Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HOLTZ DAVID B
   2. Issuer Name and Ticker or Trading Symbol
INTEGRA LIFESCIENCES HOLDINGS CORP [IART] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Sr. VP, Finance
(Last)
(First)
(Middle)
311 C ENTERPRISE DRIVE		 3. Date of Earliest Transaction (Month/Day/Year)
12/18/2006
(Street)

PLAINSBORO, NJ 08536		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/18/2006   M   2,010 A $ 26.7 12,258 D  
Common Stock 12/18/2006   M   1,669 A $ 14.87 13,927 D  
Common Stock 12/18/2006   M   250 A $ 17.6 14,177 D  
Common Stock 12/18/2006   M   2,196 A $ 17.65 16,373 D  
Common Stock 12/18/2006   M   1,252 A $ 22.78 17,625 D  
Common Stock 12/18/2006   M   770 A $ 32.39 18,395 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Incentive Stock Option (right to buy) $ 26.7 12/18/2006   M     2,010   (1) 12/17/2007 Common Stock 2,010 $ 0 0 D  
Incentive Stock Option (right to buy) $ 14.87 12/18/2006   M     1,669   (2) 08/02/2008 Common Stock 1,669 $ 0 0 D  
Incentive Stock Option (right to buy) $ 17.6 12/18/2006   M     250   (3) 12/16/2008 Common Stock 250 $ 0 0 D  
Incentive Stock Option (right to buy) $ 17.65 12/18/2006   M     2,196   (4) 12/31/2008 Common Stock 2,196 $ 0 200 D  
Incentive Stock Option (right to buy) $ 22.78 12/18/2006   M     1,252   (5) 04/07/2009 Common Stock 1,252 $ 0 500 D  
Incentive Stock Option (right to buy) $ 32.39 12/18/2006   M     770   (6) 11/03/2009 Common Stock 770 $ 0 230 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HOLTZ DAVID B
311 C ENTERPRISE DRIVE
PLAINSBORO, NJ 08536		       Sr. VP, Finance  

Signatures

 /s/ Jeffrey Hellman, Attorney-in-Fact   12/20/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These options vested over time, with all options having fully vested on December 17, 2005.
(2) These options vested over time, with all options having fully vested on August 2, 2006.
(3) These options vested over time, with all options having fully vested on December 16, 2006.
(4) On a combined basis, 25% of this option grant and a Non-Qualified Stock option grant made on the date of this grant vested one year after the December 31, 2002 grant date with the remaining 75% vesting monthly thereafter over 36 months.
(5) On a combined basis, 25% of this option grant and a Non-Qualified Stock option grant made on the date of this grant vested one year after the April 7, 2003 grant date with the remaining 75% vesting monthly thereafter over 36 months.
(6) On a combined basis, 25% of this option grant and a Non-Qualified Stock option grant made on the date of this grant vested one year after the November 3, 2003 grant date with the remaining 75% vesting monthly thereafter over 36 months.

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