungen, as Siemens Venture Capital’s sole shareholder, and Siemens AG, as Siemens Beteiligungen’s sole shareholder, may be deemed to own all such shares.
     To the best of the Reporting Persons’ knowledge, none of the persons set forth in Exhibit B to Amendment No. 1 filed on May 21, 2008 beneficially owns any shares of Common Stock.
     (c) Except as set forth below, there were no purchases by any of the Reporting Persons, or to the best of the Reporting Persons’ knowledge, any of the persons set forth in Exhibit B to Amendment No. 1 filed on May 21, 2008, since May 21, 2008:
                         
Reporting Person                
who effected the   Date of   Number of   Price Per   Type of
Transaction   Transaction   Shares   Share   Transaction
 
Siemens Venture
Capital GmbH
  May 21, 2008     258,221     $ 7.4036     Open Market Sale
Siemens Venture
Capital GmbH
  May 22, 2008     19,348     $ 7.417     Open Market Sale
Siemens Venture
Capital GmbH
  May 27, 2008     61,800     $ 7.4193     Open Market Sale
Siemens Venture
Capital GmbH
  May 28, 2008     125,400     $ 7.4454     Open Market Sale
     (d) Not applicable.
     (e) Not applicable.

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SIGNATURE
     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens Venture Capital GmbH is true, complete and correct.
Dated: May 30, 2008
         
  SIEMENS VENTURE CAPITAL GMBH
 		  
  By:   /s/ DR. RALF SCHNELL    
    Name:   Dr. Ralf Schnell   
    Title:   CEO   
 
     
  By:   /s/ THOMAS KOLBINGER    
    Name:   Thomas Kolbinger   
    Title:   CFO   

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     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens Beteiligungen Inland GmbH is true, complete and correct.
Dated: May 30, 2008
         
  SIEMENS BETEILIGUNGEN INLAND GMBH
 		  
  By:   /s/ CHRISTIAN HOMERING    
    Name:   Christian Homering   
    Title:   Managing Director   
 
     
  By:   /s/ DR. OTMAR N. SCHMITT    
    Name:   Dr. Otmar N. Schmitt   
    Title:   Managing Director   

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     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Siemens AG is true, complete and correct.
Dated: May 30, 2008
         
  SIEMENS AKTIENGESELLSCHAFT
 		  
  By:   /s/ DOMINIK ASAM    
    Name:   Dominik Asam   
    Title:   Managing Director and CEO  
      Siemens Financial Services GmbH   
 
     
  By:   /s/ SOLMS U. WITTIG    
    Name:   Solms U. Wittig   
    Title:   General Counsel Corporate and SFS   
 

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