Ownership Submission
FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person *
BIENAIME JEAN JACQUES
 2. Issuer Name and Ticker or Trading Symbol
BIOMARIN PHARMACEUTICAL INC [BMRN] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Business Officer
(Last)
(First)
(Middle)

C/O BIOMARIN PHARMACEUTICAL INC., 105 DIGITAL DRIVE		 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
05/12/2012
(Street)


NOVATO, CA 94949		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price
Common Stock 05/12/2012   F4 7,820 (1) D $ 38 149,446 D  
Common Stock 10/23/2012   G4 13,545 (2) D $ 0 135,901 D  
Common Stock 10/23/2012   G4 13,545 (2) A $ 0 13,545 I Shares held by Family Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option $ 12.99 10/19/2012   G   10,000   (4)(3) 05/10/2016 Common Stock
10,000
$ 0 0
D
 
Employee Stock Option $ 12.99 10/19/2012   G   10,000   (4)(3) 05/10/2016 Common Stock
10,000
$ 0 0
D
 
Employee Stock Option $ 12.99 10/19/2012   G   10,000   (4)(3) 05/10/2016 Common Stock
10,000
$ 0 0
D
 
Employee Stock Option $ 12.99 10/19/2012   G   10,000   (4)(3) 05/10/2016 Common Stock
10,000
$ 0 0
D
 
Employee Stock Option $ 12.99 10/19/2012   G   20,000   (4)(3) 05/10/2016 Common Stock
20,000
$ 0 0
D
 
Employee Stock Option $ 6.46 10/23/2012   G   45,764   (4) 05/10/2015 Common Stock
45,764
$ 0 0
D
 
Employee Stock Option $ 9.86 10/23/2012   G   9,500   (4) 11/10/2015 Common Stock
9,500
$ 0 0
D
 
Employee Stock Option $ 12.99 10/23/2012   G   352,500   (4) 05/10/2016 Common Stock
352,500
$ 0 0
D
 
Employee Stock Option $ 17.54 10/23/2012   G   250,000   (4) 11/19/2016 Common Stock
250,000
$ 0 0
D
 
Employee Stock Option $ 17.33 10/23/2012   G   160,000   (4) 06/06/2017 Common Stock
160,000
$ 0 0
D
 
Employee Stock Option $ 38.59 10/23/2012   G   425,000   (4) 05/21/2018 Common Stock
425,000
$ 0 0
D
 
Employee Stock Option $ 17.86 10/23/2012   G   22,000   (5) 12/16/2018 Common Stock
22,000
$ 0 0
D
 
Employee Stock Option $ 14.39 10/23/2012   G   240,000   (6) 05/11/2019 Common Stock
240,000
$ 0 0
D
 
Employee Stock Option $ 21.51 10/23/2012   G   280,000   (7) 05/11/2020 Common Stock
280,000
$ 0 0
D
 
Employee Stock Option $ 26.49 10/23/2012   G   280,000   (8) 05/11/2021 Common Stock
280,000
$ 0 0
D
 
Employee Stock Option $ 37.46 10/23/2012   G   140,000   (9) 05/07/2022 Common Stock
140,000
$ 0 0
D
 
Employee Stock Option $ 12.99 10/19/2012   G 10,000     (4)(3) 05/10/2016 Common Stock
10,000
$ 0 10,000
I
Held in Irrevocable Trust for Guillaume Bienaime
Employee Stock Option $ 12.99 10/19/2012   G 10,000     (4)(3) 05/10/2016 Common Stock
10,000
$ 0 10,000
I
Held in Irrevocable Trust for Marc Bienaime
Employee Stock Option $ 12.99 10/19/2012   G 10,000     (3) 05/10/2016 Common Stock
10,000
$ 0 10,000
I
Held in Irrevocable Trust for Pierre Bienaime
Employee Stock Option $ 12.99 10/19/2012   G 10,000     (4)(3) 05/10/2016 Common Stock
10,000
$ 0 10,000
I
Held in Irrevocable Trust for Paul Bienaime
Employee Stock Option $ 12.99 10/19/2012   G 20,000     (4)(3) 05/10/2016 Common Stock
20,000
$ 0 20,000
I
Held in Irrevocable Trust for Aurelie Mitsuki Bienaime and Anais Kimiko Bienaime
Employee Stock Option $ 6.46 10/23/2012   G 45,764     (4) 05/10/2015 Common Stock
45,764
$ 0 45,764 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 9.86 10/23/2012   G 9,500     (4) 11/10/2015 Common Stock
9,500
$ 0 9,500 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Optio $ 12.99 10/23/2012   G 352,500     (4) 05/10/2016 Common Stock
352,500
$ 0 352,500 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 17.54 10/23/2012   G 250,000     (4) 11/19/2016 Common Stock
250,000
$ 0 250,000 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 17.33 10/23/2012   G 160,000     (4) 06/06/2017 Common Stock
160,000
$ 0 160,000 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 38.59 10/23/2012   G 425,000     (4) 05/21/2018 Common Stock
425,000
$ 0 425,000 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 17.86 10/23/2012   G 22,000     (5) 12/16/2018 Common Stock
22,000
$ 0 22,000 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 14.39 10/23/2012   G 240,000     (6) 05/11/2019 Common Stock
240,000
$ 0 240,000 (10)
I
Shares held by Bienaime Family Trust
Employee Stock Option $ 21.51 10/23/2012   G 280,000     (7) 05/11/2020 Common Stock
280,000
$ 0 280,000 (10)
I
Shares held by Bienaime Family Trust

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
BIENAIME JEAN JACQUES
C/O BIOMARIN PHARMACEUTICAL INC.
105 DIGITAL DRIVE
NOVATO, CA 94949		   X     Chief Business Officer  

Signatures

/s/ Laura Woodhead, Attorney-in-Fact 02/14/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) On May 12, 2012 the reporting person had 16,750 restricted stock units from prior grants vest of which 7,820 shares were withheld for the payment of taxes.
(2) On October 23, 2012 the reporting person gifted 13,545 shares of common stock to a family trust. The reporting person and his spouse are trustees.
(3) On October 19, 2012 the reporting person gifted shares to his children's trusts in the amount listed. The reporting person's spouse is the trustee of each child's trust.
(4) This stock option is fully vested and therefore is currently exercisable for 100% of shares.
(5) The option was granted on 12/17/08. It vested 6/48 six months after grant, and vests 1/48 each month thereater.
(6) The option was granted on 5/12/09. It vested 6/48 six months after grant, and vests 1/48 each month thereater.
(7) The option was granted on 5/12/10. It vested 6/48 six months after grant, and vests 1/48 each month thereater.
(8) The option was granted on 5/12/11. It vested 6/48 six months after grant, and vests 1/48 each month thereater.
(9) The option was granted on 5/8/12. It vested 6/48 six months after grant, and vests 1/48 each month thereater.
(10) Stock option exercises completed by reporting person between October 24, 2012 to December 31, 2012 were inadvertently reported on Form 4s as transactions for the reporting person's direct holdings and should have been reported as transactions for the reporting person's indirect holding in Bienaime Family trust following the October 23, 2012 gift of all outstanding stock options held directly to the Bienaime Family Trust.

Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.