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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G

                                (Amendment No. 2)

                    Under the Securities Exchange Act of 1934




                           Senesco Technologies, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    817208408
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                December 31, 2003
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             (Date of Event Which Requires Filing of This Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
                                [ ] Rule 13d-1(b)
                                [X] Rule 13d-1(c)
                                [ ] Rule 13d-1(d)


* The remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

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--------------------------                            --------------------------
CUSIP NO.  817208408              SCHEDULE 13G                 PAGE 2 OF 8 PAGES
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1.                NAME OF REPORTING PERSON/S.S. OR I.R.S. IDENTIFICATION
                  NO. OF ABOVE PERSON

                  SENECA CAPITAL, L.P.
--------------------------------------------------------------------------------
2.                CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*   (A) [ ]
                                                                      (B) [X]
--------------------------------------------------------------------------------
3.                SEC USE ONLY


--------------------------------------------------------------------------------
4.                CITIZENSHIP OR PLACE OF ORGANIZATION

                  DELAWARE
--------------------------------------------------------------------------------
                               5.     SOLE VOTING POWER

                                      0
   NUMBER OF                  --------------------------------------------------
    SHARES                     6.     SHARED VOTING POWER
 BENEFICIALLY
   OWNED BY                           1,319,620
    EACH                      --------------------------------------------------
  REPORTING                    7.     SOLE DISPOSITIVE POWER
   PERSON
    WITH:                             0
                              --------------------------------------------------
                               8.     SHARED DISPOSITIVE POWER

                                      1,319,620
--------------------------------------------------------------------------------
9.                AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  1,319,620
--------------------------------------------------------------------------------
10.               CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
                  CERTAIN SHARES*                                          [ ]
--------------------------------------------------------------------------------
11.               PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  9.47%
--------------------------------------------------------------------------------
12.               TYPE OF REPORTING PERSON*

                  PN
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--------------------------                            --------------------------
CUSIP NO.  817208408              SCHEDULE 13G                 PAGE 3 OF 8 PAGES
--------------------------------------------------------------------------------
1.                NAME OF REPORTING PERSON/S.S. OR I.R.S. IDENTIFICATION
                  NO. OF ABOVE PERSON

                  SENECA CAPITAL ADVISORS, LLC
--------------------------------------------------------------------------------
2.                CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*   (A) [ ]
                                                                      (B) [X]
--------------------------------------------------------------------------------
3.                SEC USE ONLY


--------------------------------------------------------------------------------
4.                CITIZENSHIP OR PLACE OF ORGANIZATION

                  DELAWARE
--------------------------------------------------------------------------------
                               5.     SOLE VOTING POWER

                                      0
   NUMBER OF                  --------------------------------------------------
    SHARES                     6.     SHARED VOTING POWER
 BENEFICIALLY
   OWNED BY                           1,319,620
    EACH                      --------------------------------------------------
  REPORTING                    7.     SOLE DISPOSITIVE POWER
   PERSON
    WITH:                             0
                              --------------------------------------------------
                               8.     SHARED DISPOSITIVE POWER

                                      1,319,620
--------------------------------------------------------------------------------
9.                AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  1,319,620
--------------------------------------------------------------------------------
10.               CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
                  CERTAIN SHARES                                          [ ]
--------------------------------------------------------------------------------
11.               PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  9.47%
--------------------------------------------------------------------------------
12.               TYPE OF REPORTING PERSON

                  00 - LIMITED LIABILITY COMPANY
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--------------------------                            --------------------------
CUSIP NO.  817208408              SCHEDULE 13G                 PAGE 4 OF 8 PAGES
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1.                NAME OF REPORTING PERSON/S.S. OR I.R.S. IDENTIFICATION
                  NO. OF ABOVE PERSON

                  DOUGLAS A. HIRSCH
--------------------------------------------------------------------------------
2.                CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*   (A) [ ]
                                                                      (B) [X]
--------------------------------------------------------------------------------
3.                SEC USE ONLY


--------------------------------------------------------------------------------
4.                CITIZENSHIP OR PLACE OF ORGANIZATION

                  USA
--------------------------------------------------------------------------------
                               5.     SOLE VOTING POWER

                                      0
   NUMBER OF                  --------------------------------------------------
    SHARES                     6.     SHARED VOTING POWER
 BENEFICIALLY
   OWNED BY                           1,319,620
    EACH                      --------------------------------------------------
  REPORTING                    7.     SOLE DISPOSITIVE POWER
   PERSON
    WITH:                             0
                              --------------------------------------------------
                               8.     SHARED DISPOSITIVE POWER

                                      1,319,620
--------------------------------------------------------------------------------
9.                AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

                  1,319,620
--------------------------------------------------------------------------------
10.               CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
                  CERTAIN SHARES                                          [ ]
--------------------------------------------------------------------------------
11.               PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

                  9.47%
--------------------------------------------------------------------------------
12.               TYPE OF REPORTING PERSON

                  IN
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                                  SCHEDULE 13G
CUSIP No. 817208408                                      Page  5   of   8  Pages
          ---------                                           ----    -----


ITEM 1.

