Washington, D.C. 20549

                                   FORM 12b-25

                        Commission File Number: 002-78682

                           NOTIFICATION OF LATE FILING

                   |_| Form 10-K |_| Form 20-F |_| Form 11-K
                   |X| Form 10-Q |_| Form 10-D |_| Form N-SAR

For Period Ended: December 31, 2006

|_| Transition Report on Form 10-K
|_| Transition Report on Form 20-F
|_| Transition Report on Form 11-k
|_| Transition Report on Form 10-Q
|_| Transition Report on Form N-SAR

For the Transition Period Ended:__________________

Nothing  in this  form  shall be  construed  to imply  that the  Commission  has
verified any information contained herein.

If the notification  relates to a portion of the filing checked above,  identify
the item(s) to which the notification relates:



Applied DNA Sciences, Inc.
Full name of registrant

Former name if applicable

25 Health Sciences Drive, Suite 113
Address of principal executive office

Stony Brook, New York 11790
City, state and zip code

PART II - RULE 12b-25 (b) AND (c)

If the subject report could not be filed without  unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

    | (a) The reasons  described in  reasonable  detail in Part III of this form
    | could not be eliminated without unreasonable effort or expense;
    | (b) The subject annual report,  semi-annual  report,  transition report on
    | Form 10-K,  Form 20-F,  Form 11-K,  Form N-SAR or Form  N-CSR,  or portion
    | thereof,  will be filed on or before the fifteenth  calendar day following
[X] | the  prescribed  due date; or the subject  quarterly  report or transition
    | report on Form  10-Q or  subject  distribution  report  on Form  10-D,  or
    | portion  thereof,  will be filed  on or  before  the  fifth  calendar  day
    | following the prescribed due date; and
    | (c) The accountant's statement or other exhibit required by Rule 12b-25(c)
    | has been attached if applicable.


State below in reasonable  detail the reasons why Forms 10-K,  20-F, 11-K, 10-Q,
10-D, N-SAR,  N-CSR, or the transition report, or portion thereof,  could not be
filed within the prescribed time period.

      Applied DNA Sciences,  Inc. (the "Company") is filing this Notification of
Late Filing on Form 12b-25 with  respect to the  Company's  Quarterly  Report on
Form 10-QSB for the quarter  ended  December 31, 2006 (the "Form  10-QSB").  The
Company is unable,  without  unreasonable  effort and expense,  to file the Form
10-QSB on a timely basis due to unforeseen  delays in the  collection and review
of information  and the completion of drafting the necessary  responses to items
required to be included in the Form 10-QSB.

      The  Company  expects  that the Form  10-QSB  will be filed no later  than
February 20, 2007.


(1)  Name  and  telephone  number  of  person  to  contact  in  regard  to  this

  James A. Hayward                      (631)                    444-6862
  ----------------                   -----------            ------------------
       (Name)                        (Area Code)            (Telephone Number)

(2) Have all other  periodic  reports  required under Section 13 or 15(d) of the
Securities  Exchange Act of 1934 or Section 30 of the Investment  Company Act of
1940  during  the  preceding  12  months  or for such  shorter  period  that the
registrant was required to file such report(s) been filed?  If the answer is no,
identify report(s).

                            |X| Yes           |_| No

(3) Is it anticipated that any significant  change in results of operations from
the  corresponding  period for the last  fiscal  year will be  reflected  by the
earnings statements to be included in the subject report or portion thereof?

                            |_| Yes           |X| No

If so, attach an explanation of the  anticipated  change,  both  narratively and
quantitatively, and, if appropriate, state the reasons why a reasonable estimate
of the results cannot be made.

                           Applied DNA Sciences, Inc.
                  (Name of Registrant as Specified in Charter)

has  caused  this  notification  to be signed on its  behalf by the  undersigned
thereunto duly authorized.

Dated: February 15, 2007                      By:  /s/ JAMES A. HAYWARD
                                                 James A. Hayward
                                                 Chief Executive Officer