Washington, D.C. 20549




(Rule 14a-101)



Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934



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¨   Preliminary Proxy Statement
¨   Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
¨   Definitive Proxy Statement
x   Definitive Additional Materials
¨   Soliciting Material Pursuant to §240.14a-12


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Preliminary Proxy Statement




*** Exercise Your Right to Vote ***

Important Notice Regarding the Availability of Proxy Materials for the

Shareholder Meeting to Be Held on June 19, 2014




Meeting Information            



Meeting Type:



  Annual Meeting


   AVEO PHARMACEUTICALS INC   For holders as of:     April 22, 2014


Date: June 19, 2014




  Time: 10:00 AM EDT


     Location:   the offices of

   Wilmer Cutler Pickering Hale


   and Dorr LLP,


   60 State Street,


   Boston, Massachusetts 02109


     You are receiving this communication because you hold shares in the above named company.




  This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at or easily request a paper copy (see reverse side).

We encourage you to access and review all of the important information contained in the proxy materials before voting.


     See the reverse side of this notice to obtain proxy materials and voting instructions.

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        Before You Vote         

How to Access the Proxy Materials


Proxy Materials Available to VIEW or RECEIVE:



1. Notice & Proxy Statement    2. Form 10-K    3. Shareholder Letter


How to View Online:


Have the information that is printed in the box marked by the arrow LOGO (located on the following page) and visit:


How to Request and Receive a PAPER or E-MAIL Copy:


If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request:


                                 1) BY INTERNET:

                                 2) BY TELEPHONE:     1-800-579-1639

                                 3) BY E-MAIL*:    


* If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow LOGO (located on the following page) in the subject line.

Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before June 05, 2014 to facilitate timely delivery.




        How To Vote         

Please Choose One of the Following Voting Methods



Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares.


Vote By Internet: To vote now by Internet, go to Have the information that is printed in the box marked by the arrow LOGO available and follow the instructions.


Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.



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Voting items      


The Board of Directors recommends you vote FOR the following:

1.    Election of Directors                           
01    Kenneth M. Bate    02    Anthony B. Evnin    03    Tuan Ha-Ngoc    04    Raju Kucherlapati    05    Henri A. Termeer   
06    Robert C. Young                           

The Board of Directors recommends you vote FOR proposals 2, 3 and 4.


2. To approve Amendment No. 1 to the Amended and Restated 2010 Stock Incentive Plan


3. To approve an advisory vote on executive compensation


4. To ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the year ending December 31, 2014

NOTE: In their discretion, the proxies are authorized to vote upon such other business as may properly come before the meeting or any adjournment thereof.

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