      (a) Name of Issuer:    Senesco Technologies,  Inc.
                         ---------------------------------------

      (b) Address of Issuer's Principal Executive Offices:

              303 George Street, Suite 420, New Brunswick, NJ 08901
          -------------------------------------------------------------


ITEM 2.

         (a) Name of Persons Filing:
         (b) Address or principal business office or, if none, residence:
         (c) Citizenship:

                  Seneca Capital, L.P.
                  950 Third Avenue, 29th Floor
                  New York, NY 10022
                  (Delaware limited partnership)

                  Seneca Capital Advisors, LLC
                  950 Third Avenue, 29th Floor
                  New York, NY 10022
                  (Delaware limited liability company)

                  Douglas A. Hirsch
                  c/o Seneca Capital
                  950 Third Avenue, 29th Floor
                  New York, NY 10022
                  (United States Citizen)


Item 2(d).        Title of Class of Securities:  Common stock, $0.01 par value
                                               ---------------------------------

Item 2(e).        CUSIP Number:   817208408
                               -----------------

ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B), OR 13D-2(B), CHECK
        WHETHER THE PERSON FILING IS A:

     (a)  [ ] Broker or Dealer registered under Section 15 of the Act
              (15 U.S.C. 78o).
     (b)  [ ] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
     (c)  [ ] Insurance Company as defined in section 3(a)(19) of the Act
              (15 U.S.C. 78c).
     (d)  [ ] Investment  Company  registered  under section 8 of the Investment
              Company Act of 1940 (15 U.S.C. 80a-8).
     (e)  [ ] Investment  Adviser registered under section 203 of the Investment
              Advisers Act or under the laws of any State
     (f)  [ ] Employee  Benefit  Plan,  Pension  fund  which is  subject to the
              provisions of the Employee  Retirement  Income Security Act of
              1974 or Endowment Fund; see Section 240.13d-1(b)(1)(ii)(F)
     (g)  [ ] A Parent Holding Company  or  control  person, in  accordance with
              Section 240.13d-1(b)(ii)(G)(Note: See Item 7)
     (h)  [ ] A Savings  Association  as defined in Section  3(b) of the Federal
              Deposit Insurance Act (12 U.S.C. 1813)


                                  SCHEDULE 13G

   CUSIP No. 817208408                                   Page  6   of   8  Pages
             ---------                                       -----    -----


     (i)  [ ] A  Church  Plan  that  is  excluded  from  the  definition  of  an
              investment  company under Section  3(c)(14) of the Investment
              Company Act of 1940 (15 U.S.C. 80a-3)
     (j)  [ ] Group, in accordance with Section 240.13d-1(b)(1)(ii)(J)

If this statement is filed pursuant to Rule 240.13d-1(c), check this box.  [X]


ITEM 4.   OWNERSHIP

         Provide the following  information  regarding the aggregate  number and
percentage of the class of securities of the issuer identified in Item 1.

     SENECA CAPITAL, L.P.(1)
      (a) Amount Beneficially Owned:     1,319,620
                                     -------------------------------------------
      (b) Percent of Class:     9.47%
                            ----------------------------------------------------
      (c) Number of shares as to which such person has:

          (i)  sole power to vote or to direct the vote:    0
                                                         -----------------------
          (ii) shared power to vote or to direct the vote:  1,319,620
                                                           ---------------------
          (iii)sole power to dispose or to direct the disposition of:  0
                                                                      ----------
          (iv) shared power to dispose or to direct the disposition of:1,319,620
                                                                       ---------

     SENECA CAPITAL ADVISORS, LLC (2)
      (a) Amount Beneficially Owned:     1,319,620
                                     -------------------------------------------
      (b) Percent of Class:     9.47%
                            ----------------------------------------------------
      (c) Number of shares as to which such person has:

          (i)  sole power to vote or to direct the vote:    0
                                                         -----------------------
          (ii) shared power to vote or to direct the vote:  1,319,620
                                                           ---------------------
          (iii)sole power to dispose or to direct the disposition of:  0
                                                                      ----------
          (iv) shared power to dispose or to direct the disposition of:1,319,620
                                                                       ---------

