Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Bloch Stephen M
2. Date of Event Requiring Statement (Month/Day/Year)
05/30/2007
3. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD]
(Last)
(First)
(Middle)
C/O CANAAN PARTNERS, 285 RIVERSIDE AVENUE, SUITE 250
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

WESTPORT, CT 06880
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock 05/04/2004   (3) Common Stock 449,110 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series B Convertible Preferred Stock 05/04/2004   (3) Common Stock 16,771 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series B Convertible Preferred Stock 03/24/2005   (3) Common Stock 449,110 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series B Convertible Preferred Stock 03/24/2005   (3) Common Stock 16,771 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series C Convertible Preferred Stock 08/16/2005   (3) Common Stock 437,415 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series C Convertible Preferred Stock 08/16/2005   (3) Common Stock 16,334 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series C Convertible Preferred Stock 04/17/2006   (3) Common Stock 437,415 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series C Convertible Preferred Stock 04/17/2006   (3) Common Stock 16,334 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series D Convertible Preferred Stock 09/13/2006   (3) Common Stock 98,029 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series D Convertible Preferred Stock 09/13/2006   (3) Common Stock 3,660 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series D Convertible Preferred Stock 09/13/2006   (3) Common Stock 98,029 (3) $ 0 (3) I Canaan Equity III, L.P. (1)
Series D Convertible Preferred Stock 09/13/2006   (3) Common Stock 3,660 (3) $ 0 (3) I Canaan Equity III Entrepreneurs, LLC (2)
Series B Convertible Preferred Stock Warrant (right to buy) 05/04/2004   (4) Series B Convertible Preferred Stock 13,669 $ 6.375 I Canaan Equity III, L.P. (1)
Series B Convertible Preferred Stock Warrant (right to buy) 05/04/2004   (4) Series B Convertible Preferred Stock 510 $ 6.375 I Canaan Equity III Entrepreneurs, LLC (2)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Bloch Stephen M
C/O CANAAN PARTNERS
285 RIVERSIDE AVENUE, SUITE 250
WESTPORT, CT 06880
  X   X    

Signatures

/s/ Stephen Bloch 05/30/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The reporting person is a member of Canaan Equity Partners III, LLC, which is the general partner of Canaan Equity III, L.P. Voting and investment power over these shares is exercised by Canaan Equity Partners III, LLC in its role as general partner of Canaan Equity III, L.P. The reporting person disclaims beneficial ownership of these shares except to the extent of his proportionate pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purposes of Section 16 or for any other purpose.
(2) The reporting person is a member of Canaan Equity Partners III, LLC, which is the general partner of Canaan Equity III Entrepreneurs, LLC Voting and investment power over these shares is exercised by Canaan Equity Partners III, LLC in its role as manager of Canaan Equity III Entrepreneurs, LLC The reporting person disclaims beneficial ownership of these shares except to the extent of his proportionate pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purposes of Section 16 or for any other purpose.
(3) Each share is convertible and will automatically convert on a 1-for-1 basis into the Issuer's common stock upon the closing of the Issuer's initial public offering of common stock pursuant to an effecive registration statement filed with the U.S. Securities and Exchange Commission. These shares have no expiration date.
(4) The warrants to purchase Series B Convertible Preferred Stock will be automatically net exercised immediately prior to the closing of the Issuer's initial public offering.

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