Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  RA CAPITAL MANAGEMENT, LLC
 2. Date of Event Requiring Statement (Month/Day/Year)
08/08/2007		 3. Issuer Name and Ticker or Trading Symbol
CURIS INC [CRIS]
(Last)
(First)
(Middle)
C/O RA CAPITAL MANAGEMENT, LLC, 111 HUNTINGTON AVE., SUITE 610		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
08/15/2007
(Street)

BOSTON, MA 02199		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 7,550,564
I
See Footnote (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
RA CAPITAL MANAGEMENT, LLC
C/O RA CAPITAL MANAGEMENT, LLC
111 HUNTINGTON AVE., SUITE 610
BOSTON, MA 02199		     X    
ALDRICH RICHARD
C/O RA CAPITAL MANAGEMENT, LLC
111 HUNTINGTON AVE., SUITE 610
BOSTON, MA 02199		     X    
Kolchinsky Peter
C/O RA CAPITAL MANAGEMENT, LLC
111 HUNTINGTON AVE., SUITE 610
BOSTON, MA 02199		     X    
RA Capital Biotech Fund LP
C/O RA CAPITAL MANAGEMENT, LLC
111 HUNTINGTON AVE., SUITE 610
BOSTON, MA 02199		     X    
RA Capital Biotech Fund II, L.P.
C/O RA CAPITAL MANAGEMENT, LLC
111 HUNTINGTON AVE., SUITE 610
BOSTON, MA 02199		     X    

Signatures

/s/ Peter Kolchinsky, Manager of RA Capital Management, LLC 02/27/2008
**Signature of Reporting Person Date
Richard H. Aldrich 02/27/2008
**Signature of Reporting Person Date
Peter Kolchinsky 02/27/2008
**Signature of Reporting Person Date
Peter Kolchinsky, Manager of RA Capital Management, LLC, the General Partner of RA Capital Biotech Fund, L.P. 02/27/2008
**Signature of Reporting Person Date
Peter Kolchinsky, Manager of RA Capital Management, LLC, the General Partner of RA Capital Biotech Fund II, L.P. 02/27/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) 1. Includes 29,472 shares held by RA Capital Biotech Fund, L.P. ("Fund I") and 528 shares held by RA Capital Biotech Fund II, L.P. ("Fund II") that were inadvertently omitted from the reporting persons' original Form 3. These shares were held prior to an acquisition of stock and warrants made by Fund I and Fund II on August 8, 2007. Currently, Fund I holds 7,417,674 shares and Fund II holds 132,890 shares. RA Capital Management, LLC (the "General Partner") is the general partner of each of Fund I and Fund II, and Richard H. Aldrich and Peter Kolchinsky are the sole managers of the General Partner. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the exten of his or her pecuniary interest therein, if any.

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