     DOUGLAS A. HIRSCH (3)
      (a) Amount Beneficially Owned:    1,319,620
                                     -------------------------------------------
      (b) Percent of Class:     9.47%
                            ----------------------------------------------------
      (c) Number of shares as to which such person has:

          (i)  sole power to vote or to direct the vote:    0
                                                         -----------------------
          (ii) shared power to vote or to direct the vote:   1,319,620
                                                           ---------------------
          (iii)sole power to dispose or to direct the disposition of:  0
                                                                      ----------
          (iv) shared power to dispose or to direct the disposition of:1,319,620
                                                                       ---------

(1)       Includes 897,679 shares of common stock which Seneca Capital, L.P. has
          a right to acquire upon the exercise of warrants.

(2)       Shares  reported for Seneca  Capital  Advisors,  LLC represent  shares
          beneficially  owned by Seneca Capital,  L.P. Seneca Capital  Advisors,
          LLC is the sole general partner of Seneca Capital, L.P.


                                  SCHEDULE 13G

   CUSIP No. 817208408                                   Page  7   of   8  Pages
             ---------                                       -----    -----

(3)       Shares reported for Douglas A. Hirsch  represent  shares  beneficially
          owned by Seneca Capital,  L.P. which may be deemed to be controlled by
          Mr. Hirsch because he is the Manager of Seneca Capital  Advisors,  LLC
          (the sole General Partner of Seneca Capital, L.P.).


ITEM 5.   OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

      If this statement is  being  filed to  report the fact that as of the date
hereof the reporting person has ceased to  be the  beneficial owner of more than
five percent of the class of securities, check the following [ ].NOT APPLICABLE.


ITEM 6.   OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

      If any other  person is known to have the right to receive or the power to
direct the receipt of dividends  from,  or the  proceeds  from the sale of, such
securities,  a statement  to that effect  should be included in response to this
item and, if such interest relates to more than five percent of the class,  such
person  should be  identified.  A listing of the  shareholders  of an investment
company registered under the Investment Company Act of 1940 or the beneficiaries
of employees benefit plan,  pension fund or endowment fund is not required.  NOT
APPLICABLE.


ITEM 7.  IDENTIFICATION  AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
         SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

      If a parent  holding  company  has filed this  schedule,  pursuant to Rule
13d-1(b)(ii)(G),  so indicate under Item 3(g) and attach an exhibit  stating the
identity and the Item 3 classification of the relevant  subsidiary.  If a parent
holding  company has filed this schedule  pursuant to Rule  13d-1(c),  attach an
exhibit stating the identification of the relevant subsidiary. NOT APPLICABLE.


ITEM 8.   IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

If a group has filed this schedule pursuant to Rule 13d-1(b)(ii)(J), so indicate
under  Item  3(h)  and  attach  an  exhibit  stating  the  identity  and  Item 3
classification  of each member of the group.  If a group has filed this schedule
pursuant to Rule 13d-1(d), attach an exhibit stating the identity of each member
of the group. NOT APPLICABLE.


ITEM 9.   NOTICE OF DISSOLUTION OF GROUP

      Notice of  dissolution  of a group may be furnished as an exhibit  stating
the date of the  dissolution  and that  all  further  filings  with  respect  to
transactions in the security report on will be filed, if required, by members of
the group, in their individual capacity. NOT APPLICABLE.


ITEM 10.  CERTIFICATION

      By signing  below, I certify that, to the best of my knowledge and belief,
the  securities  referred to above were  acquired  and are held in the  ordinary
course of business and were not acquired and are not held for the purpose of and
do not have the effect of changing or  influencing  the control of the issuer of
such  securities and were not acquired and are not held in connection with or as
a participant in any transaction having that purpose or effect.


                                  SCHEDULE 13G

   CUSIP No. 817208408                                   Page  8   of   8  Pages
             ---------                                       -----    -----


                                    SIGNATURE

After  reasonable  inquiry and to the best of my knowledge and belief,  I hereby
certify that the information  set forth in this statement is true,  complete and
correct.



Date:  February 12, 2004



SENECA CAPITAL, L.P.

By Seneca Capital Advisors, LLC, its General Partner


By: /s/ Douglas A. Hirsch
   ----------------------------------------------
   Douglas A. Hirsch, Its Managing Member



SENECA CAPITAL ADVISORS, LLC


By: /s/ Douglas A. Hirsch
   ----------------------------------------------
   Douglas A. Hirsch, Its Managing Member




By: /s/ Douglas A. Hirsch
   ----------------------------------------------
   Douglas A. Hirsch, Individually